SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_B_MTXB301_1
(PTERIDINE REDUCTASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 11 SER A 130
PHE A 132
LEU A  34
TYR A 310
LEU A  20
 None
 1.48A 1e7wB-3e82A:
8.5		 1e7wB-3e82A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 12 SER A 130
PHE A 132
LEU A  34
TYR A 310
LEU A  20
 None
 1.36A 1p33C-3e82A:
5.4		 1p33C-3e82A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 10 ALA A 340
ALA A 341
GLN A 351
ASN A 209
ILE A 235
 None
 1.07A 2aclC-3e82A:
undetectable		 2aclC-3e82A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A  94
VAL A  61
VAL A  76
ILE A  64
 None
 0.97A 2hyyB-3e82A:
undetectable		 2hyyB-3e82A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A  78
ILE A  35
ARG A 315
ILE A  16
 None
 0.91A 2q8hA-3e82A:
undetectable		 2q8hA-3e82A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 340
ALA A 341
GLN A 351
ASN A 209
ILE A 235
 None
 0.83A 3e00A-3e82A:
undetectable		 3e00A-3e82A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 11 LEU A  91
ALA A  47
GLY A  24
ILE A  81
ILE A  21
 None
 1.15A 3ebzA-3e82A:
undetectable		 3ebzA-3e82A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A  94
VAL A  61
VAL A  76
ILE A  64
 None
 1.02A 3k5vA-3e82A:
undetectable		 3k5vA-3e82A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A  94
VAL A  61
VAL A  76
ILE A  64
 None
 0.96A 3k5vB-3e82A:
undetectable		 3k5vB-3e82A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A  81
VAL A  80
GLY A  22
SER A  83
ARG A  49
 None
 1.00A 3mb5A-3e82A:
6.5		 3mb5A-3e82A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 8 TYR A 141
LEU A 236
GLN A 195
PHE A 159
 None
 1.02A 3po7A-3e82A:
2.4		 3po7A-3e82A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 11 LEU A  91
ALA A  47
GLY A  24
ILE A  81
ILE A  21
 None
 1.19A 3s53B-3e82A:
undetectable		 3s53B-3e82A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		3 / 3 GLN A 195
ASP A 264
GLN A 266
 None
 0.92A 4aztA-3e82A:
3.6		 4aztA-3e82A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		5 / 12 ASP A 264
PHE A 163
PHE A 249
SER A 139
GLY A 143
 None
 1.36A 4mm4A-3e82A:
undetectable		 4mm4A-3e82A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 VAL A 147
VAL A 156
TYR A 291
ARG A 136
 None
 1.12A 4r7iA-3e82A:
undetectable		 4r7iA-3e82A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		3 / 3 ARG A 308
ASP A 306
TRP A 281
 None
 1.09A 4xdqA-3e82A:
undetectable		 4xdqA-3e82A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 LEU A 338
ALA A 223
ASN A 220
ILE A 210
 None
 1.18A 4y03B-3e82A:
undetectable		 4y03B-3e82A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 ASP A  77
LYS A 100
HIS A 101
ARG A 127
 None
 0.29A 5a06A-3e82A:
29.7		 5a06A-3e82A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 ASP A  77
LYS A 100
HIS A 101
ARG A 127
 None
 0.26A 5a06B-3e82A:
29.8		 5a06B-3e82A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 ASP A  77
LYS A 100
HIS A 101
ARG A 127
 None
 0.27A 5a06D-3e82A:
29.8		 5a06D-3e82A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 ASP A  77
LYS A 100
HIS A 101
ARG A 127
 None
 0.28A 5a06F-3e82A:
29.9		 5a06F-3e82A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 6 ARG A 262
GLY A 282
ASP A 284
ASP A 280
 None
 1.32A 5hp1A-3e82A:
undetectable		 5hp1A-3e82A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 5 PRO A  67
ALA A  70
ALA A  47
ILE A  64
 None
 0.79A 5jncD-3e82A:
undetectable		 5jncD-3e82A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 302
SER A 139
ASP A 280
 None
 0.77A 5kvaA-3e82A:
5.4		 5kvaA-3e82A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 302
SER A 139
ASP A 280
 None
 0.80A 5kvaB-3e82A:
undetectable		 5kvaB-3e82A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		4 / 8 GLN A 146
GLY A 143
GLN A 307
ASP A 264
 None
 0.99A 5vlmD-3e82A:
undetectable		 5vlmD-3e82A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3e82 PUTATIVE
OXIDOREDUCTASE
(Klebsiella
pneumoniae) 		3 / 3 ASP A 140
PHE A 163
ARG A 135
 None
 0.82A 5yw0A-3e82A:
undetectable		 5yw0A-3e82A:
23.58