SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e3c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ARG A  -2
VAL A  -4
SER A  81
LYS A   4
 None
 1.21A 1hwiC-3e3cA:
undetectable		 1hwiC-3e3cA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ARG A  -2
VAL A  -4
SER A  81
LYS A   4
 None
 1.21A 1hwiD-3e3cA:
undetectable		 1hwiD-3e3cA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 8 ARG A  -2
VAL A  -4
SER A  81
LYS A   4
 None
 1.22A 1hwkA-3e3cA:
undetectable		 1hwkA-3e3cA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 8 ARG A  -2
VAL A  -4
SER A  81
LYS A   4
 None
 1.20A 1hwkC-3e3cA:
undetectable		 1hwkC-3e3cA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 8 ARG A  -2
VAL A  -4
SER A  81
LYS A   4
 None
 1.21A 1hwkD-3e3cA:
undetectable		 1hwkD-3e3cA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3e3c L0044
(Escherichia
coli) 		4 / 6 TYR A  40
VAL A  54
TYR A  71
ASP A  35
 HHG  A 150 (-3.7A)
None
HHG  A 150 (-4.6A)
HHG  A 150 (-3.5A)
 1.34A 2x45A-3e3cA:
3.4		 2x45A-3e3cA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ILE A  25
LEU A  24
GLY A  34
GLY A  33
 None
HHG  A 150 (-4.9A)
None
None
 0.78A 5a06A-3e3cA:
undetectable		 5a06A-3e3cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ILE A  25
LEU A  24
GLY A  34
GLY A  33
 None
HHG  A 150 (-4.9A)
None
None
 0.77A 5a06B-3e3cA:
undetectable		 5a06B-3e3cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ILE A  25
LEU A  24
GLY A  34
GLY A  33
 None
HHG  A 150 (-4.9A)
None
None
 0.77A 5a06C-3e3cA:
undetectable		 5a06C-3e3cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ILE A  25
LEU A  24
GLY A  34
GLY A  33
 None
HHG  A 150 (-4.9A)
None
None
 0.77A 5a06E-3e3cA:
undetectable		 5a06E-3e3cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e3c L0044
(Escherichia
coli) 		4 / 7 ILE A  25
LEU A  24
GLY A  34
GLY A  33
 None
HHG  A 150 (-4.9A)
None
None
 0.78A 5a06F-3e3cA:
undetectable		 5a06F-3e3cA:
17.21