SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e21'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3e21 FAS-ASSOCIATED
FACTOR 1
(Homo
sapiens) 		5 / 11 ILE A  10
ALA A  12
GLN A  15
LEU A  30
ALA A  26
 None
 1.18A 4nqaA-3e21A:
undetectable		 4nqaA-3e21A:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3e21 FAS-ASSOCIATED
FACTOR 1
(Homo
sapiens) 		4 / 6 LEU A  11
ILE A  10
LEU A  30
GLU A  31
 None
 0.95A 4w5nA-3e21A:
undetectable		 4w5nA-3e21A:
4.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3e21 FAS-ASSOCIATED
FACTOR 1
(Homo
sapiens) 		5 / 10 ILE A  10
ILE A  23
ALA A  26
ILE A  27
ILE A  20
 None
 0.99A 5mvmD-3e21A:
undetectable
5mvmE-3e21A:
undetectable		 5mvmD-3e21A:
24.00
5mvmE-3e21A:
24.00