SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		6 / 12 PHE A 101
GLY A 102
GLY A 107
MET A 126
SER A 132
LEU A 133
 None
 0.86A 1v2xA-3e5yA:
16.2		 1v2xA-3e5yA:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A   6
LEU A 135
GLY A  16
ASN A  17
ALA A  23
 None
 1.19A 2bm9B-3e5yA:
3.1		 2bm9B-3e5yA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 12 ASN A  14
GLY A 102
GLY A 107
MET A 126
ASN A 134
 None
 0.69A 3nk7A-3e5yA:
15.9		 3nk7A-3e5yA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 12 ASN A  14
GLY A 102
MET A 126
SER A 132
ASN A 134
 None
 0.92A 3nk7A-3e5yA:
15.9		 3nk7A-3e5yA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		6 / 12 ASN A  14
PHE A 101
GLY A 102
GLY A 107
MET A 126
LEU A 133
 None
 0.68A 3nk7B-3e5yA:
15.9		 3nk7B-3e5yA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		6 / 12 ASN A  14
PHE A 101
GLY A 102
MET A 126
SER A 132
LEU A 133
 None
 0.86A 3nk7B-3e5yA:
15.9		 3nk7B-3e5yA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		4 / 5 LEU A  35
LEU A  39
MET A  57
THR A  15
 None
 1.31A 4do3A-3e5yA:
undetectable		 4do3A-3e5yA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 12 PHE A 101
LEU A 135
VAL A   4
LEU A   6
ILE A  19
 None
 1.08A 4g1bA-3e5yA:
undetectable		 4g1bA-3e5yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 11 ILE A  19
LEU A  49
ALA A  47
HIS A  30
LEU A   6
 None
 1.12A 4nqaA-3e5yA:
undetectable		 4nqaA-3e5yA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A 102
GLY A 107
SER A 132
LEU A 133
LEU A 135
 None
 0.79A 5l0zA-3e5yA:
17.9		 5l0zA-3e5yA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		5 / 10 GLY A 102
GLY A 107
SER A 132
LEU A 133
LEU A 135
 None
 0.59A 5l0zB-3e5yA:
13.4		 5l0zB-3e5yA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3e5y TRMH FAMILY RNA
METHYLTRANSFERASE
(Burkholderia
pseudomallei) 		4 / 8 ASN A  14
PRO A  13
ILE A  11
GLU A 104
 None
 1.04A 6hzpA-3e5yA:
undetectable		 6hzpA-3e5yA:
15.58