SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 12 PHE A  24
LEU A  44
ALA A  26
LEU A  91
PHE A  19
 None
 1.11A 1og5A-3e5dA:
undetectable		 1og5A-3e5dA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 12 PHE A  24
LEU A  44
ALA A  26
LEU A  91
PHE A  19
 None
 1.12A 1og5B-3e5dA:
undetectable		 1og5B-3e5dA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		3 / 3 SER A 112
GLU A  89
ASP A  94
 None
 0.83A 2avdB-3e5dA:
undetectable		 2avdB-3e5dA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		4 / 5 LEU A  87
LEU A  91
LEU A 115
MET A  16
 None
 0.94A 2oaxF-3e5dA:
undetectable		 2oaxF-3e5dA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		3 / 3 LEU A 115
PHE A  19
ILE A 122
 None
 0.77A 5dzk1-3e5dA:
undetectable
5dzkF-3e5dA:
undetectable
5dzkM-3e5dA:
undetectable		 5dzk1-3e5dA:
14.29
5dzkF-3e5dA:
21.03
5dzkM-3e5dA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 12 ILE A  74
ILE A  76
THR A  88
ILE A  98
ALA A  99
 None
 1.09A 5vceA-3e5dA:
undetectable		 5vceA-3e5dA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 11 LEU A  87
THR A  88
PHE A  24
ILE A  76
ILE A 122
 None
 1.05A 6ebzA-3e5dA:
undetectable		 6ebzA-3e5dA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 11 LEU A  87
THR A  88
PHE A  24
ILE A  76
ILE A 122
 None
 1.03A 6ebzB-3e5dA:
undetectable		 6ebzB-3e5dA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 11 LEU A  87
THR A  88
PHE A  24
ILE A  76
ILE A 122
 None
 1.04A 6ebzC-3e5dA:
undetectable		 6ebzC-3e5dA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3e5d PUTATIVE GLYOXALASE
I
(Listeria
monocytogenes) 		5 / 11 LEU A  87
THR A  88
PHE A  24
ILE A  76
ILE A 122
 None
 1.03A 6ebzD-3e5dA:
undetectable		 6ebzD-3e5dA:
17.36