SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3e8u FAB 106.3 HEAVY
CHAIN
(Mus
musculus) 		4 / 8 GLY H  33
HIS H  53
THR H  52
ILE H  34
 None
 0.76A 1c9sI-3e8uH:
undetectable
1c9sJ-3e8uH:
undetectable		 1c9sI-3e8uH:
14.95
1c9sJ-3e8uH:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3e8u FAB 106.3 HEAVY
CHAIN
(Mus
musculus) 		4 / 8 GLY H  33
HIS H  53
THR H  52
ILE H  34
 None
 0.75A 1c9sU-3e8uH:
undetectable
1c9sV-3e8uH:
undetectable		 1c9sU-3e8uH:
14.95
1c9sV-3e8uH:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3e8u FAB 106.3 HEAVY
CHAIN
(Mus
musculus) 		4 / 8 GLY H  33
HIS H  53
THR H  52
ILE H  34
 None
 0.77A 1utdI-3e8uH:
undetectable
1utdJ-3e8uH:
undetectable		 1utdI-3e8uH:
14.95
1utdJ-3e8uH:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3e8u FAB 106.3 HEAVY
CHAIN
(Mus
musculus) 		4 / 4 ILE H  82
LEU H  80
LYS H  19
ASN H  82
 None
 1.40A 4g19D-3e8uH:
undetectable		 4g19D-3e8uH:
23.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3e8u FAB 106.3 HEAVY
CHAIN
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 172
ASP H 175
 None
 0.46A 5mthA-3e8uH:
28.2		 5mthA-3e8uH:
69.82