SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 8 PRO A   2
LEU A  80
GLY A  81
LEU A  29
 None
 0.83A 1ya4A-3e6qA:
undetectable		 1ya4A-3e6qA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 PRO A   2
LEU A  80
GLY A  81
LEU A  29
 None
 0.84A 1ya4B-3e6qA:
undetectable		 1ya4B-3e6qA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 10 THR A  16
GLY A  19
LEU A  21
LEU A  22
ILE A   6
 None
 1.31A 3kvrB-3e6qA:
undetectable		 3kvrB-3e6qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A  16
GLY A  19
LEU A  21
LEU A  22
ILE A   6
 None
 1.31A 3nbqA-3e6qA:
undetectable		 3nbqA-3e6qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  21
ALA A   8
GLY A  95
THR A  16
 None
ACT  A 337 (-3.4A)
None
None
 0.70A 3spkB-3e6qA:
undetectable		 3spkB-3e6qA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A   4
ALA A  64
LEU A  66
VAL A 102
 None
 0.72A 4iizB-3e6qA:
undetectable		 4iizB-3e6qA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE
(Pseudomonas
aeruginosa) 		3 / 3 PHE A  35
ARG A  72
ALA A  79
 None
 0.70A 6ecfB-3e6qA:
undetectable		 6ecfB-3e6qA:
21.18