SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 11 PRO A 295
HIS A 322
PHE A 325
ASP A 300
LEU A 297
 None
 1.36A 1c3sA-3eb0A:
undetectable		 1c3sA-3eb0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A 162
SER A 227
ILE A 167
ASN A 171
LEU A 183
 None
None
None
DRK  A 384 ( 4.6A)
None
 1.02A 1dlsA-3eb0A:
undetectable		 1dlsA-3eb0A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 LEU A  15
GLY A  16
VAL A  23
ALA A  36
LEU A 173
TYR A 119
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 1.39A 1muoA-3eb0A:
18.7		 1muoA-3eb0A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 LEU A  15
GLY A  16
VAL A  23
ALA A  36
TYR A 119
LEU A 173
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.99A 1muoA-3eb0A:
18.7		 1muoA-3eb0A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A 162
PHE A 186
SER A 227
ILE A 167
LEU A 183
 None
 1.12A 1rx3A-3eb0A:
undetectable		 1rx3A-3eb0A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 5 GLY A 155
PRO A 365
VAL A 368
ILE A 372
 None
 0.97A 2aoiA-3eb0A:
undetectable		 2aoiA-3eb0A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
GLY A  16
VAL A  23
ALA A  36
TYR A 119
ASN A 171
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.6A)
DRK  A 384 ( 4.7A)
 1.02A 2fumB-3eb0A:
25.4		 2fumB-3eb0A:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
VAL A  23
ALA A  36
MET A 117
TYR A 119
ASN A 171
ASP A 185
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.6A)
DRK  A 384 ( 4.7A)
 0.89A 2fumB-3eb0A:
25.4		 2fumB-3eb0A:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
GLY A  16
GLY A  18
VAL A  23
ALA A  36
MET A 117
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 ( 4.7A)
 0.88A 2fumD-3eb0A:
17.4		 2fumD-3eb0A:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
GLY A  16
VAL A  23
ALA A  36
MET A 117
LYS A 168
ASN A 171
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
None
DRK  A 384 ( 4.6A)
DRK  A 384 ( 4.7A)
 0.89A 2fumD-3eb0A:
17.4		 2fumD-3eb0A:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
VAL A  23
ALA A  36
MET A 117
THR A 123
LYS A 168
ASN A 171
ASP A 185
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 ( 4.5A)
None
DRK  A 384 ( 4.6A)
DRK  A 384 ( 4.7A)
 1.00A 2fumD-3eb0A:
17.4		 2fumD-3eb0A:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
GLY A  16
VAL A  23
LYS A  38
GLU A  50
TYR A 119
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
None
None
DRK  A 384 (-4.4A)
 0.49A 2ivuA-3eb0A:
23.3		 2ivuA-3eb0A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
TYR A 119
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.75A 2oiqA-3eb0A:
21.8		 2oiqA-3eb0A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
TYR A 119
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.93A 2pl0A-3eb0A:
20.8		 2pl0A-3eb0A:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A 305
MET A 140
LEU A 301
VAL A 154
LEU A 150
 None
 1.22A 3a51D-3eb0A:
undetectable		 3a51D-3eb0A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 LEU A  15
VAL A  23
LYS A  38
LEU A 173
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 (-4.4A)
 0.38A 3cs9D-3eb0A:
20.6		 3cs9D-3eb0A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
GLY A  16
GLY A  18
GLY A  21
VAL A  23
ALA A  36
MET A 117
TYR A 119
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
None
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
 0.73A 3fupA-3eb0A:
23.7		 3fupA-3eb0A:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_A_MI1A1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
GLY A  16
VAL A  23
ALA A  36
LYS A  38
MET A 117
TYR A 119
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
None
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.75A 3fupA-3eb0A:
23.7		 3fupA-3eb0A:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
GLY A  16
GLY A  18
ALA A  36
LYS A  38
MET A 117
TYR A 119
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
None
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.81A 3fupB-3eb0A:
23.7		 3fupB-3eb0A:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 CYH A 163
SER A 159
TYR A 359
ILE A 167
ILE A  62
 None
 1.40A 3g8iA-3eb0A:
undetectable		 3g8iA-3eb0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 CYH A 163
SER A 159
TYR A 359
ILE A 228
ILE A  62
 None
 1.19A 3g8iA-3eb0A:
undetectable		 3g8iA-3eb0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.73A 3gvuA-3eb0A:
21.3		 3gvuA-3eb0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
GLY A  16
VAL A  23
ALA A  36
LYS A  38
MET A 117
TYR A 119
ASP A 185
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
DRK  A 384 (-3.5A)
None
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.93A 3lxkA-3eb0A:
23.5		 3lxkA-3eb0A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
MET A 117
TYR A 119
LEU A 173
ASP A 185
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.96A 3lxkA-3eb0A:
23.5		 3lxkA-3eb0A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
ILE A  63
TYR A 119
LEU A 173
ASP A 185
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.79A 3lxnA-3eb0A:
23.6		 3lxnA-3eb0A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 SER A 362
SER A 159
LEU A  57
ASP A  58
 None
 0.86A 3m0wE-3eb0A:
undetectable
3m0wF-3eb0A:
undetectable
3m0wG-3eb0A:
undetectable
3m0wH-3eb0A:
undetectable		 3m0wE-3eb0A:
12.27
3m0wF-3eb0A:
12.27
3m0wG-3eb0A:
12.27
3m0wH-3eb0A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.65A 3ms9A-3eb0A:
20.9		 3ms9A-3eb0A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.64A 3mssA-3eb0A:
21.0		 3mssA-3eb0A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.63A 3mssC-3eb0A:
21.0		 3mssC-3eb0A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.71A 3pyyA-3eb0A:
21.4		 3pyyA-3eb0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.73A 3pyyB-3eb0A:
21.3		 3pyyB-3eb0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ARG A 152
SER A 144
ILE A 145
PHE A 354
ALA A 321
 None
 1.25A 3ua1A-3eb0A:
undetectable		 3ua1A-3eb0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 ILE A 228
GLY A 229
PHE A 325
LEU A 301
 None
 0.87A 3v7pA-3eb0A:
undetectable		 3v7pA-3eb0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 ILE A  53
MET A  54
LEU A  57
ILE A  62
ILE A  63
TYR A 119
 None
None
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.56A 3zosA-3eb0A:
21.1		 3zosA-3eb0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 LEU A  15
ILE A  53
MET A  54
LEU A  57
ILE A  62
TYR A 119
 DRK  A 384 (-3.8A)
None
None
None
None
DRK  A 384 (-4.4A)
 0.50A 3zosB-3eb0A:
21.0		 3zosB-3eb0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
LEU A 173
CYH A 184
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
DRK  A 384 ( 3.8A)
 0.68A 4ag8A-3eb0A:
21.0		 4ag8A-3eb0A:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
GLU A  50
ILE A  53
MET A  54
ILE A  63
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.64A 4bkjA-3eb0A:
20.8		 4bkjA-3eb0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
GLU A  50
ILE A  53
MET A  54
TYR A 119
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.81A 4bkjA-3eb0A:
20.8		 4bkjA-3eb0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
GLU A  50
ILE A  53
MET A  54
ILE A  63
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.78A 4bkjB-3eb0A:
20.9		 4bkjB-3eb0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 11 LEU A  15
GLY A  16
GLY A  18
VAL A  23
ALA A  36
TYR A 119
 DRK  A 384 (-3.8A)
DRK  A 384 ( 4.4A)
None
None
DRK  A 384 (-3.5A)
DRK  A 384 (-4.4A)
 0.81A 4ckiA-3eb0A:
23.7		 4ckiA-3eb0A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 VAL A  23
ALA A  36
GLU A  50
ILE A  53
MET A  54
TYR A 119
LEU A 173
 None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.72A 4csvA-3eb0A:
22.3		 4csvA-3eb0A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A 162
SER A 227
ILE A 167
ASN A 171
LEU A 183
 None
None
None
DRK  A 384 ( 4.6A)
None
 0.83A 4gh8A-3eb0A:
undetectable		 4gh8A-3eb0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 8 GLY A  18
VAL A  23
ALA A  36
LYS A  38
MET A 117
 None
None
DRK  A 384 (-3.5A)
None
DRK  A 384 (-3.8A)
 0.57A 4l9iB-3eb0A:
24.3		 4l9iB-3eb0A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
TYR A 119
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
 0.64A 4mxoA-3eb0A:
23.1		 4mxoA-3eb0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 VAL A  23
ALA A  36
THR A 123
LEU A 173
 None
DRK  A 384 (-3.5A)
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.64A 4o0uA-3eb0A:
19.4		 4o0uA-3eb0A:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 6 LEU A  15
VAL A  23
ALA A  36
THR A 123
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.81A 4o0wA-3eb0A:
25.7		 4o0wA-3eb0A:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 8 VAL A  23
ALA A  36
ASN A 171
LEU A 173
ASP A 185
 None
DRK  A 384 (-3.5A)
DRK  A 384 ( 4.6A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 4.7A)
 0.59A 4ogrA-3eb0A:
30.0		 4ogrA-3eb0A:
28.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 LEU A  15
VAL A  23
LYS A  38
ILE A  62
 DRK  A 384 (-3.8A)
None
None
None
 0.63A 4tyjA-3eb0A:
21.2		 4tyjA-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 10 LEU A  15
VAL A  23
GLU A  50
ILE A  62
VAL A 115
TYR A 119
 DRK  A 384 (-3.8A)
None
None
None
None
DRK  A 384 (-4.4A)
 0.60A 4u0iA-3eb0A:
20.9		 4u0iA-3eb0A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 VAL A  23
LYS A  38
MET A  54
ILE A  63
 None
None
None
DRK  A 384 ( 4.5A)
 0.73A 4uxqA-3eb0A:
21.0		 4uxqA-3eb0A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 LEU A  15
VAL A  23
LYS A  38
ILE A  63
TYR A 119
ILE A  62
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
None
 1.17A 4v01A-3eb0A:
20.3		 4v01A-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 9 LEU A  15
VAL A  23
LYS A  38
ILE A  63
TYR A 119
LEU A 173
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.80A 4v01A-3eb0A:
20.3		 4v01A-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 9 LEU A  15
VAL A  23
LYS A  38
ILE A  63
TYR A 119
LEU A 173
ILE A  62
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
None
 1.43A 4v01B-3eb0A:
20.8		 4v01B-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 LYS A  38
MET A  54
ILE A  63
LEU A 173
 None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.67A 4v04A-3eb0A:
20.4		 4v04A-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 LYS A  38
MET A  54
ILE A  63
TYR A 119
 None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.70A 4v04A-3eb0A:
20.4		 4v04A-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 10 LEU A  15
VAL A  23
LYS A  38
ILE A  63
TYR A 119
LEU A 173
ILE A  62
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
None
 1.24A 4v04B-3eb0A:
20.8		 4v04B-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 10 LEU A  15
VAL A  23
LYS A  38
MET A  54
ILE A  63
TYR A 119
LEU A 173
 DRK  A 384 (-3.8A)
None
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.82A 4v04B-3eb0A:
20.8		 4v04B-3eb0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 LEU A  15
ALA A  36
MET A 117
LEU A 173
 DRK  A 384 (-3.8A)
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
 0.67A 4wboB-3eb0A:
24.3		 4wboB-3eb0A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 LEU A  15
ALA A  36
MET A 117
LEU A 173
 DRK  A 384 (-3.8A)
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
 0.67A 4wboC-3eb0A:
24.5		 4wboC-3eb0A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 ILE A 305
HIS A 164
LEU A 183
LEU A 150
 None
 1.02A 4xo7A-3eb0A:
undetectable		 4xo7A-3eb0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
ILE A  63
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
 0.71A 5bvwA-3eb0A:
12.3		 5bvwA-3eb0A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		8 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
TYR A 119
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.83A 5bvwA-3eb0A:
12.3		 5bvwA-3eb0A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 PRO A 295
SER A 144
HIS A 322
PHE A 325
ASP A 300
 None
 1.15A 5eenA-3eb0A:
undetectable		 5eenA-3eb0A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 PRO A 295
HIS A 322
PHE A 325
ASP A 300
LEU A 297
 None
 1.45A 5eenB-3eb0A:
undetectable		 5eenB-3eb0A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 PRO A 295
SER A 144
PHE A 325
ASP A 300
LEU A 297
 None
 1.47A 5eenB-3eb0A:
undetectable		 5eenB-3eb0A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 ALA A  36
ILE A  63
TYR A 119
CYH A 184
PHE A 186
GLY A 187
 DRK  A 384 (-3.5A)
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 3.8A)
None
None
 1.09A 5hesA-3eb0A:
5.8		 5hesA-3eb0A:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 VAL A  23
ALA A  36
ILE A  63
TYR A 119
CYH A 184
PHE A 186
 None
DRK  A 384 (-3.5A)
DRK  A 384 ( 4.5A)
DRK  A 384 (-4.4A)
DRK  A 384 ( 3.8A)
None
 1.02A 5hesA-3eb0A:
5.8		 5hesA-3eb0A:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 7 GLY A  16
LEU A  65
ASP A 185
PHE A 186
 DRK  A 384 ( 4.4A)
None
DRK  A 384 ( 4.7A)
None
 0.82A 5hieB-3eb0A:
6.6		 5hieB-3eb0A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 9 LEU A 172
ILE A 228
ILE A  62
GLU A 118
VAL A 120
 None
None
None
None
DRK  A 384 (-4.5A)
 1.42A 5igzA-3eb0A:
7.5		 5igzA-3eb0A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ASP A 224
ILE A 157
LEU A 183
GLU A 360
GLY A 155
 None
 1.36A 5il1A-3eb0A:
undetectable		 5il1A-3eb0A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 10 ILE A 157
LEU A 183
ILE A 228
ILE A 167
ILE A 223
 None
 0.97A 5mvmD-3eb0A:
undetectable
5mvmE-3eb0A:
undetectable		 5mvmD-3eb0A:
11.70
5mvmE-3eb0A:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 10 LEU A  15
VAL A  23
ALA A  36
MET A 117
TYR A 119
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
DRK  A 384 (-3.8A)
DRK  A 384 (-4.4A)
DRK  A 384 (-4.4A)
 0.70A 5n3hA-3eb0A:
25.7		 5n3hA-3eb0A:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 5 LEU A  15
VAL A  23
MET A 117
CYH A 184
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.8A)
DRK  A 384 ( 3.8A)
 0.74A 5te0A-3eb0A:
24.1		 5te0A-3eb0A:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		5 / 9 LEU A  15
VAL A  23
LYS A  38
ILE A  63
ASP A 185
 DRK  A 384 (-3.8A)
None
None
DRK  A 384 ( 4.5A)
DRK  A 384 ( 4.7A)
 0.93A 5yf9X-3eb0A:
29.2		 5yf9X-3eb0A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
GLU A  50
MET A  54
TYR A 119
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
DRK  A 384 (-4.4A)
 0.55A 5zv2A-3eb0A:
20.5		 5zv2A-3eb0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		6 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
None
 0.53A 5zv2B-3eb0A:
20.4		 5zv2B-3eb0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 VAL A 127
LEU A 328
ARG A 152
PRO A 351
 None
 1.32A 6brdB-3eb0A:
undetectable		 6brdB-3eb0A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 3eb0 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Cryptosporidium
parvum) 		7 / 12 LEU A  15
VAL A  23
ALA A  36
LYS A  38
GLU A  50
MET A  54
LEU A 173
 DRK  A 384 (-3.8A)
None
DRK  A 384 (-3.5A)
None
None
None
DRK  A 384 (-4.4A)
 0.68A 6hd6B-3eb0A:
20.8		 6hd6B-3eb0A:
13.26