SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3e4v NADH:FMN
OXIDOREDUCTASE LIKE
PROTEIN
(Methylobacillus
flagellatus) 		3 / 4 VAL A  73
TRP A 145
TRP A 118
 None
 1.38A 1gmkC-3e4vA:
undetectable
1gmkD-3e4vA:
undetectable		 1gmkC-3e4vA:
10.22
1gmkD-3e4vA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3e4v NADH:FMN
OXIDOREDUCTASE LIKE
PROTEIN
(Methylobacillus
flagellatus) 		5 / 11 ILE A 144
ALA A  10
VAL A 141
VAL A  20
LEU A 113
 None
 1.20A 1n4hA-3e4vA:
undetectable		 1n4hA-3e4vA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3e4v NADH:FMN
OXIDOREDUCTASE LIKE
PROTEIN
(Methylobacillus
flagellatus) 		3 / 3 ASN A  87
ASP A 161
GLY A 160
 FMN  A 300 ( 4.5A)
None
None
 0.61A 5fctB-3e4vA:
undetectable		 5fctB-3e4vA:
20.70