SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 3e6c CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 9 THR C 104
LEU C  56
ALA C  96
TYR C  95
GLU C  72
 None
 1.46A 2azqA-3e6cC:
undetectable		 2azqA-3e6cC:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3e6c CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Desulfitobacteri
um
hafniense) 		4 / 7 LEU C  83
SER C  82
ARG C  26
ILE C  22
 None
 0.92A 3ln1B-3e6cC:
undetectable		 3ln1B-3e6cC:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 3e6c CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Desulfitobacteri
um
hafniense) 		4 / 7 ASN C 129
TYR C 130
LEU C  83
PHE C 116
 None
3C4  C 604 (-4.7A)
None
None
 1.39A 4awuA-3e6cC:
undetectable		 4awuA-3e6cC:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 3e6c CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 ILE C  22
ILE C  84
LEU C  87
LEU C 112
ILE C 126
 None
3C4  C 604 (-4.4A)
None
None
None
 1.05A 4m2xE-3e6cC:
undetectable		 4m2xE-3e6cC:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3e6c CYCLIC
NUCLEOTIDE-BINDING
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 VAL C  43
ALA C  42
GLY C  59
GLY C  40
THR C 104
 None
 1.13A 4mm8A-3e6cC:
undetectable		 4mm8A-3e6cC:
19.85