SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 ALA A 482
LEU A 709
LEU A 708
LEU A 716
 None
 0.95A 1ereE-3e1sA:
undetectable		 1ereE-3e1sA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 ALA A 482
LEU A 709
LEU A 708
LEU A 716
 None
 0.94A 1ereF-3e1sA:
undetectable		 1ereF-3e1sA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 VAL A 659
GLY A 658
LEU A 657
GLY A 688
LEU A 536
 None
 1.10A 1fduA-3e1sA:
undetectable		 1fduA-3e1sA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 7 LEU A 479
LEU A 444
GLY A 441
LEU A 308
 None
 0.90A 1gtiA-3e1sA:
undetectable		 1gtiA-3e1sA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 SER A 686
PHE A 684
SER A 689
LEU A 668
HIS A 664
 None
 1.22A 1q23D-3e1sA:
undetectable
1q23E-3e1sA:
undetectable		 1q23D-3e1sA:
16.33
1q23E-3e1sA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 7 LEU A 432
GLU A 383
ALA A 456
ALA A 451
 None
 0.78A 1sn0B-3e1sA:
undetectable
1sn0D-3e1sA:
undetectable		 1sn0B-3e1sA:
12.15
1sn0D-3e1sA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 THR A 364
VAL A 461
GLY A 462
ILE A 486
 None
 0.83A 2a1mB-3e1sA:
undetectable		 2a1mB-3e1sA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 6 PHE A 603
THR A 407
VAL A 408
LEU A 412
 None
 1.08A 2e1qA-3e1sA:
undetectable		 2e1qA-3e1sA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 6 PHE A 603
THR A 407
VAL A 408
LEU A 412
 None
 1.03A 2e1qC-3e1sA:
undetectable		 2e1qC-3e1sA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.24A 2oaxB-3e1sA:
undetectable		 2oaxB-3e1sA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.22A 2oaxC-3e1sA:
undetectable		 2oaxC-3e1sA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.24A 2oaxD-3e1sA:
undetectable		 2oaxD-3e1sA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.25A 2oaxE-3e1sA:
undetectable		 2oaxE-3e1sA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.23A 2oaxF-3e1sA:
undetectable		 2oaxF-3e1sA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 6 THR A 224
ARG A 275
THR A 196
ASP A 207
 None
 1.28A 2okcA-3e1sA:
undetectable		 2okcA-3e1sA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 6 THR A 224
ARG A 275
THR A 196
ASP A 207
 None
 1.28A 2okcB-3e1sA:
2.0		 2okcB-3e1sA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		3 / 3 ARG A 701
VAL A 645
THR A 675
 None
 0.83A 3cyxA-3e1sA:
undetectable		 3cyxA-3e1sA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN0_A_DMOA551_1
(ARGINASE-1)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 9 ASP A 463
GLY A 462
ASP A 435
GLU A 436
THR A 364
 None
 1.29A 3gn0A-3e1sA:
3.2		 3gn0A-3e1sA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN0_B_DMOB552_1
(ARGINASE-1)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 9 ASP A 463
GLY A 462
ASP A 435
GLU A 436
THR A 364
 None
 1.32A 3gn0B-3e1sA:
3.1		 3gn0B-3e1sA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 GLY A 650
THR A 675
LEU A 467
ARG A 704
SER A 438
 None
 1.19A 3ndvA-3e1sA:
undetectable
3ndvB-3e1sA:
undetectable		 3ndvA-3e1sA:
22.63
3ndvB-3e1sA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 GLY A 650
THR A 675
LEU A 467
ARG A 704
SER A 438
 None
 1.24A 3ndvA-3e1sA:
undetectable
3ndvB-3e1sA:
undetectable		 3ndvA-3e1sA:
22.63
3ndvB-3e1sA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 GLY A 650
THR A 675
LEU A 467
ARG A 704
SER A 438
 None
 1.21A 3ndvC-3e1sA:
undetectable
3ndvD-3e1sA:
undetectable		 3ndvC-3e1sA:
22.63
3ndvD-3e1sA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 GLY A 650
THR A 675
LEU A 467
ARG A 704
SER A 438
 None
 1.19A 3ndvC-3e1sA:
undetectable
3ndvD-3e1sA:
undetectable		 3ndvC-3e1sA:
22.63
3ndvD-3e1sA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		6 / 12 LEU A 459
VAL A 384
GLY A 398
VAL A 400
VAL A 373
ILE A 433
 None
 1.25A 3nu5A-3e1sA:
undetectable		 3nu5A-3e1sA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		6 / 10 LEU A 459
VAL A 384
GLY A 398
VAL A 400
VAL A 373
ILE A 433
 None
 1.30A 3oxwD-3e1sA:
undetectable		 3oxwD-3e1sA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 ALA A 374
VAL A 373
LEU A 350
LEU A 432
 None
 0.81A 3roxA-3e1sA:
undetectable		 3roxA-3e1sA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 THR A 390
GLY A 391
THR A 606
GLY A 605
ASP A 623
 None
 1.12A 3t8nD-3e1sA:
undetectable
3t8nF-3e1sA:
undetectable		 3t8nD-3e1sA:
13.76
3t8nF-3e1sA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 ALA A 451
LEU A 315
ARG A 354
LEU A 308
PHE A 419
 None
 1.27A 3vhuA-3e1sA:
undetectable		 3vhuA-3e1sA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		3 / 3 GLY A 650
SER A 651
TRP A 653
 None
 0.80A 4e7cD-3e1sA:
undetectable		 4e7cD-3e1sA:
25.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 10 ARG A 336
ALA A 344
LEU A 339
GLY A 338
ALA A 405
 None
 1.16A 4fe1A-3e1sA:
undetectable
4fe1J-3e1sA:
undetectable		 4fe1A-3e1sA:
23.32
4fe1J-3e1sA:
5.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 10 GLN A 481
ALA A 480
ALA A 482
ALA A 483
LEU A 449
 None
 1.05A 4j6cB-3e1sA:
undetectable		 4j6cB-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 GLN A 481
ALA A 480
ALA A 482
ALA A 483
LEU A 449
 None
 1.00A 4j6dA-3e1sA:
undetectable		 4j6dA-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 GLN A 481
ALA A 480
ALA A 482
ALA A 483
LEU A 449
 None
 1.00A 4j6dB-3e1sA:
undetectable		 4j6dB-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 GLN A 481
ALA A 480
ALA A 482
ALA A 483
LEU A 449
 None
 1.03A 4jbtA-3e1sA:
undetectable		 4jbtA-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 11 GLN A 481
ALA A 480
ALA A 482
ALA A 483
LEU A 449
 None
 1.01A 4jbtB-3e1sA:
undetectable		 4jbtB-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 7 LEU A 558
ARG A 532
ARG A 533
SER A 691
 None
 1.25A 4klrA-3e1sA:
2.0		 4klrA-3e1sA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 LEU A 709
ILE A 312
VAL A 357
THR A 485
 None
 0.84A 4ma7A-3e1sA:
undetectable		 4ma7A-3e1sA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 LEU A 479
ALA A 483
LEU A 316
LEU A 315
GLY A 352
 None
 0.86A 4xi3C-3e1sA:
undetectable		 4xi3C-3e1sA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 LEU A 347
VAL A 346
LEU A 397
LEU A 358
GLU A 342
 None
 0.98A 4y0qA-3e1sA:
undetectable		 4y0qA-3e1sA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		6 / 10 ALA A 309
LEU A 283
LEU A 708
ALA A 707
LEU A 479
ALA A 478
 None
 1.30A 4zbrA-3e1sA:
undetectable		 4zbrA-3e1sA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 12 LEU A 311
LEU A 449
ILE A 433
ALA A 456
LEU A 431
 None
 1.12A 5ienB-3e1sA:
undetectable		 5ienB-3e1sA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 10 ALA A 687
THR A 523
GLU A 524
ALA A 531
GLY A 530
 None
 1.18A 5lf3H-3e1sA:
undetectable
5lf3I-3e1sA:
undetectable		 5lf3H-3e1sA:
19.22
5lf3I-3e1sA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		5 / 10 ALA A 687
THR A 523
GLU A 524
ALA A 531
GLY A 530
 None
 1.18A 5lf3V-3e1sA:
undetectable
5lf3W-3e1sA:
undetectable		 5lf3V-3e1sA:
19.22
5lf3W-3e1sA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 1.01A 5sxqA-3e1sA:
undetectable		 5sxqA-3e1sA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 0.96A 5sxqB-3e1sA:
undetectable		 5sxqB-3e1sA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 0.99A 5sxtA-3e1sA:
undetectable		 5sxtA-3e1sA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 0.97A 5sxtB-3e1sA:
undetectable		 5sxtB-3e1sA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 0.99A 5syjA-3e1sA:
undetectable		 5syjA-3e1sA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 8 GLU A 436
GLY A 360
GLN A 466
THR A 464
 None
 0.96A 5syjB-3e1sA:
2.5		 5syjB-3e1sA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 7 TYR A 414
PHE A 419
ALA A 443
GLY A 441
 None
 0.95A 5uxdA-3e1sA:
undetectable		 5uxdA-3e1sA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM7_A_ACTA603_0
(SALICYLATE-AMP
LIGASE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 4 THR A 314
THR A 318
ALA A 317
ARG A 354
 None
 1.29A 5wm7A-3e1sA:
0.8		 5wm7A-3e1sA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 5 GLN A 466
THR A 464
THR A 489
LEU A 508
 None
 1.15A 6aphA-3e1sA:
2.1		 6aphA-3e1sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYN_A_HSMA901_0
(EBONY)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 4 GLU A 378
VAL A 384
LEU A 386
THR A 401
 None
 1.19A 6dynA-3e1sA:
0.4		 6dynA-3e1sA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 5 GLU A 378
VAL A 384
LEU A 386
THR A 401
 None
 1.22A 6dyoA-3e1sA:
undetectable		 6dyoA-3e1sA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 4 GLN A 466
THR A 464
THR A 489
LEU A 508
 None
 1.16A 6f3mA-3e1sA:
3.5		 6f3mA-3e1sA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 4 GLN A 466
THR A 464
THR A 489
LEU A 508
 None
 1.16A 6f3mC-3e1sA:
2.2		 6f3mC-3e1sA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 3e1s EXODEOXYRIBONUCLEASE
V, SUBUNIT RECD
(Deinococcus
radiodurans) 		4 / 5 GLN A 466
THR A 464
THR A 489
LEU A 508
 None
 1.20A 6gbnB-3e1sA:
2.3		 6gbnB-3e1sA:
23.63