SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 7 TYR A 293
ASP A 289
PHE A 609
ARG A 567
 None
 1.48A 1b2iA-3eb7A:
undetectable		 1b2iA-3eb7A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 HIS A 532
THR A 275
LYS A 337
ASP A 537
GLY A 535
 None
 1.43A 1d4fC-3eb7A:
undetectable		 1d4fC-3eb7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 ASP A 212
LEU A 205
LEU A 209
 None
 0.56A 1ikeA-3eb7A:
undetectable		 1ikeA-3eb7A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 7 GLU A  66
LEU A 121
MET A 274
GLU A 273
 None
 1.06A 1linA-3eb7A:
undetectable		 1linA-3eb7A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 11 LEU A 152
VAL A  89
ILE A  92
LEU A 175
LEU A 209
 None
 1.22A 1mrqA-3eb7A:
undetectable		 1mrqA-3eb7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 ASP A 212
LEU A 205
LEU A 209
 None
 0.63A 1np1B-3eb7A:
undetectable		 1np1B-3eb7A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 LYS A 437
TYR A 475
PRO A 434
 None
 1.20A 2j9cC-3eb7A:
undetectable		 2j9cC-3eb7A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 ILE A 238
TYR A 293
GLN A 513
ARG A 567
TYR A 604
 None
 1.30A 2ya7A-3eb7A:
undetectable		 2ya7A-3eb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 ILE A 238
TYR A 293
GLN A 513
ARG A 567
TYR A 604
 None
 1.32A 2ya7B-3eb7A:
undetectable		 2ya7B-3eb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 ILE A 238
TYR A 293
GLN A 513
ARG A 567
TYR A 604
 None
 1.30A 2ya7D-3eb7A:
undetectable		 2ya7D-3eb7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 6 THR A 180
PHE A 179
LEU A 237
LEU A 210
 None
 1.13A 3bgdA-3eb7A:
undetectable		 3bgdA-3eb7A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 5 ILE A 238
ARG A 565
THR A 292
GLU A 647
 None
 1.33A 3ny4A-3eb7A:
undetectable		 3ny4A-3eb7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 10 TYR A 481
VAL A 482
TYR A 383
ILE A 348
ILE A 397
 None
 1.35A 3vriA-3eb7A:
undetectable
3vriC-3eb7A:
undetectable		 3vriA-3eb7A:
17.20
3vriC-3eb7A:
2.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 8 ILE A 397
GLY A 398
PHE A 399
VAL A 427
SER A 458
 None
 1.30A 4acbB-3eb7A:
undetectable
4acbC-3eb7A:
undetectable		 4acbB-3eb7A:
21.42
4acbC-3eb7A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 8 GLU A 647
THR A 297
ALA A 299
LEU A 301
 None
 0.83A 4iizB-3eb7A:
undetectable		 4iizB-3eb7A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 8 GLU A 647
THR A 297
ALA A 299
LEU A 301
 None
 0.82A 4ik6B-3eb7A:
undetectable		 4ik6B-3eb7A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 8 ILE A 126
GLU A 137
PRO A 194
VAL A 188
 None
 0.69A 4jltA-3eb7A:
undetectable		 4jltA-3eb7A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 5 GLY A  78
LEU A 103
ILE A 281
LEU A 208
 None
 0.88A 4o8fA-3eb7A:
undetectable		 4o8fA-3eb7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA701_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 5 TYR A  96
ASP A 212
MET A 290
TYR A 288
 None
 1.48A 4p7nA-3eb7A:
0.0		 4p7nA-3eb7A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_A_PARA500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 10 PHE A 607
THR A 283
SER A 242
ASP A 280
GLY A 535
 None
 1.04A 4qb9A-3eb7A:
0.0		 4qb9A-3eb7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_C_PARC500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 10 PHE A 607
THR A 283
SER A 242
ASP A 280
GLY A 535
 None
 1.19A 4qb9C-3eb7A:
0.0		 4qb9C-3eb7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 PHE A 607
THR A 283
SER A 242
ASP A 280
GLY A 535
 None
 1.10A 4qb9E-3eb7A:
0.8		 4qb9E-3eb7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 ASP A 280
LEU A 279
PHE A 340
GLY A 536
ARG A 478
 None
 1.24A 4retA-3eb7A:
3.7		 4retA-3eb7A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 7 VAL A  89
ILE A  92
LEU A 175
LEU A 209
 None
 0.90A 4xo7A-3eb7A:
undetectable		 4xo7A-3eb7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 VAL A 585
THR A 583
ARG A 580
 None
 0.60A 5b2sB-3eb7A:
undetectable		 5b2sB-3eb7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 VAL A 585
THR A 583
ARG A 580
 None
 0.65A 5b2tB-3eb7A:
1.8		 5b2tB-3eb7A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 6 PHE A 493
PHE A 326
VAL A 490
ASP A 308
 None
 1.26A 5hesA-3eb7A:
undetectable		 5hesA-3eb7A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 12 ALA A 519
ARG A 478
THR A 496
PHE A 342
ILE A 374
 None
 1.30A 5hgcA-3eb7A:
undetectable		 5hgcA-3eb7A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 ASP A 501
PHE A 340
ARG A 478
 None
 1.16A 5yw0A-3eb7A:
undetectable		 5yw0A-3eb7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		3 / 3 TYR A 249
ARG A 250
THR A 251
 None
 1.03A 5z84J-3eb7A:
undetectable		 5z84J-3eb7A:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		4 / 6 TYR A 293
ASP A 644
GLN A 300
THR A 292
 None
 1.38A 6djzA-3eb7A:
undetectable		 6djzA-3eb7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 10 PHE A 429
LEU A 479
GLY A 398
ILE A 397
ILE A 369
 None
 1.18A 6ebpB-3eb7A:
undetectable		 6ebpB-3eb7A:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1
(Bacillus
thuringiensis) 		5 / 10 PHE A 429
LEU A 479
GLY A 398
ILE A 397
ILE A 369
 None
 1.18A 6ebpC-3eb7A:
undetectable		 6ebpC-3eb7A:
8.84