SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 8 ASP L 223
ASP L 225
TRP L 230
TYR L 232
 None
 0.29A 1ceaA-3e6pL:
undetectable
1ceaB-3e6pL:
undetectable		 1ceaA-3e6pL:
22.70
1ceaB-3e6pL:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP L 223
ASP L 225
TRP L 230
TYR L 232
 None
 0.33A 1ceaB-3e6pL:
undetectable		 1ceaB-3e6pL:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP L 223
ASP L 225
TRP L 230
TYR L 232
 None
 0.46A 1cebA-3e6pL:
10.5		 1cebA-3e6pL:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 7 ASP L 223
ASP L 225
TRP L 230
TYR L 232
 None
 0.33A 1cebB-3e6pL:
10.5		 1cebB-3e6pL:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 8 GLN L 176
GLN L 206
TYR L 232
TRP L 230
 None
 1.39A 2vxaA-3e6pL:
undetectable
2vxaK-3e6pL:
undetectable
2vxaL-3e6pL:
undetectable		 2vxaA-3e6pL:
16.88
2vxaK-3e6pL:
16.88
2vxaL-3e6pL:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3e6p PROTHROMBIN
(Homo
sapiens) 		4 / 8 VAL L 212
ASP L 173
GLY L 224
TYR L 247
 None
 1.04A 3af0A-3e6pL:
undetectable		 3af0A-3e6pL:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 3e6p PROTHROMBIN
(Homo
sapiens) 		5 / 9 ASP L 223
ASP L 225
TRP L 230
TYR L 232
PHE L 240
 None
 0.53A 4bvvA-3e6pL:
10.8		 4bvvA-3e6pL:
25.53