SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.10A 1dyiB-3e79A:
undetectable		 1dyiB-3e79A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 ASP A 280
LEU A 277
HIS A 303
 None
 0.52A 1qknA-3e79A:
undetectable		 1qknA-3e79A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 7 MET A 332
ALA A 305
PHE A 324
GLU A 308
 None
None
None
TPP  A 551 ( 4.9A)
 1.25A 1t9wA-3e79A:
undetectable		 1t9wA-3e79A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 PHE A  72
TYR A 384
TYR A 381
 None
 0.75A 1x70B-3e79A:
undetectable		 1x70B-3e79A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 PHE A 122
TYR A 384
TYR A 381
 None
 0.76A 1x70B-3e79A:
undetectable		 1x70B-3e79A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 ASP A 280
LEU A 277
ILE A 304
SER A 307
PHE A 306
 None
 1.38A 1xoqA-3e79A:
undetectable		 1xoqA-3e79A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 ASP A 280
LEU A 277
ILE A 304
SER A 307
PHE A 306
 None
 1.39A 1xoqB-3e79A:
undetectable		 1xoqB-3e79A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 8 TYR A 162
ILE A 336
GLY A 165
PHE A 243
 None
 0.81A 2vctA-3e79A:
undetectable		 2vctA-3e79A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 8 TYR A 162
ILE A 336
GLY A 165
PHE A 243
 None
 0.87A 2vctB-3e79A:
undetectable		 2vctB-3e79A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 8 TYR A 162
ILE A 336
GLY A 165
PHE A 243
 None
 0.90A 2vctC-3e79A:
undetectable		 2vctC-3e79A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 7 TYR A 162
ILE A 336
GLY A 165
PHE A 243
 None
 0.84A 2vctD-3e79A:
undetectable		 2vctD-3e79A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 7 ILE A 181
SER A 311
TYR A 202
TYR A 187
 None
 1.38A 2xz5D-3e79A:
undetectable
2xz5E-3e79A:
undetectable		 2xz5D-3e79A:
21.43
2xz5E-3e79A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 TYR A 381
GLU A 308
ASP A 294
 None
TPP  A 551 ( 4.9A)
None
 0.77A 3bxoA-3e79A:
undetectable		 3bxoA-3e79A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 TYR A 381
GLU A 308
ASP A 294
 None
TPP  A 551 ( 4.9A)
None
 0.82A 3bxoB-3e79A:
undetectable		 3bxoB-3e79A:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 10 TYR A 215
TRP A 314
TYR A 343
ASP A 344
GLY A 380
 TPP  A 551 (-3.7A)
TPP  A 551 (-3.7A)
TPP  A 551 (-4.2A)
TPP  A 551 (-3.3A)
TPP  A 551 (-3.5A)
 0.32A 3myuA-3e79A:
41.0		 3myuA-3e79A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MYU_B_VIBB500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 10 ASN A 200
TYR A 215
TYR A 343
ASP A 344
GLY A 380
 TPP  A 551 (-3.3A)
TPP  A 551 (-3.7A)
TPP  A 551 (-4.2A)
TPP  A 551 (-3.3A)
TPP  A 551 (-3.5A)
 0.79A 3myuB-3e79A:
40.8		 3myuB-3e79A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MYU_B_VIBB500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 10 TYR A 215
TRP A 314
TYR A 343
ASP A 344
GLY A 380
 TPP  A 551 (-3.7A)
TPP  A 551 (-3.7A)
TPP  A 551 (-4.2A)
TPP  A 551 (-3.3A)
TPP  A 551 (-3.5A)
 0.39A 3myuB-3e79A:
40.8		 3myuB-3e79A:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 GLY A  49
ASP A 105
ILE A 103
GLY A 123
ASN A 125
 None
 1.37A 3ps9A-3e79A:
undetectable		 3ps9A-3e79A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.09A 3ql0A-3e79A:
undetectable		 3ql0A-3e79A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 11 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.03A 4i1nA-3e79A:
undetectable		 4i1nA-3e79A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 8 ALA A 283
SER A 282
TYR A 288
ARG A 244
 None
 0.86A 4ijiF-3e79A:
undetectable		 4ijiF-3e79A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.09A 4pstA-3e79A:
undetectable		 4pstA-3e79A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.02A 4qlgA-3e79A:
undetectable		 4qlgA-3e79A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.02A 4qlgB-3e79A:
undetectable		 4qlgB-3e79A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 9 PHE A 122
LEU A 145
TYR A 384
PHE A  72
ASP A 373
 None
 1.46A 4qopA-3e79A:
undetectable		 4qopA-3e79A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 9 PHE A 122
LEU A 145
TYR A 384
PHE A  72
ASP A 373
 None
 1.46A 4qopB-3e79A:
undetectable		 4qopB-3e79A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.08A 4rgcA-3e79A:
undetectable		 4rgcA-3e79A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 9 PHE A 364
ILE A 360
GLY A 346
LEU A 109
LEU A 120
 None
 1.21A 4ze0A-3e79A:
undetectable		 4ze0A-3e79A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 6 SER A 127
ASP A 155
ARG A 216
GLY A 217
 None
 0.91A 5cdnR-3e79A:
undetectable
5cdnS-3e79A:
undetectable		 5cdnR-3e79A:
21.77
5cdnS-3e79A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		3 / 3 ASP A 373
ASN A 366
PHE A  80
 None
 0.77A 5dsgB-3e79A:
undetectable		 5dsgB-3e79A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		5 / 12 LEU A  73
PHE A  76
LYS A  77
TYR A 384
THR A 374
 None
 1.02A 5e8qA-3e79A:
undetectable		 5e8qA-3e79A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 6 LEU A 379
VAL A 361
PHE A  48
PHE A 348
 None
 1.05A 6h7lA-3e79A:
undetectable		 6h7lA-3e79A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3e79 HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
hyorhinis) 		4 / 6 LEU A 379
VAL A 361
PHE A  48
PHE A 348
 None
 1.04A 6h7lB-3e79A:
undetectable		 6h7lB-3e79A:
10.58