SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 6 LEU A 413
ARG A 365
TYR A 307
VAL A 246
 None
 1.12A 1db1A-3e60A:
undetectable		 1db1A-3e60A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 SER A 165
VAL A 166
GLY A 196
GLY A 173
 None
 0.79A 1f5lA-3e60A:
undetectable		 1f5lA-3e60A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 10 LEU A  91
VAL A 109
VAL A 191
GLY A 108
TYR A 157
 None
 1.38A 1fk9A-3e60A:
undetectable		 1fk9A-3e60A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A 173
VAL A 166
ALA A 355
GLY A 114
HIS A 347
 None
 1.17A 1kiaB-3e60A:
undetectable		 1kiaB-3e60A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 10 LEU A  91
VAL A 109
VAL A 191
GLY A 108
TYR A 157
 None
 1.36A 1lw0A-3e60A:
undetectable		 1lw0A-3e60A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 9 LEU A  91
VAL A 109
VAL A 191
GLY A 108
TYR A 157
 None
 1.31A 1lwfA-3e60A:
undetectable		 1lwfA-3e60A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A 173
SER A 113
THR A 168
ALA A 357
ILE A 177
 None
 1.11A 1nt2A-3e60A:
undetectable		 1nt2A-3e60A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 LEU A 413
ILE A 265
ALA A 357
ILE A 245
 None
 0.98A 1oniB-3e60A:
1.8
1oniC-3e60A:
undetectable		 1oniB-3e60A:
17.46
1oniC-3e60A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 6 LEU A  15
GLU A 224
ALA A  50
VAL A 238
 None
 1.19A 1sn5A-3e60A:
undetectable		 1sn5A-3e60A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 MET A 239
ALA A  49
ILE A 201
PHE A 209
 None
 0.93A 1upfB-3e60A:
undetectable		 1upfB-3e60A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A   8
ARG A 257
ASP A  93
ALA A  90
ALA A  87
 None
 1.05A 2br4A-3e60A:
undetectable		 2br4A-3e60A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 8 GLY A 353
GLY A 196
THR A 197
ALA A 243
ALA A 244
 None
 1.40A 2ej3C-3e60A:
undetectable		 2ej3C-3e60A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		6 / 12 GLY A 173
GLY A 350
THR A 168
ALA A 244
ALA A 357
ALA A 176
 None
 1.46A 2gluB-3e60A:
undetectable		 2gluB-3e60A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 ASP A 179
GLY A 267
ILE A 266
ALA A 357
ILE A 177
 None
 1.06A 2idwA-3e60A:
undetectable		 2idwA-3e60A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ARG A 365
ILE A   6
ILE A 177
ALA A 354
GLU A  20
 None
 0.97A 2j0dA-3e60A:
undetectable		 2j0dA-3e60A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 10 LEU A 110
GLY A 108
GLY A 195
LEU A 248
ALA A 180
 None
 0.98A 2v3kA-3e60A:
undetectable		 2v3kA-3e60A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 ALA A 287
GLY A 405
SER A 412
ALA A 411
 None
 0.79A 2vh3B-3e60A:
0.2		 2vh3B-3e60A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A 208
SER A 210
ALA A 207
SER A 199
PRO A 200
 None
 1.36A 2vmyB-3e60A:
undetectable		 2vmyB-3e60A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 SER A 113
ALA A 243
SER A 199
THR A 197
 None
 1.04A 3cfqA-3e60A:
undetectable
3cfqB-3e60A:
undetectable		 3cfqA-3e60A:
14.15
3cfqB-3e60A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 4 PRO A 280
TYR A 275
GLY A 408
THR A 409
 None
 1.26A 3ib0A-3e60A:
undetectable		 3ib0A-3e60A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A 173
GLY A 353
ALA A 357
ALA A 411
ALA A 194
 None
 0.98A 3jb2A-3e60A:
undetectable		 3jb2A-3e60A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		3 / 3 SER A 340
GLY A 312
SER A 227
 None
 0.63A 3loqA-3e60A:
undetectable		 3loqA-3e60A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 VAL A  12
ILE A 111
ALA A  85
ALA A  78
ALA A 149
 None
 1.02A 3mdtB-3e60A:
undetectable		 3mdtB-3e60A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		6 / 12 ALA A 244
ALA A  83
ALA A  86
ALA A 174
GLY A 173
ALA A 351
 None
 1.40A 3mg0Y-3e60A:
undetectable
3mg0Z-3e60A:
undetectable		 3mg0Y-3e60A:
19.91
3mg0Z-3e60A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ARG A  25
GLY A  17
ALA A  16
SER A  13
LEU A  15
 None
 1.12A 3n8xA-3e60A:
undetectable		 3n8xA-3e60A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 LEU A 348
ALA A 310
GLY A  32
PRO A  14
 None
 0.91A 3ny4A-3e60A:
undetectable		 3ny4A-3e60A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 PRO A 370
LEU A  11
THR A 341
ILE A 345
 None
 0.94A 3p50A-3e60A:
undetectable		 3p50A-3e60A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 PRO A 370
LEU A  11
THR A 341
ILE A 345
 None
 0.94A 3p50B-3e60A:
undetectable		 3p50B-3e60A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 PRO A 370
LEU A  11
THR A 341
ILE A 345
 None
 0.94A 3p50C-3e60A:
undetectable		 3p50C-3e60A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 PRO A 370
LEU A  11
THR A 341
ILE A 345
 None
 0.95A 3p50D-3e60A:
undetectable		 3p50D-3e60A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 PRO A 370
LEU A  11
THR A 341
ILE A 345
 None
 0.96A 3p50E-3e60A:
undetectable		 3p50E-3e60A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 10 LEU A  91
VAL A 109
VAL A 191
GLY A 108
TYR A 157
 None
 1.39A 3qipA-3e60A:
undetectable		 3qipA-3e60A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 6 ALA A 194
ILE A 177
LEU A 248
ALA A  90
 None
 0.90A 3r9sA-3e60A:
undetectable		 3r9sA-3e60A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 PHE A 237
ALA A 352
PHE A 209
PHE A 406
 None
 1.01A 3t3sF-3e60A:
undetectable		 3t3sF-3e60A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 HIS A 253
VAL A 191
VAL A 247
ASP A 103
 None
 1.00A 3uy4A-3e60A:
undetectable		 3uy4A-3e60A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ARG A 213
SER A 210
SER A  45
HIS A 347
LEU A 349
 None
 1.30A 3vt7A-3e60A:
undetectable		 3vt7A-3e60A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 5 ASP A 273
GLU A 285
GLY A 284
TYR A 275
 None
 1.30A 3w9tD-3e60A:
undetectable		 3w9tD-3e60A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 LEU A 305
SER A 283
PHE A 404
ASN A 410
ASN A 402
 None
 1.49A 4amjB-3e60A:
undetectable		 4amjB-3e60A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 6 ALA A 357
LEU A 413
VAL A 414
GLU A 264
 None
 0.99A 4g24A-3e60A:
undetectable		 4g24A-3e60A:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		10 / 12 GLY A 114
ALA A 169
CYH A 170
GLU A 198
PHE A 209
HIS A 311
THR A 313
HIS A 347
LEU A 349
GLY A 405
 None
 0.69A 4ls7A-3e60A:
67.0		 4ls7A-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		7 / 12 GLY A 114
ALA A 169
GLU A 198
SER A 205
PHE A 209
GLY A 405
PHE A 406
 None
 1.00A 4ls7A-3e60A:
67.0		 4ls7A-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		8 / 12 GLY A 114
ALA A 169
GLU A 198
SER A 205
PHE A 209
HIS A 347
LEU A 349
GLY A 405
 None
 0.75A 4ls7A-3e60A:
67.0		 4ls7A-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		8 / 12 ALA A 169
CYH A 170
PHE A 209
HIS A 311
THR A 313
HIS A 347
LEU A 349
GLY A 405
 None
 0.70A 4ls7A-3e60A:
67.0
4ls7B-3e60A:
66.7		 4ls7A-3e60A:
49.08
4ls7B-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ALA A 169
SER A 205
PHE A 209
GLY A 405
PHE A 406
 None
 1.00A 4ls7A-3e60A:
67.0
4ls7B-3e60A:
66.7		 4ls7A-3e60A:
49.08
4ls7B-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		6 / 12 ALA A 169
SER A 205
PHE A 209
HIS A 347
LEU A 349
GLY A 405
 None
 0.78A 4ls7A-3e60A:
67.0
4ls7B-3e60A:
66.7		 4ls7A-3e60A:
49.08
4ls7B-3e60A:
49.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ILE A 115
ALA A 169
CYH A 170
HIS A 311
GLY A 405
 None
 0.70A 4ls7A-3e60A:
67.0
4ls7B-3e60A:
66.7		 4ls7A-3e60A:
49.08
4ls7B-3e60A:
49.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 ASP A 231
VAL A 319
ALA A 317
SER A 314
GLY A 312
 None
 1.30A 4mmaA-3e60A:
undetectable		 4mmaA-3e60A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ALA A 169
GLY A 312
SER A 403
SER A 171
GLY A 405
 None
None
K  A 601 ( 4.5A)
None
None
 1.19A 4mmdB-3e60A:
undetectable		 4mmdB-3e60A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 LEU A 193
ALA A  86
ILE A 177
ALA A 354
ILE A   6
 None
 0.95A 4o2bD-3e60A:
undetectable		 4o2bD-3e60A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 ALA A 310
ILE A 380
GLU A 321
THR A 315
 None
 0.84A 4r20A-3e60A:
undetectable		 4r20A-3e60A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		3 / 3 GLU A 264
ALA A 263
PHE A 418
 None
 0.65A 4v1fA-3e60A:
undetectable		 4v1fA-3e60A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		3 / 3 GLU A 264
ALA A 263
PHE A 418
 None
 0.63A 4v1fC-3e60A:
undetectable		 4v1fC-3e60A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 GLY A 267
ALA A 263
ILE A   6
LEU A 251
MET A   1
 None
 0.90A 4xumB-3e60A:
undetectable		 4xumB-3e60A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		6 / 9 LEU A 413
ALA A 174
ALA A 176
ALA A 194
LEU A 248
ALA A 357
 None
 1.27A 4z91F-3e60A:
undetectable
4z91G-3e60A:
undetectable
4z91H-3e60A:
undetectable
4z91I-3e60A:
undetectable
4z91J-3e60A:
undetectable		 4z91F-3e60A:
22.30
4z91G-3e60A:
22.30
4z91H-3e60A:
22.30
4z91I-3e60A:
22.30
4z91J-3e60A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 THR A 168
SER A 403
ALA A 294
GLU A 356
GLY A 195
 None
K  A 601 ( 4.5A)
None
K  A 601 (-3.4A)
None
 1.09A 4zjoD-3e60A:
undetectable		 4zjoD-3e60A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 7 ALA A 149
ASP A 179
GLY A 173
THR A 409
 None
 0.98A 5bs8A-3e60A:
undetectable
5bs8B-3e60A:
undetectable
5bs8C-3e60A:
undetectable		 5bs8A-3e60A:
24.35
5bs8B-3e60A:
24.42
5bs8C-3e60A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.98A 5eevL-3e60A:
undetectable
5eevV-3e60A:
undetectable		 5eevL-3e60A:
12.18
5eevV-3e60A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.98A 5eewL-3e60A:
undetectable
5eewV-3e60A:
undetectable		 5eewL-3e60A:
12.18
5eewV-3e60A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.98A 5ef3L-3e60A:
undetectable
5ef3V-3e60A:
undetectable		 5ef3L-3e60A:
12.18
5ef3V-3e60A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 11 LEU A  91
VAL A 109
VAL A 191
GLY A 108
TYR A 157
 None
 1.39A 5hbmA-3e60A:
undetectable		 5hbmA-3e60A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 5 TYR A 268
SER A 412
ALA A 411
THR A 409
 None
 1.29A 5n0tA-3e60A:
undetectable		 5n0tA-3e60A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 5 TYR A 268
SER A 412
ALA A 411
THR A 409
 None
 1.37A 5n0wB-3e60A:
undetectable		 5n0wB-3e60A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 5 GLU A 420
LYS A 255
GLU A 264
PHE A 418
 None
 1.41A 5onlA-3e60A:
undetectable		 5onlA-3e60A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 ALA A 149
ARG A 144
GLY A 116
GLY A 114
MET A 239
 None
 1.21A 5ul4A-3e60A:
undetectable		 5ul4A-3e60A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		3 / 3 TYR A  62
ALA A  78
TYR A  82
 None
 0.86A 5uunB-3e60A:
undetectable		 5uunB-3e60A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 8 ALA A 244
SER A 113
THR A 172
GLY A 242
 None
 1.00A 5v0vA-3e60A:
undetectable		 5v0vA-3e60A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 GLY A 408
PRO A 280
ALA A 279
ASP A 273
THR A 409
 None
 1.16A 5x6yC-3e60A:
undetectable		 5x6yC-3e60A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		5 / 12 VAL A  54
THR A  61
GLY A  57
VAL A  81
TYR A  82
 None
 1.13A 6drzA-3e60A:
undetectable		 6drzA-3e60A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3e60 3-OXOACYL-[ACYL-CARR
IER-PROTEIN ]
SYNTHASE II
(Bartonella
henselae) 		4 / 5 GLU A 420
LYS A 255
GLU A 264
PHE A 418
 None
 1.43A 6hrjA-3e60A:
undetectable		 6hrjA-3e60A:
22.33