SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 7 THR X 252
GLY X 257
LEU X 259
TYR X 308
 None
 1.01A 1gtiE-3e3bX:
undetectable		 1gtiE-3e3bX:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 7 LYS X  69
LEU X  86
ILE X  95
ILE X 153
 CCK  X 351 (-3.5A)
None
None
None
 0.82A 1uwjA-3e3bX:
5.8		 1uwjA-3e3bX:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 LEU X 172
PRO X 160
VAL X 163
ILE X 165
 None
 0.87A 2aoiB-3e3bX:
undetectable		 2aoiB-3e3bX:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 THR X 109
PRO X 105
PRO X 110
 None
 0.79A 2d55C-3e3bX:
undetectable		 2d55C-3e3bX:
2.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		7 / 12 LEU X  46
GLY X  47
VAL X  54
ASP X 157
LYS X 159
ASN X 162
MET X 164
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.9A)
CCK  X 351 ( 4.3A)
None
None
None
CCK  X 351 (-3.5A)
 0.84A 2fumA-3e3bX:
24.0		 2fumA-3e3bX:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		7 / 12 LEU X  46
GLY X  47
VAL X  54
TYR X 116
LYS X 159
ASN X 162
MET X 164
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.9A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-4.3A)
None
None
CCK  X 351 (-3.5A)
 0.95A 2fumB-3e3bX:
24.0		 2fumB-3e3bX:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		7 / 12 LEU X  46
GLY X  47
GLY X  49
VAL X  54
LYS X 159
ASN X 162
MET X 164
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.9A)
None
CCK  X 351 ( 4.3A)
None
None
CCK  X 351 (-3.5A)
 0.90A 2fumD-3e3bX:
14.8		 2fumD-3e3bX:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 ASP X  26
TYR X  27
LYS X  80
 None
 1.19A 2othA-3e3bX:
undetectable		 2othA-3e3bX:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 LEU X 214
MET X 154
MET X 138
 None
 0.51A 2vavF-3e3bX:
undetectable		 2vavF-3e3bX:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 12 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.08A 2yjaB-3e3bX:
undetectable		 2yjaB-3e3bX:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 LEU X  89
LEU X  86
ARG X  81
 None
 0.72A 3hcnB-3e3bX:
undetectable		 3hcnB-3e3bX:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 12 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.06A 3olsA-3e3bX:
undetectable		 3olsA-3e3bX:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 8 TYR X  13
TYR X 212
LEU X  89
TRP X 177
 None
 1.44A 3uzzB-3e3bX:
undetectable		 3uzzB-3e3bX:
23.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 VAL X  54
ILE X  96
PHE X 114
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 0.90A 3warA-3e3bX:
47.8		 3warA-3e3bX:
85.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 8 VAL X  54
LYS X  69
ILE X  96
PHE X 114
MET X 164
 CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
 0.70A 3warA-3e3bX:
47.8		 3warA-3e3bX:
85.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 VAL X  54
VAL X  67
ILE X  96
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 0.82A 3warA-3e3bX:
47.8		 3warA-3e3bX:
85.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 8 VAL X  54
VAL X  67
LYS X  69
ILE X  96
MET X 164
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.5A)
 0.65A 3warA-3e3bX:
47.8		 3warA-3e3bX:
85.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 8 TRP X  25
ARG X  20
GLU X  15
HIS X 184
 None
 1.24A 3zmdA-3e3bX:
undetectable
3zmdB-3e3bX:
undetectable		 3zmdA-3e3bX:
20.96
3zmdB-3e3bX:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 9 ILE X  85
LEU X  89
ILE X  95
ILE X  96
TYR X 116
 None
None
None
CCK  X 351 ( 4.6A)
CCK  X 351 (-4.3A)
 0.70A 3zosA-3e3bX:
12.1		 3zosA-3e3bX:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 9 LEU X  46
ILE X  85
LEU X  89
ILE X  95
TYR X 116
 CCK  X 351 (-4.0A)
None
None
None
CCK  X 351 (-4.3A)
 0.84A 3zosB-3e3bX:
11.9		 3zosB-3e3bX:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 HIS X 149
LEU X 306
LEU X 223
ASP X 303
 None
 1.03A 4aqlA-3e3bX:
undetectable		 4aqlA-3e3bX:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 LYS X  69
LEU X  89
TYR X 116
ARG X 156
 CCK  X 351 (-3.5A)
None
CCK  X 351 (-4.3A)
None
 1.10A 4bkjB-3e3bX:
5.2		 4bkjB-3e3bX:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 HIS X 310
TRP X 217
SER X   8
 None
 1.21A 4lrhD-3e3bX:
undetectable		 4lrhD-3e3bX:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 PHE X 285
PHE X 234
PHE X 233
VAL X 249
 None
 1.00A 5a1rA-3e3bX:
undetectable		 5a1rA-3e3bX:
22.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 5 ARG X  81
ARG X 156
LEU X 179
ASN X 190
VAL X 193
 None
 0.76A 5cshB-3e3bX:
46.1		 5cshB-3e3bX:
80.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CU6_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 4 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.76A 5cu6A-3e3bX:
46.9		 5cu6A-3e3bX:
84.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 6 TYR X  40
ILE X  70
VAL X 102
ALA X 111
 None
 0.50A 5cu6A-3e3bX:
46.9		 5cu6A-3e3bX:
84.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 6 TYR X  40
VAL X 102
PRO X 105
ALA X 111
 None
 0.86A 5cu6A-3e3bX:
46.9		 5cu6A-3e3bX:
84.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CVF_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 4 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.75A 5cvfA-3e3bX:
46.5		 5cvfA-3e3bX:
84.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 10 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.08A 5dx3A-3e3bX:
undetectable		 5dx3A-3e3bX:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 10 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.06A 5dxbA-3e3bX:
undetectable		 5dxbA-3e3bX:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 11 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.11A 5dxbB-3e3bX:
undetectable		 5dxbB-3e3bX:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 11 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.13A 5dxgB-3e3bX:
undetectable		 5dxgB-3e3bX:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		3 / 3 ASP X 166
ARG X  44
ARG X  65
 None
CCK  X 351 (-4.6A)
None
 0.91A 5eajB-3e3bX:
undetectable		 5eajB-3e3bX:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 12 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.11A 5gtrA-3e3bX:
undetectable		 5gtrA-3e3bX:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 7 ILE X  85
GLU X 181
ASP X  26
ASN X  17
 None
 1.05A 5n5dA-3e3bX:
undetectable		 5n5dA-3e3bX:
20.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 4 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.78A 5os7A-3e3bX:
39.7		 5os7A-3e3bX:
80.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 5 ARG X  81
ARG X 156
LEU X 179
ASN X 190
VAL X 193
 None
 0.77A 5os7B-3e3bX:
46.7		 5os7B-3e3bX:
80.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS8_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 5 LYS X  78
ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.92A 5os8A-3e3bX:
46.5		 5os8A-3e3bX:
84.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSP_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 4 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.76A 5ospA-3e3bX:
46.6		 5ospA-3e3bX:
83.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 7 TYR X  40
VAL X  68
ILE X  70
VAL X 102
ALA X 111
 None
 0.54A 5ospA-3e3bX:
46.6		 5ospA-3e3bX:
83.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.77A 5osrA-3e3bX:
46.1		 5osrA-3e3bX:
83.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 7 TYR X  40
VAL X  68
ILE X  70
VAL X 102
ALA X 111
 None
 0.46A 5osrA-3e3bX:
46.1		 5osrA-3e3bX:
83.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OTR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.74A 5otrA-3e3bX:
45.7		 5otrA-3e3bX:
83.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 5 TYR X  40
VAL X 102
PRO X 105
ALA X 111
 None
 0.86A 5otrA-3e3bX:
45.7		 5otrA-3e3bX:
83.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 9 ALA X 319
GLU X 318
LEU X 314
ARG X  11
GLY X 220
 None
 1.12A 5wgqA-3e3bX:
undetectable		 5wgqA-3e3bX:
11.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 LEU X  46
VAL X  54
VAL X  67
LYS X  69
PHE X 114
ILE X 175
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
 1.01A 5y9mA-3e3bX:
36.1		 5y9mA-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 LEU X  46
VAL X  54
VAL X  67
PHE X 114
ILE X 175
ASP X 176
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.07A 5y9mA-3e3bX:
36.1		 5y9mA-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 VAL X  54
VAL X  67
LYS X  69
PHE X 114
MET X 164
ILE X 175
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
 1.03A 5y9mA-3e3bX:
36.1		 5y9mA-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 8 VAL X  54
VAL X  67
PHE X 114
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.09A 5y9mA-3e3bX:
36.1		 5y9mA-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 8 VAL X  54
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 0.69A 5y9mX-3e3bX:
46.7		 5y9mX-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 7 VAL X  54
VAL X  67
LYS X  69
PHE X 114
MET X 164
ILE X 175
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
 1.05A 5yf9B-3e3bX:
46.8		 5yf9B-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 7 VAL X  54
VAL X  67
PHE X 114
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.09A 5yf9B-3e3bX:
46.8		 5yf9B-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 9 LEU X  46
VAL X  54
VAL X  67
LYS X  69
PHE X 114
ILE X 175
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
 1.00A 5yf9X-3e3bX:
46.8		 5yf9X-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		7 / 9 LEU X  46
VAL X  54
VAL X  67
PHE X 114
MET X 164
ILE X 175
ASP X 176
 CCK  X 351 (-4.0A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.5A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.13A 5yf9X-3e3bX:
46.8		 5yf9X-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 9 VAL X  54
VAL X  67
ILE X  96
PHE X 114
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.04A 5yf9X-3e3bX:
46.8		 5yf9X-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 9 VAL X  54
VAL X  67
LYS X  69
ILE X  96
PHE X 114
ILE X 175
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
 0.93A 5yf9X-3e3bX:
46.8		 5yf9X-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 7 VAL X  54
VAL X  67
ILE X  96
PHE X 114
ILE X 175
ASP X 176
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
CCK  X 351 (-4.1A)
 1.04A 5ywmX-3e3bX:
40.8		 5ywmX-3e3bX:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		6 / 7 VAL X  54
VAL X  67
LYS X  69
ILE X  96
PHE X 114
ILE X 175
 CCK  X 351 ( 4.3A)
CCK  X 351 ( 4.3A)
CCK  X 351 (-3.5A)
CCK  X 351 ( 4.6A)
CCK  X 351 (-3.8A)
CCK  X 351 (-3.9A)
 0.88A 5ywmX-3e3bX:
40.8		 5ywmX-3e3bX:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 10 LEU X 305
ALA X 319
GLU X 283
SER X 295
ARG X 135
 None
 1.48A 6b89B-3e3bX:
0.4		 6b89B-3e3bX:
11.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		5 / 5 ARG X  81
ARG X 156
LEU X 179
ASN X 190
VAL X 193
 None
 0.77A 6gmdA-3e3bX:
46.7		 6gmdA-3e3bX:
80.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3e3b CASEIN KINASE II
SUBUNIT ALPHA'
(Homo
sapiens) 		4 / 4 ARG X  81
ARG X 156
LEU X 179
ASN X 190
 None
 0.78A 6gmdB-3e3bX:
39.7		 6gmdB-3e3bX:
80.97