SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 202
VAL A 197
TRP A 196
 None
 0.77A 1kqeA-3e7qA:
undetectable
1kqeE-3e7qA:
undetectable		 1kqeA-3e7qA:
5.52
1kqeE-3e7qA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 202
VAL A 197
TRP A 196
 None
 0.75A 1kqeB-3e7qA:
undetectable
1kqeD-3e7qA:
undetectable		 1kqeB-3e7qA:
5.52
1kqeD-3e7qA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 196
ALA A 202
VAL A 197
 None
 0.76A 1kqeB-3e7qA:
undetectable
1kqeD-3e7qA:
undetectable		 1kqeB-3e7qA:
5.52
1kqeD-3e7qA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 196
ALA A 202
VAL A 197
 None
 0.75A 1kqeA-3e7qA:
undetectable
1kqeE-3e7qA:
undetectable		 1kqeA-3e7qA:
5.52
1kqeE-3e7qA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 170
LEU A 173
LEU A 105
SER A 101
 None
 0.97A 3vhuA-3e7qA:
undetectable		 3vhuA-3e7qA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 8 VAL A  62
ASP A  59
SER A  36
GLY A  57
ALA A  65
 None
 1.43A 4m48A-3e7qA:
undetectable		 4m48A-3e7qA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  46
PHE A   7
GLY A  49
LEU A  61
LEU A  19
 None
 0.98A 5x23A-3e7qA:
undetectable		 5x23A-3e7qA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 3e7q TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 GLN A  33
GLY A 127
SER A 122
GLY A 121
 None
 0.70A 6ekzA-3e7qA:
undetectable		 6ekzA-3e7qA:
17.82