SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 PHE A 111
GLY A 118
LEU A 294
VAL A  81
 None
 0.98A 1gsfA-3e61A:
undetectable		 1gsfA-3e61A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 PHE A 111
GLY A 118
LEU A 294
VAL A  81
 None
 0.99A 1gsfB-3e61A:
undetectable		 1gsfB-3e61A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 PHE A 111
GLY A 118
LEU A 294
VAL A  81
 None
 0.98A 1gsfC-3e61A:
undetectable		 1gsfC-3e61A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 PHE A 111
GLY A 118
LEU A 294
VAL A  81
 None
 0.98A 1gsfD-3e61A:
undetectable		 1gsfD-3e61A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 LEU A  64
GLY A  95
PHE A  74
ASN A 125
 None
None
GOL  A   1 ( 4.5A)
None
 1.33A 3uq6B-3e61A:
undetectable		 3uq6B-3e61A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		5 / 11 ILE A 241
ASP A 237
ILE A 276
GLY A 262
VAL A 254
 None
 1.10A 4ac9B-3e61A:
3.9
4ac9C-3e61A:
3.7		 4ac9B-3e61A:
19.67
4ac9C-3e61A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 ALA A 187
HIS A 157
GLN A 281
TYR A 263
 GOL  A   1 ( 4.1A)
GOL  A   1 ( 4.7A)
GOL  A   1 (-3.3A)
None
 1.17A 4gboA-3e61A:
undetectable		 4gboA-3e61A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 ALA A 187
HIS A 157
GLN A 281
TYR A 263
 GOL  A   1 ( 4.1A)
GOL  A   1 ( 4.7A)
GOL  A   1 (-3.3A)
None
 1.13A 4gboB-3e61A:
undetectable		 4gboB-3e61A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 6 PHE A 158
LYS A 156
GLY A 161
ALA A 165
 None
 1.30A 4yshB-3e61A:
undetectable		 4yshB-3e61A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		5 / 12 LEU A  61
GLY A 118
LYS A 138
LEU A  65
LEU A 108
 None
 1.23A 5nwvA-3e61A:
undetectable		 5nwvA-3e61A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 ALA A 187
HIS A 157
GLN A 281
TYR A 263
 GOL  A   1 ( 4.1A)
GOL  A   1 ( 4.7A)
GOL  A   1 (-3.3A)
None
 1.19A 5uizA-3e61A:
undetectable		 5uizA-3e61A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 ASN A  99
ASP A  68
ASN A  71
ASP A 264
 None
None
GOL  A   1 (-3.4A)
GOL  A   1 (-2.6A)
 1.45A 5vooA-3e61A:
2.9		 5vooA-3e61A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 5 ASN A  99
ASP A  68
ASN A  71
ASP A 264
 None
None
GOL  A   1 (-3.4A)
GOL  A   1 (-2.6A)
 1.45A 5vooC-3e61A:
2.6		 5vooC-3e61A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 6 GLY A 161
LEU A 163
PHE A  73
PHE A  74
 None
None
GOL  A   1 (-4.1A)
GOL  A   1 ( 4.5A)
 0.98A 6h7lA-3e61A:
undetectable		 6h7lA-3e61A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 6 GLY A 161
LEU A 163
PHE A  73
PHE A  74
 None
None
GOL  A   1 (-4.1A)
GOL  A   1 ( 4.5A)
 0.99A 6h7lB-3e61A:
undetectable		 6h7lB-3e61A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 ASP A 186
ILE A 185
ASN A  71
TYR A 263
 None
None
GOL  A   1 (-3.4A)
None
 1.15A 6hisA-3e61A:
undetectable
6hisB-3e61A:
undetectable		 6hisA-3e61A:
15.51
6hisB-3e61A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 ASP A 186
ILE A 185
ASN A  71
TYR A 263
 None
None
GOL  A   1 (-3.4A)
None
 1.16A 6hisB-3e61A:
undetectable
6hisC-3e61A:
undetectable		 6hisB-3e61A:
15.51
6hisC-3e61A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 ASP A 186
ILE A 185
ASN A  71
TYR A 263
 None
None
GOL  A   1 (-3.4A)
None
 1.15A 6hisC-3e61A:
undetectable
6hisD-3e61A:
undetectable		 6hisC-3e61A:
15.51
6hisD-3e61A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 ASP A 186
ILE A 185
ASN A  71
TYR A 263
 None
None
GOL  A   1 (-3.4A)
None
 1.15A 6hisD-3e61A:
undetectable
6hisE-3e61A:
undetectable		 6hisD-3e61A:
15.51
6hisE-3e61A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON
(Staphylococcus
saprophyticus) 		4 / 8 ASN A  71
TYR A 263
ASP A 186
ILE A 185
 GOL  A   1 (-3.4A)
None
None
None
 1.15A 6hisA-3e61A:
undetectable
6hisE-3e61A:
undetectable		 6hisA-3e61A:
15.51
6hisE-3e61A:
15.51