SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 LEU A  20
LEU A 108
LEU A 105
LEU A 101
LEU A  83
 None
 1.02A 3erdA-3e8pA:
undetectable		 3erdA-3e8pA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 LEU A  20
LEU A 108
LEU A 105
LEU A 101
LEU A  83
 None
 1.02A 3hm1A-3e8pA:
undetectable		 3hm1A-3e8pA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		3 / 3 THR A 129
LYS A  12
GLU A  50
 None
 0.88A 3ijdB-3e8pA:
undetectable		 3ijdB-3e8pA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 10 VAL A 163
GLY A 164
VAL A 141
ASN A 137
GLY A 136
 None
 1.19A 3km6A-3e8pA:
undetectable		 3km6A-3e8pA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 9 VAL A 163
GLY A 164
VAL A 141
ASN A 137
GLY A 136
 None
 1.22A 3kmoA-3e8pA:
undetectable		 3kmoA-3e8pA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 LEU A 108
GLY A 159
VAL A 115
ALA A  85
ILE A 133
 None
 0.94A 3ku1H-3e8pA:
undetectable		 3ku1H-3e8pA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 ARG A 104
ILE A  98
PHE A  86
THR A 107
ALA A  91
 None
 1.33A 3ua1A-3e8pA:
undetectable		 3ua1A-3e8pA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 TYR A 117
ALA A 155
PHE A 126
ILE A  53
VAL A  72
 None
 1.24A 4azwA-3e8pA:
undetectable		 4azwA-3e8pA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		3 / 3 ASP A  28
VAL A  80
ASN A  35
 None
 0.71A 4lmnA-3e8pA:
undetectable		 4lmnA-3e8pA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		3 / 3 ASP A  40
VAL A  80
ASN A  35
 None
 0.78A 4lmnA-3e8pA:
undetectable		 4lmnA-3e8pA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 LEU A 105
LEU A  83
ALA A  24
VAL A  26
ILE A  41
 None
 1.07A 4x1yD-3e8pA:
undetectable		 4x1yD-3e8pA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 VAL A  31
HIS A  34
LEU A  39
VAL A  51
GLY A  81
 None
 1.43A 5i8fA-3e8pA:
undetectable		 5i8fA-3e8pA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		3 / 3 THR A 127
HIS A 147
ASN A 148
 None
 1.00A 5n4tA-3e8pA:
undetectable		 5n4tA-3e8pA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		5 / 12 VAL A  80
LEU A  83
LEU A  20
VAL A  23
ALA A  24
 None
 0.70A 6ajiA-3e8pA:
undetectable		 6ajiA-3e8pA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A 126
ILE A  53
LEU A  37
ILE A  67
 None
 0.85A 6b5vA-3e8pA:
undetectable
6b5vC-3e8pA:
undetectable		 6b5vA-3e8pA:
17.68
6b5vC-3e8pA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A 126
ILE A  53
LEU A  37
ILE A  67
 None
 0.84A 6b5vA-3e8pA:
undetectable
6b5vB-3e8pA:
1.8		 6b5vA-3e8pA:
17.68
6b5vB-3e8pA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A 126
ILE A  53
LEU A  37
ILE A  67
 None
 0.85A 6b5vC-3e8pA:
undetectable
6b5vD-3e8pA:
undetectable		 6b5vC-3e8pA:
17.68
6b5vD-3e8pA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3e8p UNCHARACTERIZED
PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A 126
ILE A  53
LEU A  37
ILE A  67
 None
 0.85A 6b5vB-3e8pA:
undetectable
6b5vD-3e8pA:
undetectable		 6b5vB-3e8pA:
17.68
6b5vD-3e8pA:
17.68