SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.17A 3t3qA-3e9pA:
undetectable		 3t3qA-3e9pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.22A 3t3qB-3e9pA:
undetectable		 3t3qB-3e9pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.20A 3t3qC-3e9pA:
undetectable		 3t3qC-3e9pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 10 PHE A2005
PHE A1844
THR A1959
ILE A1934
PHE A1851
 None
 1.21A 3t3qD-3e9pA:
undetectable		 3t3qD-3e9pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		3 / 3 PRO A1925
LEU A1924
HIS A1888
 None
 0.68A 4pevA-3e9pA:
2.3		 4pevA-3e9pA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		5 / 12 LEU A2015
LEU A2012
TRP A1995
LEU A1889
LEU A2039
 None
 1.09A 5mwyA-3e9pA:
undetectable		 5mwyA-3e9pA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 3e9p PRE-MRNA-SPLICING
FACTOR 8
(Saccharomyces
cerevisiae) 		4 / 8 THR A2009
TYR A1840
PHE A1844
PRO A1884
 None
 1.24A 5v4vA-3e9pA:
undetectable		 5v4vA-3e9pA:
21.23