SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_M_TRPM81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 11	GLY A 77 HIS A 80 HIS A 82 SER A 21 ALA A 107	None None UNL A 200 (-4.1A) UNL A 200 ( 4.9A) None	1.11A	1gtnM-3e8oA: undetectable 1gtnN-3e8oA: undetectable	1gtnM-3e8oA: 19.83 1gtnN-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_O_TRPO81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 10	GLY A 77 HIS A 80 HIS A 82 SER A 21 ALA A 107	None None UNL A 200 (-4.1A) UNL A 200 ( 4.9A) None	1.16A	1gtnO-3e8oA: undetectable 1gtnP-3e8oA: undetectable	1gtnO-3e8oA: 19.83 1gtnP-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUV_A_VK3A4558_1 (PROTEIN YGIN)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	4 / 7	TYR A 55 GLU A 71 HIS A 82 LEU A 83	UNL A 200 (-4.4A) UNL A 200 (-2.8A) UNL A 200 (-4.1A) None	0.68A	1tuvA-3e8oA: 13.1	1tuvA-3e8oA: 23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1100_1 (SERUM ALBUMIN)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	4 / 4	LEU A 95 ARG A 36 LEU A 39 ALA A 27	None	1.20A	3b9mA-3e8oA: 2.4	3b9mA-3e8oA: 10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_A_C2FA1100_1 (GLYCINE N-METHYLTRANSFERASE)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	3 / 3	LEU A 83 HIS A 80 MET A 79	None	0.79A	3thrD-3e8oA: undetectable	3thrD-3e8oA: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 12	SER A 21 ALA A 107 GLY A 77 HIS A 80 HIS A 82	UNL A 200 ( 4.9A) None None None UNL A 200 (-4.1A)	1.15A	5eeuI-3e8oA: undetectable 5eeuJ-3e8oA: undetectable	5eeuI-3e8oA: 19.83 5eeuJ-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 10	GLY A 77 HIS A 80 HIS A 82 SER A 21 ALA A 107	None None UNL A 200 (-4.1A) UNL A 200 ( 4.9A) None	1.17A	5eeuQ-3e8oA: undetectable 5eeuR-3e8oA: undetectable	5eeuQ-3e8oA: 19.83 5eeuR-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 12	SER A 21 ALA A 107 GLY A 77 HIS A 80 HIS A 82	UNL A 200 ( 4.9A) None None None UNL A 200 (-4.1A)	1.16A	5eevI-3e8oA: undetectable 5eevJ-3e8oA: undetectable	5eevI-3e8oA: 19.83 5eevJ-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 10	GLY A 77 HIS A 80 HIS A 82 SER A 21 ALA A 107	None None UNL A 200 (-4.1A) UNL A 200 ( 4.9A) None	1.18A	5eevQ-3e8oA: undetectable 5eevR-3e8oA: undetectable	5eevQ-3e8oA: 19.83 5eevR-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 12	SER A 21 ALA A 107 GLY A 77 HIS A 80 HIS A 82	UNL A 200 ( 4.9A) None None None UNL A 200 (-4.1A)	1.16A	5eewI-3e8oA: undetectable 5eewJ-3e8oA: undetectable	5eewI-3e8oA: 19.83 5eewJ-3e8oA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_R_TRPR101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3e8o	UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD (Deinococcus radiodurans)	5 / 10	GLY A 77 HIS A 80 HIS A 82 SER A 21 ALA A 107	None None UNL A 200 (-4.1A) UNL A 200 ( 4.9A) None	1.18A	5eewQ-3e8oA: undetectable 5eewR-3e8oA: undetectable	5eewQ-3e8oA: 19.83 5eewR-3e8oA: 19.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTN_M_TRPM81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"GLY A  77;HIS A  80;HIS A  82;SER A  21;ALA A 107","None;None;UNL A 200 (-4.1A);UNL A 200 ( 4.9A);None","1.11A","1gtnM-3e8oA:undetectable;1gtnN-3e8oA:undetectable","1gtnM-3e8oA:19.83;1gtnN-3e8oA:19.83"],["1GTN_O_TRPO81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"GLY A  77;HIS A  80;HIS A  82;SER A  21;ALA A 107","None;None;UNL A 200 (-4.1A);UNL A 200 ( 4.9A);None","1.16A","1gtnO-3e8oA:undetectable;1gtnP-3e8oA:undetectable","1gtnO-3e8oA:19.83;1gtnP-3e8oA:19.83"],["1TUV_A_VK3A4558_1","PROTEIN YGIN","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",4,"TYR A  55;GLU A  71;HIS A  82;LEU A  83","UNL A 200 (-4.4A);UNL A 200 (-2.8A);UNL A 200 (-4.1A);None","0.68A","1tuvA-3e8oA:13.1","1tuvA-3e8oA:23.97"],["3B9M_A_SALA1100_1","SERUM ALBUMIN","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",4,"LEU A  95;ARG A  36;LEU A  39;ALA A  27","None","1.20A","3b9mA-3e8oA:2.4","3b9mA-3e8oA:10.86"],["3THR_A_C2FA1100_1","GLYCINE N-METHYLTRANSFERASE","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",3,"LEU A  83;HIS A  80;MET A  79","None","0.79A","3thrD-3e8oA:undetectable","3thrD-3e8oA:16.04"],["5EEU_I_TRPI101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"SER A  21;ALA A 107;GLY A  77;HIS A  80;HIS A  82","UNL A 200 ( 4.9A);None;None;None;UNL A 200 (-4.1A)","1.15A","5eeuI-3e8oA:undetectable;5eeuJ-3e8oA:undetectable","5eeuI-3e8oA:19.83;5eeuJ-3e8oA:19.83"],["5EEU_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"GLY A  77;HIS A  80;HIS A  82;SER A  21;ALA A 107","None;None;UNL A 200 (-4.1A);UNL A 200 ( 4.9A);None","1.17A","5eeuQ-3e8oA:undetectable;5eeuR-3e8oA:undetectable","5eeuQ-3e8oA:19.83;5eeuR-3e8oA:19.83"],["5EEV_I_TRPI101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"SER A  21;ALA A 107;GLY A  77;HIS A  80;HIS A  82","UNL A 200 ( 4.9A);None;None;None;UNL A 200 (-4.1A)","1.16A","5eevI-3e8oA:undetectable;5eevJ-3e8oA:undetectable","5eevI-3e8oA:19.83;5eevJ-3e8oA:19.83"],["5EEV_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"GLY A  77;HIS A  80;HIS A  82;SER A  21;ALA A 107","None;None;UNL A 200 (-4.1A);UNL A 200 ( 4.9A);None","1.18A","5eevQ-3e8oA:undetectable;5eevR-3e8oA:undetectable","5eevQ-3e8oA:19.83;5eevR-3e8oA:19.83"],["5EEW_I_TRPI101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"SER A  21;ALA A 107;GLY A  77;HIS A  80;HIS A  82","UNL A 200 ( 4.9A);None;None;None;UNL A 200 (-4.1A)","1.16A","5eewI-3e8oA:undetectable;5eewJ-3e8oA:undetectable","5eewI-3e8oA:19.83;5eewJ-3e8oA:19.83"],["5EEW_R_TRPR101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3e8o","UNCHARACTERIZED PROTEIN WITH FERREDOXIN-LIKE FOLD","Deinococcus radiodurans",5,"GLY A  77;HIS A  80;HIS A  82;SER A  21;ALA A 107","None;None;UNL A 200 (-4.1A);UNL A 200 ( 4.9A);None","1.18A","5eewQ-3e8oA:undetectable;5eewR-3e8oA:undetectable","5eewQ-3e8oA:19.83;5eewR-3e8oA:19.83"]]