SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e4b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3e4b ALGK
(Pseudomonas
fluorescens) 		5 / 12 LEU A  29
LEU A  32
GLY A  33
MET A 114
LEU A  41
 None
 0.66A 1gs4A-3e4bA:
undetectable		 1gs4A-3e4bA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3e4b ALGK
(Pseudomonas
fluorescens) 		3 / 3 ALA A 301
VAL A 299
TRP A 298
 None
 0.97A 1tkqA-3e4bA:
undetectable		 1tkqA-3e4bA:
3.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 3e4b ALGK
(Pseudomonas
fluorescens) 		5 / 12 VAL A 222
LEU A  32
TYR A  34
GLN A 214
GLU A 181
 None
 1.49A 2no0A-3e4bA:
undetectable		 2no0A-3e4bA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3e4b ALGK
(Pseudomonas
fluorescens) 		5 / 12 LEU A  29
LEU A  32
GLY A  33
ALA A  37
LEU A  41
 None
 0.85A 2oz7A-3e4bA:
undetectable		 2oz7A-3e4bA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3e4b ALGK
(Pseudomonas
fluorescens) 		5 / 12 LEU A  29
LEU A  32
GLY A  33
MET A 114
LEU A  41
 None
 0.81A 2oz7A-3e4bA:
undetectable		 2oz7A-3e4bA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 3e4b ALGK
(Pseudomonas
fluorescens) 		4 / 6 GLN A 269
ASP A 275
GLU A 286
LEU A 254
 None
 1.14A 4ax8A-3e4bA:
undetectable		 4ax8A-3e4bA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3e4b ALGK
(Pseudomonas
fluorescens) 		4 / 8 TYR A  34
THR A 175
LEU A 145
GLY A 144
 None
 0.88A 4c9nA-3e4bA:
undetectable		 4c9nA-3e4bA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3e4b ALGK
(Pseudomonas
fluorescens) 		4 / 5 LEU A 223
SER A 218
LEU A 240
LEU A 199
 None
 1.20A 4n09B-3e4bA:
undetectable		 4n09B-3e4bA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 3e4b ALGK
(Pseudomonas
fluorescens) 		4 / 5 LEU A 223
SER A 218
LEU A 240
LEU A 199
 None
 1.21A 4n09D-3e4bA:
undetectable		 4n09D-3e4bA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3e4b ALGK
(Pseudomonas
fluorescens) 		4 / 7 ARG A 208
THR A 210
GLN A 201
GLY A 205
 None
 0.98A 5nzyA-3e4bA:
undetectable		 5nzyA-3e4bA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3e4b ALGK
(Pseudomonas
fluorescens) 		5 / 12 LEU A  41
GLY A  40
VAL A 180
ILE A 177
ASP A 176
 None
 1.25A 6bxnB-3e4bA:
undetectable		 6bxnB-3e4bA:
22.13