SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eak'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3eak NBBCII10-FGLA
(Camelus
dromedarius) 		4 / 7 PHE A  40
ALA A  53
LEU A  37
ALA A 100
 None
 0.97A 2vcvA-3eakA:
undetectable		 2vcvA-3eakA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3eak NBBCII10-FGLA
(Camelus
dromedarius) 		4 / 6 PHE A  40
ALA A  53
LEU A  37
ALA A 100
 None
 0.97A 2vcvB-3eakA:
undetectable		 2vcvB-3eakA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 3eak NBBCII10-FGLA
(Camelus
dromedarius) 		6 / 12 VAL A   2
LEU A   4
ALA A  24
ARG A  75
ALA A 101
TYR A 117
 None
 0.76A 3qxtB-3eakA:
21.9		 3qxtB-3eakA:
67.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3eak NBBCII10-FGLA
(Camelus
dromedarius) 		4 / 7 ALA A  95
THR A  94
VAL A 124
GLU A  92
 None
 0.84A 5ecoD-3eakA:
undetectable		 5ecoD-3eakA:
13.45