SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 ILE A  73
ALA A  70
LEU A  69
ARG A 121
VAL A  58
 None
 1.18A 1i9gA-3e7nA:
undetectable		 1i9gA-3e7nA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 6 LEU A  24
VAL A  26
ILE A 120
MET A  62
ILE A  15
 None
 1.41A 2piwA-3e7nA:
undetectable		 2piwA-3e7nA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 LEU A  85
LEU A  88
LEU A  91
GLN A  95
LEU A  69
 None
 1.46A 2w8yB-3e7nA:
undetectable		 2w8yB-3e7nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 PHE A  51
LEU A  80
GLY A  30
LEU A  31
SER A 122
 None
None
EDO  A 300 (-4.1A)
EDO  A 300 (-4.3A)
None
 1.26A 3tbgA-3e7nA:
undetectable		 3tbgA-3e7nA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 PHE A  51
LEU A  80
GLY A  30
LEU A  31
SER A 122
 None
None
EDO  A 300 (-4.1A)
EDO  A 300 (-4.3A)
None
 1.26A 3tbgC-3e7nA:
undetectable		 3tbgC-3e7nA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		4 / 8 VAL A  57
ARG A  60
VAL A  48
GLY A  47
 None
 0.95A 4mk4A-3e7nA:
undetectable		 4mk4A-3e7nA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 ILE A 132
PHE A 109
LYS A 110
LEU A  31
PRO A  32
 None
None
None
EDO  A 300 (-4.3A)
None
 1.02A 5eajB-3e7nA:
2.2		 5eajB-3e7nA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		5 / 12 MET A  62
ILE A  15
VAL A  64
ALA A  67
LEU A  69
 None
 1.35A 5igpA-3e7nA:
undetectable		 5igpA-3e7nA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3e7n D-RIBOSE
HIGH-AFFINITY
TRANSPORT SYSTEM
(Salmonella
enterica) 		4 / 4 GLN A 108
THR A 104
GLU A  72
LEU A  31
 None
None
None
EDO  A 300 (-4.3A)
 1.48A 5m66A-3e7nA:
undetectable		 5m66A-3e7nA:
14.32