SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 3eb6 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A 555
VAL A 568
THR A 601
 None
 0.87A 3cyxA-3eb6A:
undetectable		 3cyxA-3eb6A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3eb6 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 6 PHE A 569
ILE A 595
ARG A 586
VAL A 559
 None
 1.27A 4mk4B-3eb6A:
undetectable		 4mk4B-3eb6A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eb6 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 GLN A 552
ILE A 590
HIS A 574
 None
ZN  A1002 ( 4.9A)
ZN  A1002 (-2.8A)
 0.62A 5z12B-3eb6A:
undetectable		 5z12B-3eb6A:
22.89