SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3e9u NA/CA EXCHANGE
PROTEIN
(Drosophila
melanogaster) 		5 / 12 GLY A 606
LEU A 624
ILE A 622
HIS A 641
TRP A 592
 None
 1.18A 1kyvA-3e9uA:
undetectable
1kyvE-3e9uA:
undetectable		 1kyvA-3e9uA:
23.63
1kyvE-3e9uA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3e9u NA/CA EXCHANGE
PROTEIN
(Drosophila
melanogaster) 		5 / 12 HIS A 641
TRP A 592
GLY A 606
LEU A 624
ILE A 622
 None
 1.18A 1kyvB-3e9uA:
undetectable
1kyvC-3e9uA:
undetectable		 1kyvB-3e9uA:
23.63
1kyvC-3e9uA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3e9u NA/CA EXCHANGE
PROTEIN
(Drosophila
melanogaster) 		5 / 12 HIS A 641
TRP A 592
GLY A 606
LEU A 624
ILE A 622
 None
 1.17A 1kyvC-3e9uA:
undetectable
1kyvD-3e9uA:
undetectable		 1kyvC-3e9uA:
23.63
1kyvD-3e9uA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3e9u NA/CA EXCHANGE
PROTEIN
(Drosophila
melanogaster) 		5 / 12 HIS A 641
TRP A 592
GLY A 606
LEU A 624
ILE A 622
 None
 1.16A 1kyvD-3e9uA:
undetectable
1kyvE-3e9uA:
undetectable		 1kyvD-3e9uA:
23.63
1kyvE-3e9uA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3e9u NA/CA EXCHANGE
PROTEIN
(Drosophila
melanogaster) 		4 / 5 GLY A 582
SER A 552
ARG A 681
GLY A 551
 None
 1.06A 5kprA-3e9uA:
undetectable		 5kprA-3e9uA:
20.72