SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 ASP A 273
HIS A 277
HIS A 316
HIS A 465
 ZN  A 601 ( 2.1A)
ZN  A 601 (-3.2A)
ZN  A 602 ( 3.2A)
ZN  A 601 ( 3.2A)
 0.37A 1ei6A-3e2dA:
16.3		 1ei6A-3e2dA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 8 ASP A  12
ASP A 273
HIS A 277
HIS A 316
HIS A 465
 ZN  A 602 (-2.2A)
ZN  A 601 ( 2.1A)
ZN  A 601 (-3.2A)
ZN  A 602 ( 3.2A)
ZN  A 601 ( 3.2A)
 0.42A 1ei6C-3e2dA:
15.9		 1ei6C-3e2dA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		6 / 11 SER A  53
GLU A 492
TYR A  77
GLY A 494
LEU A 493
VAL A  63
 None
 1.44A 1i9jH-3e2dA:
undetectable
1i9jL-3e2dA:
undetectable		 1i9jH-3e2dA:
17.86
1i9jL-3e2dA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 10 HIS A 128
ALA A 120
ALA A 124
GLN A 126
ILE A 135
 None
 1.06A 1likA-3e2dA:
undetectable		 1likA-3e2dA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 GLY A  89
GLN A  88
VAL A  92
SER A  78
 None
 1.39A 1p6kB-3e2dA:
undetectable		 1p6kB-3e2dA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 GLY A  89
GLN A  88
VAL A  92
SER A  78
 None
 1.41A 1rs6B-3e2dA:
undetectable		 1rs6B-3e2dA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 279
LEU A 448
ALA A 449
GLN A 452
THR A 318
 None
None
None
None
ZN  A 601 ( 4.3A)
 1.17A 1ya3A-3e2dA:
undetectable		 1ya3A-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASP A 443
HIS A 465
HIS A 277
ASP A  12
GLY A  13
 None
ZN  A 601 ( 3.2A)
ZN  A 601 (-3.2A)
ZN  A 602 (-2.2A)
None
 1.06A 1zz1C-3e2dA:
2.3		 1zz1C-3e2dA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 GLY A  89
GLN A  88
VAL A  92
SER A  78
 None
 1.40A 1zzuB-3e2dA:
undetectable		 1zzuB-3e2dA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 279
LEU A 448
ALA A 449
GLN A 452
THR A 318
 None
None
None
None
ZN  A 601 ( 4.3A)
 1.15A 2aa5A-3e2dA:
undetectable		 2aa5A-3e2dA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 446
LEU A 448
ALA A 449
GLN A 452
PHE A 439
 None
 1.25A 2oaxB-3e2dA:
undetectable		 2oaxB-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 446
LEU A 448
ALA A 449
GLN A 452
PHE A 439
 None
 1.23A 2oaxD-3e2dA:
undetectable		 2oaxD-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 446
LEU A 448
ALA A 449
GLN A 452
PHE A 439
 None
 1.23A 2oaxE-3e2dA:
undetectable		 2oaxE-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 279
LEU A 448
ALA A 449
GLN A 452
THR A 318
 None
None
None
None
ZN  A 601 ( 4.3A)
 1.14A 2oaxF-3e2dA:
undetectable		 2oaxF-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASN A 446
LEU A 448
ALA A 449
GLN A 452
PHE A 439
 None
 1.28A 2oaxF-3e2dA:
undetectable		 2oaxF-3e2dA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 7 SER A 373
GLN A 364
ILE A 391
SER A 367
 None
 1.22A 2xz5A-3e2dA:
undetectable
2xz5B-3e2dA:
undetectable		 2xz5A-3e2dA:
19.96
2xz5B-3e2dA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 8 HIS A 465
HIS A 277
ASP A  12
GLY A  13
 ZN  A 601 ( 3.2A)
ZN  A 601 (-3.2A)
ZN  A 602 (-2.2A)
None
 0.89A 3c0zB-3e2dA:
3.1		 3c0zB-3e2dA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 7 GLY A  11
HIS A 316
ASP A  12
GLN A  18
 None
ZN  A 602 ( 3.2A)
ZN  A 602 (-2.2A)
None
 0.90A 3fi0P-3e2dA:
undetectable		 3fi0P-3e2dA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 SER A  68
HIS A 490
VAL A  92
ILE A  85
HIS A 489
 None
 1.16A 3g9eA-3e2dA:
undetectable		 3g9eA-3e2dA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		3 / 3 SER A  79
ASP A  59
ASP A  86
 None
EDO  A 622 (-4.6A)
None
 0.85A 3iv6A-3e2dA:
undetectable		 3iv6A-3e2dA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		3 / 3 SER A  79
ASP A  59
ASP A  86
 None
EDO  A 622 (-4.6A)
None
 0.85A 3iv6C-3e2dA:
2.1		 3iv6C-3e2dA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 PHE A 323
LEU A 288
LEU A 285
MET A 284
PHE A 321
 None
 1.04A 3lbdA-3e2dA:
undetectable		 3lbdA-3e2dA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 HIS A 316
SER A  65
THR A 118
ASP A 443
 ZN  A 602 ( 3.2A)
ZN  A 602 (-3.5A)
MG  A 603 (-3.0A)
None
 1.21A 3tm4A-3e2dA:
2.0		 3tm4A-3e2dA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 HIS A 316
SER A  65
THR A 118
ASP A 443
 ZN  A 602 ( 3.2A)
ZN  A 602 (-3.5A)
MG  A 603 (-3.0A)
None
 1.18A 3tm4B-3e2dA:
undetectable		 3tm4B-3e2dA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 7 GLY A 269
ASP A  12
GLY A  11
HIS A 316
 None
ZN  A 602 (-2.2A)
None
ZN  A 602 ( 3.2A)
 0.89A 4c5nA-3e2dA:
undetectable		 4c5nA-3e2dA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 8 GLY A 269
ASP A  12
GLY A  11
HIS A 316
 None
ZN  A 602 (-2.2A)
None
ZN  A 602 ( 3.2A)
 0.89A 4c5nC-3e2dA:
undetectable		 4c5nC-3e2dA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		3 / 3 ARG A 153
LYS A 181
LYS A 183
 None
 1.45A 4k50A-3e2dA:
undetectable		 4k50A-3e2dA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		3 / 3 ARG A 153
LYS A 181
LYS A 183
 None
 1.37A 4k50E-3e2dA:
undetectable		 4k50E-3e2dA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 SER A  65
GLY A 269
THR A 118
ASP A 111
ILE A 272
 ZN  A 602 (-3.5A)
None
MG  A 603 (-3.0A)
None
None
 1.36A 4pghB-3e2dA:
undetectable		 4pghB-3e2dA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		3 / 3 ASP A 280
GLY A 445
ASP A 443
 None
 0.42A 4xdtA-3e2dA:
undetectable		 4xdtA-3e2dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 10 LEU A 191
ALA A 194
GLU A 193
LEU A 140
ARG A 188
 None
 1.23A 5hyrA-3e2dA:
undetectable		 5hyrA-3e2dA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 11 VAL A 109
SER A 110
ASP A 111
THR A 112
LEU A 265
 None
None
None
MG  A 603 ( 4.8A)
None
 1.04A 5jh7B-3e2dA:
2.0		 5jh7B-3e2dA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 11 VAL A 109
SER A 110
ASP A 111
THR A 112
LEU A 265
 None
None
None
MG  A 603 ( 4.8A)
None
 1.14A 5jh7D-3e2dA:
2.1		 5jh7D-3e2dA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 4 LEU A 265
MET A 147
ILE A 497
LEU A  96
 None
 1.40A 5nfpA-3e2dA:
undetectable		 5nfpA-3e2dA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 7 ASP A  12
GLY A 270
ASP A 315
HIS A 277
ASP A 273
 ZN  A 602 (-2.2A)
MG  A 603 ( 4.5A)
ZN  A 602 (-2.4A)
ZN  A 601 (-3.2A)
ZN  A 601 ( 2.1A)
 1.43A 5nnwD-3e2dA:
undetectable		 5nnwD-3e2dA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 7 ASP A  12
GLY A 270
ASP A 315
HIS A 277
ASP A 273
 ZN  A 602 (-2.2A)
MG  A 603 ( 4.5A)
ZN  A 602 (-2.4A)
ZN  A 601 (-3.2A)
ZN  A 601 ( 2.1A)
 1.47A 5no9D-3e2dA:
undetectable		 5no9D-3e2dA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 12 ASP A 259
LEU A 493
ILE A  10
ALA A  69
ALA A 123
 None
 1.18A 5vc0A-3e2dA:
undetectable		 5vc0A-3e2dA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 7 GLN A  17
GLY A 319
GLN A 364
TRP A 460
ASP A  12
 None
None
None
None
ZN  A 602 (-2.2A)
 1.47A 5vlmE-3e2dA:
3.4		 5vlmE-3e2dA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 LEU A 208
PHE A 203
PHE A 220
LEU A 148
 None
 1.13A 5x1bP-3e2dA:
undetectable		 5x1bP-3e2dA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 6 HIS A 490
ASN A 471
VAL A 312
LEU A   8
 None
 0.97A 5xdhA-3e2dA:
undetectable
5xdhC-3e2dA:
undetectable		 5xdhA-3e2dA:
10.39
5xdhC-3e2dA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 HIS A 490
ASN A 471
VAL A 312
LEU A   8
 None
 0.91A 5xdhB-3e2dA:
undetectable		 5xdhB-3e2dA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 6 HIS A 490
ASN A 471
VAL A 312
LEU A   8
 None
 1.11A 5xdhA-3e2dA:
undetectable
5xdhC-3e2dA:
undetectable		 5xdhA-3e2dA:
10.39
5xdhC-3e2dA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 HIS A 490
ASN A 471
VAL A 312
LEU A   8
 None
 1.02A 5xdhD-3e2dA:
undetectable		 5xdhD-3e2dA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		5 / 11 SER A  65
ARG A 129
ALA A  69
THR A 115
LEU A 114
 ZN  A 602 (-3.5A)
SO4  A 610 (-3.0A)
None
None
None
 1.26A 6efnA-3e2dA:
undetectable		 6efnA-3e2dA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 4 MET A  14
GLY A  13
HIS A 316
GLY A  15
 None
None
ZN  A 602 ( 3.2A)
None
 1.34A 6fgdA-3e2dA:
undetectable		 6fgdA-3e2dA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 GLN A  18
THR A 112
HIS A 116
GLY A 276
 None
MG  A 603 ( 4.8A)
SO4  A 610 ( 4.8A)
None
 1.22A 6gbnC-3e2dA:
undetectable		 6gbnC-3e2dA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3e2d ALKALINE PHOSPHATASE
(Vibrio
sp.
G15-21) 		4 / 5 TYR A 199
VAL A 178
MET A 139
GLY A 143
 None
SO4  A 611 ( 3.7A)
None
None
 1.37A 6hd4A-3e2dA:
undetectable		 6hd4A-3e2dA:
12.33