SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e8t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		3 / 3 ASP A  43
ASP A  46
LYS A 200
 None
 1.08A 1lqtB-3e8tA:
undetectable		 1lqtB-3e8tA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		3 / 3 ASP A  43
ASP A  46
LYS A 200
 None
 1.07A 1lquB-3e8tA:
undetectable		 1lquB-3e8tA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		5 / 12 MET A 174
LEU A 163
GLY A 110
LEU A  54
PHE A  47
 None
 1.15A 1pj7A-3e8tA:
undetectable		 1pj7A-3e8tA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		5 / 12 ALA A  91
GLY A  65
LEU A 116
LEU A 118
LEU A  58
 UQ8  A 221 ( 4.7A)
None
None
UQ8  A 221 (-4.9A)
None
 0.98A 2nyuB-3e8tA:
undetectable		 2nyuB-3e8tA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		4 / 6 PHE A 189
PHE A  49
GLY A 101
GLY A 100
 None
 0.87A 2qr2A-3e8tA:
undetectable
2qr2B-3e8tA:
undetectable		 2qr2A-3e8tA:
25.97
2qr2B-3e8tA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		4 / 5 GLY A 101
GLY A 100
PHE A 189
PHE A  49
 None
 0.89A 2qr2A-3e8tA:
undetectable
2qr2B-3e8tA:
undetectable		 2qr2A-3e8tA:
25.97
2qr2B-3e8tA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		3 / 3 ASP A 134
HIS A 140
LYS A 133
 None
 0.93A 4qzuD-3e8tA:
undetectable		 4qzuD-3e8tA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		5 / 12 LEU A  51
LEU A 116
PHE A  49
PHE A  47
ALA A 196
 None
 1.30A 5ieoA-3e8tA:
3.0		 5ieoA-3e8tA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 3e8t TAKEOUT-LIKE PROTEIN
1
(Epiphyas
postvittana) 		3 / 3 LYS A  62
VAL A  41
ASP A  43
 None
 0.63A 6fgdA-3e8tA:
undetectable		 6fgdA-3e8tA:
18.96