SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e81'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 111
VAL A 114
ILE A 116
VAL A 151
ILE A   7
 None
 1.27A 1gebA-3e81A:
undetectable		 1gebA-3e81A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 THR A   9
ILE A  52
GLY A  51
ILE A  40
 None
 0.82A 2y7wC-3e81A:
1.3		 2y7wC-3e81A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 118
GLY A 102
ALA A 108
LEU A 130
VAL A 151
 None
 1.12A 3dmhA-3e81A:
2.5		 3dmhA-3e81A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  45
HIS A  44
VAL A  50
 None
EDO  A 168 (-3.9A)
None
 0.90A 3elzB-3e81A:
undetectable		 3elzB-3e81A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A  64
ARG A 145
GLY A  39
GLU A 149
 None
 1.11A 3k9fA-3e81A:
undetectable
3k9fB-3e81A:
undetectable
3k9fC-3e81A:
undetectable		 3k9fA-3e81A:
17.07
3k9fB-3e81A:
17.07
3k9fC-3e81A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A  64
ARG A 145
GLY A  39
GLU A 149
 None
 1.11A 3k9fA-3e81A:
undetectable
3k9fB-3e81A:
undetectable
3k9fD-3e81A:
undetectable		 3k9fA-3e81A:
17.07
3k9fB-3e81A:
17.07
3k9fD-3e81A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A   8
VAL A  70
TYR A  72
LEU A  53
TYR A 100
 None
 1.50A 6bsiA-3e81A:
undetectable		 6bsiA-3e81A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 LEU A 130
GLY A 118
ILE A 101
THR A   9
ASP A 103
ILE A 127
 None
None
None
None
MG  A 165 (-2.6A)
None
 1.45A 6emuA-3e81A:
2.2		 6emuA-3e81A:
23.19