SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 5 MET X 114
HIS X 287
ARG X 194
ILE X 217
 None
 1.32A 1osvB-3eatX:
0.0		 1osvB-3eatX:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.11A 1tlsA-3eatX:
undetectable		 1tlsA-3eatX:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.15A 1tlsB-3eatX:
undetectable		 1tlsB-3eatX:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.13A 1tsnA-3eatX:
undetectable		 1tsnA-3eatX:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 4 LEU X  27
SER X   6
LEU X  58
LEU X  56
 None
 1.14A 1yajA-3eatX:
undetectable		 1yajA-3eatX:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 5 LEU X 249
LEU X  58
LEU X  41
CYH X  74
 None
 1.05A 2ab2B-3eatX:
undetectable		 2ab2B-3eatX:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 7 PRO X  31
HIS X  37
GLY X  35
GLU X  40
 None
 0.91A 3tehB-3eatX:
undetectable		 3tehB-3eatX:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		6 / 12 LEU X  58
LEU X 249
ILE X 251
ASP X  76
GLY X  39
VAL X  38
 None
 1.18A 4an2A-3eatX:
undetectable		 4an2A-3eatX:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 LEU X  89
LEU X  91
ALA X  67
HIS X 276
ASP X 112
 None
 1.04A 4aqlA-3eatX:
undetectable		 4aqlA-3eatX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 8 PHE X  77
PHE X 122
ALA X 252
LEU X 249
 None
 0.87A 4ejgB-3eatX:
undetectable		 4ejgB-3eatX:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 11 HIS X 239
SER X 142
GLY X  26
PHE X  25
VAL X 250
 None
 1.26A 4fogC-3eatX:
undetectable		 4fogC-3eatX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.10A 4foxA-3eatX:
undetectable		 4foxA-3eatX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 11 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.10A 4foxC-3eatX:
undetectable		 4foxC-3eatX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.12A 4foxE-3eatX:
undetectable		 4foxE-3eatX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 HIS X 239
SER X 142
LEU X  15
GLY X  26
PHE X  25
 None
 1.11A 4foxG-3eatX:
undetectable		 4foxG-3eatX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 6 ALA X 252
ASN X 254
LEU X 257
ASP X 112
 None
 0.72A 4g24A-3eatX:
undetectable		 4g24A-3eatX:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 8 LEU X  55
VAL X 250
HIS X 239
LEU X 109
 None
 1.02A 4l1xA-3eatX:
undetectable		 4l1xA-3eatX:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		4 / 6 GLU X 280
GLN X  44
THR X 256
HIS X  54
 None
 1.23A 4pfjB-3eatX:
undetectable		 4pfjB-3eatX:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 10 ILE X 251
LEU X  58
PHE X  77
LEU X  49
LEU X  12
 None
 1.30A 5fhzC-3eatX:
undetectable		 5fhzC-3eatX:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3eat PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCB
(Pseudomonas
aeruginosa) 		5 / 12 GLU X 121
GLN X   8
ARG X  51
GLY X  48
LEU X  49
 None
 1.48A 5m50B-3eatX:
undetectable		 5m50B-3eatX:
21.02