SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 213
VAL A 211
GLY A 124
ILE A 167
THR A 221
 None
 1.31A 1t7iB-3e9nA:
undetectable		 1t7iB-3e9nA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 213
VAL A 211
GLY A 124
ILE A 167
THR A 221
 None
 1.29A 1t7jB-3e9nA:
undetectable		 1t7jB-3e9nA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  42
ALA A  80
ALA A  31
VAL A  29
LEU A 119
 None
 1.23A 3b0wA-3e9nA:
undetectable		 3b0wA-3e9nA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  42
ALA A  80
ALA A  31
VAL A  29
LEU A 119
 None
 1.21A 3b0wB-3e9nA:
undetectable		 3b0wB-3e9nA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 12 VAL A  20
GLY A  16
GLY A  33
ALA A  41
ALA A  40
 None
 1.00A 3sufD-3e9nA:
undetectable		 3sufD-3e9nA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		5 / 10 GLN A 114
HIS A  79
VAL A  59
LEU A  32
THR A   9
 None
 1.35A 4coqA-3e9nA:
undetectable		 4coqA-3e9nA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3e9n PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
(Corynebacterium
glutamicum) 		4 / 7 ALA A  11
THR A  12
ILE A  45
VAL A  20
 None
 0.94A 6cduF-3e9nA:
undetectable
6cduJ-3e9nA:
undetectable		 6cduF-3e9nA:
18.77
6cduJ-3e9nA:
18.77