SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3eab CHMP1B
SPASTIN
(Homo
sapiens) 		5 / 9 ASP G 186
SER G 189
PHE A 124
SER G 182
SER G 179
 None
 1.50A 6awpA-3eabG:
undetectable		 6awpA-3eabG:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3eab SPASTIN
CHMP1B
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG A 176
LYS A 180
ARG G 196
 None
 1.32A 6c06D-3eabA:
3.0		 6c06D-3eabA:
undetectable