SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_A_RALA600_1 (ESTROGEN RECEPTOR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	THR A 118 ALA A 158 LEU A 156 LEU A 165 ILE A 112	None	1.24A	1errA-3e1hA: undetectable	1errA-3e1hA: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IOL_A_ESTA400_1 (ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 11	VAL A 261 LEU A 250 GLY A 206 HIS A 305 PHE A 210	None	1.37A	1iolA-3e1hA: undetectable	1iolA-3e1hA: 23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.14A	1qzfA-3e1hA: undetectable	1qzfA-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.14A	1qzfB-3e1hA: undetectable	1qzfB-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 116 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.15A	1qzfC-3e1hA: undetectable	1qzfC-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.15A	1qzfC-3e1hA: undetectable	1qzfC-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.14A	1qzfD-3e1hA: undetectable	1qzfD-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.15A	1qzfE-3e1hA: undetectable	1qzfE-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X1A_A_SAMA4264_0 (CRTF-RELATED PROTEIN)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	ALA A 157 GLY A 377 GLY A 375 ILE A 150 LEU A 270	None	1.06A	1x1aA-3e1hA: undetectable	1x1aA-3e1hA: 25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVD_B_SAMB601_0 (CATECHOL-O-METHYLTRA NSFERASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	MET A 382 GLY A 155 ALA A 182 ALA A 158 ARG A 160	None	1.39A	2avdB-3e1hA: undetectable	2avdB-3e1hA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 116 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.12A	2oipC-3e1hA: undetectable	2oipC-3e1hA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.20A	2oipC-3e1hA: undetectable	2oipC-3e1hA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QMM_B_SAMB301_0 (UPF0217 PROTEIN AF_1056)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 11	LEU A 219 ILE A 178 SER A 13 LEU A 12 CYH A 166	None	1.01A	2qmmA-3e1hA: undetectable 2qmmB-3e1hA: undetectable	2qmmA-3e1hA: 21.21 2qmmB-3e1hA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_H_CPFH1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	3 / 3	ARG A 350 GLU A 353 SER A 211	None	0.81A	2xctD-3e1hA: undetectable	2xctD-3e1hA: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI9_X_SAMX501_0 (UPF0217 PROTEIN MJ1640)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 9	LEU A 219 ILE A 178 SER A 13 LEU A 12 CYH A 166	None	1.05A	3ai9X-3e1hA: undetectable	3ai9X-3e1hA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 8	GLY A 307 SER A 339 SER A 211 THR A 343	None	0.63A	3d41A-3e1hA: undetectable	3d41A-3e1hA: 25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 116 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.13A	3hj3C-3e1hA: undetectable	3hj3C-3e1hA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 235 THR A 118	None	1.14A	3hj3C-3e1hA: undetectable	3hj3C-3e1hA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 180 ALA A 182 LEU A 156 LEU A 385 THR A 118	None	1.16A	3hj3C-3e1hA: undetectable	3hj3C-3e1hA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 380 VAL A 267 ALA A 271 SER A 274 LEU A 275	None	1.07A	3ln1A-3e1hA: undetectable	3ln1A-3e1hA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 380 VAL A 267 ALA A 271 SER A 274 LEU A 275	None	1.07A	3ln1B-3e1hA: undetectable	3ln1B-3e1hA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 380 VAL A 267 ALA A 271 SER A 274 LEU A 275	None	1.06A	3ln1C-3e1hA: undetectable	3ln1C-3e1hA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUD_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	GLY A 90 ALA A 94 ALA A 182 ALA A 342 SER A 340	None	0.97A	3sudA-3e1hA: undetectable	3sudA-3e1hA: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KY8_A_MTXA603_1 (BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLA TE REDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.38A	4ky8A-3e1hA: undetectable	4ky8A-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KY8_B_MTXB603_1 (BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLA TE REDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.33A	4ky8B-3e1hA: undetectable	4ky8B-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KY8_C_MTXC603_1 (BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLA TE REDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.39A	4ky8C-3e1hA: undetectable	4ky8C-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KY8_D_MTXD603_1 (BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLA TE REDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.37A	4ky8D-3e1hA: undetectable	4ky8D-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KY8_E_MTXE603_1 (BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLA TE REDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.38A	4ky8E-3e1hA: undetectable	4ky8E-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1Z_B_MXMB807_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	MET A 45 VAL A 48 LEU A 49 VAL A 190 LEU A 194	None	1.04A	4o1zB-3e1hA: undetectable	4o1zB-3e1hA: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_A_MTXA604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.36A	4q0dA-3e1hA: undetectable	4q0dA-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_B_MTXB604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.36A	4q0dB-3e1hA: undetectable	4q0dB-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_E_MTXE604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	VAL A 116 ALA A 182 LEU A 156 ILE A 14 LEU A 235 THR A 118	None	1.36A	4q0dE-3e1hA: undetectable	4q0dE-3e1hA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	ILE A 150 CYH A 120 GLY A 155 GLY A 154	None	0.77A	5a06A-3e1hA: undetectable	5a06A-3e1hA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_B_SORB1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	ILE A 150 CYH A 120 GLY A 155 GLY A 154	None	0.77A	5a06B-3e1hA: undetectable	5a06B-3e1hA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_C_SORC1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	ILE A 150 CYH A 120 GLY A 155 GLY A 154	None	0.76A	5a06C-3e1hA: undetectable	5a06C-3e1hA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_E_SORE1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	ILE A 150 CYH A 120 GLY A 155 GLY A 154	None	0.77A	5a06E-3e1hA: undetectable	5a06E-3e1hA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_F_SORF1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	ILE A 150 CYH A 120 GLY A 155 GLY A 154	None	0.76A	5a06F-3e1hA: undetectable	5a06F-3e1hA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EQB_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	6 / 12	GLY A 375 ILE A 232 TYR A 233 GLY A 16 GLY A 18 HIS A 305	None	1.21A	5eqbA-3e1hA: undetectable	5eqbA-3e1hA: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESL_A_1YNA701_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	GLY A 375 ILE A 232 TYR A 233 GLY A 18 HIS A 305	None	1.15A	5eslA-3e1hA: undetectable	5eslA-3e1hA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_A_ID8A601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	5 / 12	VAL A 380 VAL A 267 ALA A 271 SER A 274 LEU A 275	None	1.14A	5ikrA-3e1hA: undetectable	5ikrA-3e1hA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	VAL A 347 ILE A 334 SER A 339 THR A 343	None	0.96A	5vkqA-3e1hA: undetectable 5vkqD-3e1hA: undetectable	5vkqA-3e1hA: 14.09 5vkqD-3e1hA: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1802_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	SER A 339 THR A 343 VAL A 347 ILE A 334	None	0.99A	5vkqA-3e1hA: undetectable 5vkqB-3e1hA: undetectable	5vkqA-3e1hA: 14.09 5vkqB-3e1hA: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 8	SER A 339 THR A 343 VAL A 347 ILE A 334	None	0.96A	5vkqB-3e1hA: undetectable 5vkqC-3e1hA: undetectable	5vkqB-3e1hA: 14.09 5vkqC-3e1hA: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_D_PCFD1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 7	SER A 339 THR A 343 VAL A 347 ILE A 334	None	0.97A	5vkqC-3e1hA: undetectable 5vkqD-3e1hA: undetectable	5vkqC-3e1hA: 14.09 5vkqD-3e1hA: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BOC_A_EU7A102_0 (MATRIX PROTEIN 2)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	4 / 6	SER A 313 ALA A 318 SER A 317 ALA A 271	None	0.91A	6bocA-3e1hA: undetectable 6bocB-3e1hA: undetectable 6bocC-3e1hA: undetectable 6bocD-3e1hA: undetectable	6bocA-3e1hA: 4.95 6bocB-3e1hA: 4.95 6bocC-3e1hA: 4.95 6bocD-3e1hA: 4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DGX_A_017A101_2 (PROTEASE)	3e1h	PUTATIVE UNCHARACTERIZED PROTEIN (Neurospora crassa)	3 / 3	GLY A 11 ASP A 234 ILE A 14	None	0.43A	6dgxB-3e1hA: undetectable	6dgxB-3e1hA: 13.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ERR_A_RALA600_1","ESTROGEN RECEPTOR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"THR A 118;ALA A 158;LEU A 156;LEU A 165;ILE A 112","None","1.24A","1errA-3e1hA:undetectable","1errA-3e1hA:22.88"],["1IOL_A_ESTA400_1","ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 261;LEU A 250;GLY A 206;HIS A 305;PHE A 210","None","1.37A","1iolA-3e1hA:undetectable","1iolA-3e1hA:23.82"],["1QZF_A_FOLA605_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.14A","1qzfA-3e1hA:undetectable","1qzfA-3e1hA:21.25"],["1QZF_B_FOLB609_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.14A","1qzfB-3e1hA:undetectable","1qzfB-3e1hA:21.25"],["1QZF_C_FOLC613_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 116;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.15A","1qzfC-3e1hA:undetectable","1qzfC-3e1hA:21.25"],["1QZF_C_FOLC613_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.15A","1qzfC-3e1hA:undetectable","1qzfC-3e1hA:21.25"],["1QZF_D_FOLD617_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.14A","1qzfD-3e1hA:undetectable","1qzfD-3e1hA:21.25"],["1QZF_E_FOLE621_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.15A","1qzfE-3e1hA:undetectable","1qzfE-3e1hA:21.25"],["1X1A_A_SAMA4264_0","CRTF-RELATED PROTEIN","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"ALA A 157;GLY A 377;GLY A 375;ILE A 150;LEU A 270","None","1.06A","1x1aA-3e1hA:undetectable","1x1aA-3e1hA:25.42"],["2AVD_B_SAMB601_0","CATECHOL-O-METHYLTRANSFERASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"MET A 382;GLY A 155;ALA A 182;ALA A 158;ARG A 160","None","1.39A","2avdB-3e1hA:undetectable","2avdB-3e1hA:20.39"],["2OIP_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 116;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.12A","2oipC-3e1hA:undetectable","2oipC-3e1hA:21.20"],["2OIP_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.20A","2oipC-3e1hA:undetectable","2oipC-3e1hA:21.20"],["2QMM_B_SAMB301_0","UPF0217 PROTEIN AF_1056","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"LEU A 219;ILE A 178;SER A  13;LEU A  12;CYH A 166","None","1.01A","2qmmA-3e1hA:undetectable;2qmmB-3e1hA:undetectable","2qmmA-3e1hA:21.21;2qmmB-3e1hA:21.21"],["2XCT_H_CPFH1020_1","DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",3,"ARG A 350;GLU A 353;SER A 211","None","0.81A","2xctD-3e1hA:undetectable","2xctD-3e1hA:20.64"],["3AI9_X_SAMX501_0","UPF0217 PROTEIN MJ1640","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"LEU A 219;ILE A 178;SER A  13;LEU A  12;CYH A 166","None","1.05A","3ai9X-3e1hA:undetectable","3ai9X-3e1hA:18.14"],["3D41_A_FCNA4001_1","FOMA PROTEIN","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"GLY A 307;SER A 339;SER A 211;THR A 343","None","0.63A","3d41A-3e1hA:undetectable","3d41A-3e1hA:25.65"],["3HJ3_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 116;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.13A","3hj3C-3e1hA:undetectable","3hj3C-3e1hA:21.57"],["3HJ3_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 235;THR A 118","None","1.14A","3hj3C-3e1hA:undetectable","3hj3C-3e1hA:21.57"],["3HJ3_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 180;ALA A 182;LEU A 156;LEU A 385;THR A 118","None","1.16A","3hj3C-3e1hA:undetectable","3hj3C-3e1hA:21.57"],["3LN1_A_CELA682_1","PROSTAGLANDIN G\/H SYNTHASE 2","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 380;VAL A 267;ALA A 271;SER A 274;LEU A 275","None","1.07A","3ln1A-3e1hA:undetectable","3ln1A-3e1hA:22.17"],["3LN1_B_CELB682_1","PROSTAGLANDIN G\/H SYNTHASE 2","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 380;VAL A 267;ALA A 271;SER A 274;LEU A 275","None","1.07A","3ln1B-3e1hA:undetectable","3ln1B-3e1hA:22.17"],["3LN1_C_CELC682_1","PROSTAGLANDIN G\/H SYNTHASE 2","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 380;VAL A 267;ALA A 271;SER A 274;LEU A 275","None","1.06A","3ln1C-3e1hA:undetectable","3ln1C-3e1hA:22.17"],["3SUD_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"GLY A  90;ALA A  94;ALA A 182;ALA A 342;SER A 340","None","0.97A","3sudA-3e1hA:undetectable","3sudA-3e1hA:20.48"],["4KY8_A_MTXA603_1","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.38A","4ky8A-3e1hA:undetectable","4ky8A-3e1hA:21.25"],["4KY8_B_MTXB603_1","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.33A","4ky8B-3e1hA:undetectable","4ky8B-3e1hA:21.25"],["4KY8_C_MTXC603_1","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.39A","4ky8C-3e1hA:undetectable","4ky8C-3e1hA:21.25"],["4KY8_D_MTXD603_1","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.37A","4ky8D-3e1hA:undetectable","4ky8D-3e1hA:21.25"],["4KY8_E_MTXE603_1","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.38A","4ky8E-3e1hA:undetectable","4ky8E-3e1hA:21.25"],["4O1Z_B_MXMB807_1","PROSTAGLANDIN G\/H SYNTHASE 1","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"MET A  45;VAL A  48;LEU A  49;VAL A 190;LEU A 194","None","1.04A","4o1zB-3e1hA:undetectable","4o1zB-3e1hA:20.88"],["4Q0D_A_MTXA604_1","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.36A","4q0dA-3e1hA:undetectable","4q0dA-3e1hA:21.25"],["4Q0D_B_MTXB604_1","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.36A","4q0dB-3e1hA:undetectable","4q0dB-3e1hA:21.25"],["4Q0D_E_MTXE604_1","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"VAL A 116;ALA A 182;LEU A 156;ILE A  14;LEU A 235;THR A 118","None","1.36A","4q0dE-3e1hA:undetectable","4q0dE-3e1hA:21.25"],["5A06_A_SORA1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"ILE A 150;CYH A 120;GLY A 155;GLY A 154","None","0.77A","5a06A-3e1hA:undetectable","5a06A-3e1hA:21.15"],["5A06_B_SORB1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"ILE A 150;CYH A 120;GLY A 155;GLY A 154","None","0.77A","5a06B-3e1hA:undetectable","5a06B-3e1hA:21.15"],["5A06_C_SORC1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"ILE A 150;CYH A 120;GLY A 155;GLY A 154","None","0.76A","5a06C-3e1hA:undetectable","5a06C-3e1hA:21.15"],["5A06_E_SORE1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"ILE A 150;CYH A 120;GLY A 155;GLY A 154","None","0.77A","5a06E-3e1hA:undetectable","5a06E-3e1hA:21.15"],["5A06_F_SORF1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"ILE A 150;CYH A 120;GLY A 155;GLY A 154","None","0.76A","5a06F-3e1hA:undetectable","5a06F-3e1hA:21.15"],["5EQB_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",6,"GLY A 375;ILE A 232;TYR A 233;GLY A  16;GLY A  18;HIS A 305","None","1.21A","5eqbA-3e1hA:undetectable","5eqbA-3e1hA:22.28"],["5ESL_A_1YNA701_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"GLY A 375;ILE A 232;TYR A 233;GLY A  18;HIS A 305","None","1.15A","5eslA-3e1hA:undetectable","5eslA-3e1hA:22.75"],["5IKR_A_ID8A601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",5,"VAL A 380;VAL A 267;ALA A 271;SER A 274;LEU A 275","None","1.14A","5ikrA-3e1hA:undetectable","5ikrA-3e1hA:22.69"],["5VKQ_A_PCFA1805_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"VAL A 347;ILE A 334;SER A 339;THR A 343","None","0.96A","5vkqA-3e1hA:undetectable;5vkqD-3e1hA:undetectable","5vkqA-3e1hA:14.09;5vkqD-3e1hA:14.09"],["5VKQ_B_PCFB1802_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"SER A 339;THR A 343;VAL A 347;ILE A 334","None","0.99A","5vkqA-3e1hA:undetectable;5vkqB-3e1hA:undetectable","5vkqA-3e1hA:14.09;5vkqB-3e1hA:14.09"],["5VKQ_C_PCFC1803_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"SER A 339;THR A 343;VAL A 347;ILE A 334","None","0.96A","5vkqB-3e1hA:undetectable;5vkqC-3e1hA:undetectable","5vkqB-3e1hA:14.09;5vkqC-3e1hA:14.09"],["5VKQ_D_PCFD1803_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"SER A 339;THR A 343;VAL A 347;ILE A 334","None","0.97A","5vkqC-3e1hA:undetectable;5vkqD-3e1hA:undetectable","5vkqC-3e1hA:14.09;5vkqD-3e1hA:14.09"],["6BOC_A_EU7A102_0","MATRIX PROTEIN 2","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",4,"SER A 313;ALA A 318;SER A 317;ALA A 271","None","0.91A","6bocA-3e1hA:undetectable;6bocB-3e1hA:undetectable;6bocC-3e1hA:undetectable;6bocD-3e1hA:undetectable","6bocA-3e1hA:4.95;6bocB-3e1hA:4.95;6bocC-3e1hA:4.95;6bocD-3e1hA:4.95"],["6DGX_A_017A101_2","PROTEASE","3e1h","PUTATIVE UNCHARACTERIZED PROTEIN","Neurospora crassa",3,"GLY A  11;ASP A 234;ILE A  14","None","0.43A","6dgxB-3e1hA:undetectable","6dgxB-3e1hA:13.41"]]