SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_D_ACHD1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3e3r	CALCYPHOSIN (Homo sapiens)	4 / 8	THR A 114 GLN A 156 ASP A 117 SER A 108	CA A 196 ( 4.7A) None CA A 196 (-2.4A) CA A 196 (-2.5A)	1.03A	2xz5C-3e3rA: undetectable 2xz5D-3e3rA: undetectable	2xz5C-3e3rA: 19.67 2xz5D-3e3rA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDC_A_ASDA404_1 (3-KETOSTEROID 9ALPHA-HYDROXYLASE OXYGENASE)	3e3r	CALCYPHOSIN (Homo sapiens)	5 / 12	VAL A 97 MET A 90 SER A 91 ALA A 93 ASP A 176	None	1.37A	4qdcA-3e3rA: undetectable	4qdcA-3e3rA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	3e3r	CALCYPHOSIN (Homo sapiens)	5 / 12	PHE A 82 ALA A 85 ARG A 12 LEU A 11 LEU A 33	None	1.33A	4qzuA-3e3rA: undetectable	4qzuA-3e3rA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_1 (SCRFP-TAG,GP41)	3e3r	CALCYPHOSIN (Homo sapiens)	5 / 12	GLY A 73 SER A 74 GLU A 81 LEU A 83 LEU A 77	None CA A 192 (-2.5A) CA A 192 (-2.3A) None None	1.06A	5nwwA-3e3rA: undetectable	5nwwA-3e3rA: 14.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XZ5_D_ACHD1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","3e3r","CALCYPHOSIN","Homo sapiens",4,"THR A 114;GLN A 156;ASP A 117;SER A 108"," CA A 196 ( 4.7A);None; CA A 196 (-2.4A); CA A 196 (-2.5A)","1.03A","2xz5C-3e3rA:undetectable;2xz5D-3e3rA:undetectable","2xz5C-3e3rA:19.67;2xz5D-3e3rA:19.67"],["4QDC_A_ASDA404_1","3-KETOSTEROID 9ALPHA-HYDROXYLASE OXYGENASE","3e3r","CALCYPHOSIN","Homo sapiens",5,"VAL A  97;MET A  90;SER A  91;ALA A  93;ASP A 176","None","1.37A","4qdcA-3e3rA:undetectable","4qdcA-3e3rA:21.45"],["4QZU_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","3e3r","CALCYPHOSIN","Homo sapiens",5,"PHE A  82;ALA A  85;ARG A  12;LEU A  11;LEU A  33","None","1.33A","4qzuA-3e3rA:undetectable","4qzuA-3e3rA:20.00"],["5NWW_A_ACAA18_1","SCRFP-TAG,GP41","3e3r","CALCYPHOSIN","Homo sapiens",5,"GLY A  73;SER A  74;GLU A  81;LEU A  83;LEU A  77","None; CA A 192 (-2.5A); CA A 192 (-2.3A);None;None","1.06A","5nwwA-3e3rA:undetectable","5nwwA-3e3rA:14.12"]]