SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eaa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3eaa EVPC
(Edwardsiella
tarda) 		4 / 6 SER A  16
GLU A  86
TYR A   6
CYH A  88
 None
 1.29A 2x7hA-3eaaA:
undetectable		 2x7hA-3eaaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3eaa EVPC
(Edwardsiella
tarda) 		5 / 12 LEU A   9
LEU A  83
LEU A  57
ILE A 126
ILE A   7
 None
 1.05A 4a7aB-3eaaA:
undetectable		 4a7aB-3eaaA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3eaa EVPC
(Edwardsiella
tarda) 		5 / 12 VAL A  27
ASP A  64
PHE A  80
LEU A  83
VAL A  59
 None
 1.38A 4kyaH-3eaaA:
undetectable		 4kyaH-3eaaA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 3eaa EVPC
(Edwardsiella
tarda) 		3 / 3 ASP A  18
HIS A  21
LYS A  22
 None
 0.95A 4qzuD-3eaaA:
undetectable		 4qzuD-3eaaA:
25.00