SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		5 / 12 ILE A 164
GLY A 235
VAL A  13
ALA A 225
LEU A 255
 None
 1.07A 1kiaC-3e9aA:
undetectable		 1kiaC-3e9aA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		5 / 12 ILE A 164
GLY A 235
VAL A  13
ALA A 225
LEU A 255
 None
 1.07A 1nbhB-3e9aA:
undetectable		 1nbhB-3e9aA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		3 / 3 LYS A  60
GLY A 251
PRO A 252
 None
 0.99A 2hreB-3e9aA:
undetectable		 2hreB-3e9aA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		3 / 3 ASP A  46
TYR A  52
LYS A  91
 None
 1.22A 2othA-3e9aA:
undetectable		 2othA-3e9aA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 7 PRO A 195
PHE A  22
ILE A 197
PRO A  12
 None
 0.99A 2y7kA-3e9aA:
undetectable		 2y7kA-3e9aA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 6 ARG A 168
ASP A 199
LYS A 138
LYS A  55
 SO4  A 284 (-3.9A)
None
SO4  A 284 (-3.1A)
None
 1.44A 3jqzA-3e9aA:
0.0		 3jqzA-3e9aA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
SO4  A 284 ( 4.8A)
 1.34A 3lskB-3e9aA:
undetectable		 3lskB-3e9aA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
SO4  A 284 ( 4.8A)
 1.33A 3lskD-3e9aA:
undetectable		 3lskD-3e9aA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 5 ASP A 199
ASP A  59
ASN A  26
GLU A 239
 None
 1.04A 3vywD-3e9aA:
1.8		 3vywD-3e9aA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		3 / 3 LYS A   4
LYS A 188
SER A 191
 None
 1.22A 5odiA-3e9aA:
undetectable		 5odiA-3e9aA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		4 / 8 ILE A 233
LEU A 229
MET A 267
LEU A 270
 None
 1.08A 5u4sB-3e9aA:
undetectable		 5u4sB-3e9aA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		5 / 12 LEU A 114
PRO A 115
PHE A 155
THR A 131
ILE A 135
 None
SO4  A 284 (-4.2A)
None
None
None
 1.17A 6debB-3e9aA:
undetectable		 6debB-3e9aA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3e9a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Vibrio
cholerae) 		5 / 10 THR A  94
GLY A  73
GLY A  77
VAL A 105
GLU A  76
 None
 1.24A 6nqaK-3e9aA:
undetectable		 6nqaK-3e9aA:
23.11