SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		4 / 6 HIS A 206
LEU A 264
LEU A 268
PRO A 149
 None
 1.11A 1hz4A-3e35A:
undetectable		 1hz4A-3e35A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		4 / 5 PRO A  77
VAL A  70
TYR A  89
GLU A  91
 None
 1.41A 1m8dA-3e35A:
0.0		 1m8dA-3e35A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		4 / 5 PRO A  77
VAL A  70
TYR A  89
GLU A  91
 None
 1.42A 1m8dB-3e35A:
0.0		 1m8dB-3e35A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 LEU A 232
PHE A 107
SER A  55
PRO A  57
VAL A  49
 None
 1.10A 1u72A-3e35A:
undetectable		 1u72A-3e35A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 11 ILE A 224
ALA A 227
ALA A 226
ARG A 136
ILE A 235
 None
 1.11A 2aclE-3e35A:
undetectable		 2aclE-3e35A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		6 / 11 SER A 138
MET A  31
VAL A  18
GLY A 127
ILE A 129
VAL A  61
 None
 1.42A 2uxpB-3e35A:
undetectable		 2uxpB-3e35A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 GLU A 222
GLY A 234
ALA A 236
ASP A 101
ALA A 102
 None
 1.28A 3nmuA-3e35A:
undetectable
3nmuF-3e35A:
undetectable		 3nmuA-3e35A:
22.33
3nmuF-3e35A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		4 / 7 ARG A  63
ILE A 129
PHE A  64
LEU A 110
 None
 1.09A 4mmcA-3e35A:
undetectable		 4mmcA-3e35A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 9 LEU A 232
ASP A 101
GLY A 104
ALA A 105
THR A 225
 None
 1.13A 4njtD-3e35A:
undetectable		 4njtD-3e35A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 LEU A 221
ILE A 156
GLY A 155
LEU A 239
ALA A 217
 None
 1.01A 5h5fA-3e35A:
undetectable		 5h5fA-3e35A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 ILE A 129
GLY A 127
VAL A 186
PHE A 122
ALA A  62
 None
 1.16A 5n0oA-3e35A:
undetectable		 5n0oA-3e35A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 ILE A 129
GLY A 127
VAL A 186
PHE A 122
ALA A  62
 None
 1.14A 5n0rA-3e35A:
undetectable		 5n0rA-3e35A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3e35 UNCHARACTERIZED
PROTEIN SCO1997
(Streptomyces
coelicolor) 		5 / 12 ILE A 129
GLY A 127
VAL A 186
PHE A 122
ALA A  62
 None
 1.16A 5n0wA-3e35A:
undetectable		 5n0wA-3e35A:
23.22