SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 12 VAL A   9
ASN A  73
LEU A  70
GLY A  43
ALA A  42
 None
 1.07A 1r9oA-3e9dA:
undetectable		 1r9oA-3e9dA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 5 ILE A 244
SER A 182
ARG A  10
ASN A 245
 None
None
PO4  A 267 ( 2.9A)
None
 0.97A 1y0xX-3e9dA:
undetectable		 1y0xX-3e9dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 12 VAL A 242
PHE A 140
LEU A 136
ALA A 178
PHE A   4
 None
 1.20A 3apwB-3e9dA:
undetectable		 3apwB-3e9dA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 6 ILE A  68
MET A  81
ILE A  63
HIS A  11
 None
None
None
PO4  A 266 (-4.0A)
 1.14A 3eteA-3e9dA:
undetectable
3eteE-3e9dA:
undetectable		 3eteA-3e9dA:
19.68
3eteE-3e9dA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 5 ILE A  68
MET A  81
ILE A  63
HIS A  11
 None
None
None
PO4  A 266 (-4.0A)
 1.13A 3eteB-3e9dA:
undetectable
3eteC-3e9dA:
undetectable		 3eteB-3e9dA:
19.68
3eteC-3e9dA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 7 MET A  81
ILE A  63
HIS A  11
ILE A  68
 None
None
PO4  A 266 (-4.0A)
None
 1.13A 3eteD-3e9dA:
undetectable
3eteF-3e9dA:
undetectable		 3eteD-3e9dA:
19.68
3eteF-3e9dA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 8 ARG A 238
GLY A 170
ALA A 171
ASP A 168
THR A   3
 None
 1.17A 4eyrB-3e9dA:
undetectable		 4eyrB-3e9dA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 7 ILE A   8
SER A 182
PHE A 135
ASP A 197
 None
 1.39A 4iarA-3e9dA:
undetectable		 4iarA-3e9dA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 11 ARG A 238
GLY A 170
ALA A 171
ASP A 168
THR A   3
 None
 1.10A 4l1aA-3e9dA:
undetectable		 4l1aA-3e9dA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 8 GLY A  24
GLN A  23
SER A  57
HIS A 183
 None
PO4  A 266 (-4.6A)
None
PO4  A 266 (-3.8A)
 0.94A 4wryA-3e9dA:
undetectable		 4wryA-3e9dA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 12 MET A 180
PHE A 223
ILE A   8
ALA A 185
ILE A 187
 None
 1.39A 5mlmA-3e9dA:
undetectable		 5mlmA-3e9dA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3e9d ZGC:56074
(Danio
rerio) 		3 / 3 HIS A 102
ASN A 105
ALA A 109
 None
 0.40A 5n4tB-3e9dA:
undetectable		 5n4tB-3e9dA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3e9d ZGC:56074
(Danio
rerio) 		5 / 12 ALA A  62
LEU A  83
ILE A  82
ARG A 142
PHE A 135
 None
 1.39A 5vlmE-3e9dA:
undetectable		 5vlmE-3e9dA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 5 LEU A 139
LEU A 194
THR A   7
PRO A 161
 None
 0.99A 6ew0F-3e9dA:
undetectable		 6ew0F-3e9dA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3e9d ZGC:56074
(Danio
rerio) 		4 / 6 LEU A 139
LEU A 194
THR A   7
PRO A 161
 None
 0.99A 6ew0G-3e9dA:
undetectable		 6ew0G-3e9dA:
15.47