SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		6 / 12 VAL A  94
ILE A   5
ILE A 165
ASP A  90
VAL A  91
LEU A  13
 None
 1.25A 1qhyA-3e58A:
undetectable		 1qhyA-3e58A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.86A 1usqA-3e58A:
undetectable		 1usqA-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 6 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.85A 1usqD-3e58A:
undetectable		 1usqD-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 6 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.84A 1usqE-3e58A:
undetectable		 1usqE-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 GLY A  46
SER A  41
SER A 168
GLU A 169
 None
 0.96A 2c8aB-3e58A:
undetectable		 2c8aB-3e58A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 GLY A  46
SER A  41
SER A 168
GLU A 169
 None
 0.97A 2c8aD-3e58A:
undetectable		 2c8aD-3e58A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.87A 2jklA-3e58A:
undetectable		 2jklA-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.87A 2jklD-3e58A:
undetectable		 2jklD-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 7 PRO A 143
GLY A 171
ILE A  44
GLY A  45
 None
 0.87A 2jklF-3e58A:
undetectable		 2jklF-3e58A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		4 / 6 ARG A  23
ASP A 115
ILE A 116
GLU A 136
 None
 1.43A 2ya7C-3e58A:
undetectable		 2ya7C-3e58A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		5 / 12 ALA A 119
GLY A  11
ILE A 116
SER A 111
ARG A  23
 None
GOL  A 303 (-3.6A)
None
None
None
 1.27A 3gyqA-3e58A:
4.4
3gyqB-3e58A:
4.4		 3gyqA-3e58A:
24.28
3gyqB-3e58A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		3 / 3 SER A 110
ASP A   8
ASP A 115
 SO4  A 301 ( 4.6A)
None
None
 0.85A 3iv6A-3e58A:
2.9		 3iv6A-3e58A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3e58 PUTATIVE
BETA-PHOSPHOGLUCOMUT
ASE
(Streptococcus
thermophilus) 		3 / 3 SER A 110
ASP A   8
ASP A 115
 SO4  A 301 ( 4.6A)
None
None
 0.90A 3iv6C-3e58A:
2.9		 3iv6C-3e58A:
23.88