SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ebc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT3_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	3ebc	TYPE-2 RESTRICTION ENZYME HINCII (Haemophilus influenzae)	4 / 7	LEU A 79 LEU A 60 TYR A 123 LEU A 86	None	1.05A	1kt3A-3ebcA: undetectable	1kt3A-3ebcA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B9E_A_SAMA1201_0 (NOL1/NOP2/SUN DOMAIN FAMILY, MEMBER 5 ISOFORM 2)	3ebc	TYPE-2 RESTRICTION ENZYME HINCII (Haemophilus influenzae)	5 / 12	ASN A 132 LEU A 215 ASP A 214 ARG A 213 SER A 186	None	1.28A	2b9eA-3ebcA: undetectable	2b9eA-3ebcA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZB7_A_NCAA901_0 (PROSTAGLANDIN REDUCTASE 2)	3ebc	TYPE-2 RESTRICTION ENZYME HINCII (Haemophilus influenzae)	4 / 5	ILE A 143 MET A 155 LEU A 125 LEU A 88	None	1.06A	2zb7A-3ebcA: undetectable	2zb7A-3ebcA: 18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A84_A_DXCA1161_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	3ebc	TYPE-2 RESTRICTION ENZYME HINCII (Haemophilus influenzae)	5 / 12	PHE A 210 PRO A 140 LEU A 126 VAL A 41 SER A 186	None	1.48A	4a84A-3ebcA: undetectable	4a84A-3ebcA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_B_GMJB301_1 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	3ebc	TYPE-2 RESTRICTION ENZYME HINCII (Haemophilus influenzae)	4 / 6	TYR A 8 ASP A 172 VAL A 183 ALA A 188	None	1.25A	6djzB-3ebcA: undetectable	6djzB-3ebcA: 21.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KT3_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","3ebc","TYPE-2 RESTRICTION ENZYME HINCII","Haemophilus influenzae",4,"LEU A  79;LEU A  60;TYR A 123;LEU A  86","None","1.05A","1kt3A-3ebcA:undetectable","1kt3A-3ebcA:21.27"],["2B9E_A_SAMA1201_0","NOL1\/NOP2\/SUN DOMAIN FAMILY, MEMBER 5 ISOFORM 2","3ebc","TYPE-2 RESTRICTION ENZYME HINCII","Haemophilus influenzae",5,"ASN A 132;LEU A 215;ASP A 214;ARG A 213;SER A 186","None","1.28A","2b9eA-3ebcA:undetectable","2b9eA-3ebcA:21.26"],["2ZB7_A_NCAA901_0","PROSTAGLANDIN REDUCTASE 2","3ebc","TYPE-2 RESTRICTION ENZYME HINCII","Haemophilus influenzae",4,"ILE A 143;MET A 155;LEU A 125;LEU A  88","None","1.06A","2zb7A-3ebcA:undetectable","2zb7A-3ebcA:18.81"],["4A84_A_DXCA1161_0","MAJOR POLLEN ALLERGEN BET V 1-A","3ebc","TYPE-2 RESTRICTION ENZYME HINCII","Haemophilus influenzae",5,"PHE A 210;PRO A 140;LEU A 126;VAL A  41;SER A 186","None","1.48A","4a84A-3ebcA:undetectable","4a84A-3ebcA:18.15"],["6DJZ_B_GMJB301_1","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","3ebc","TYPE-2 RESTRICTION ENZYME HINCII","Haemophilus influenzae",4,"TYR A   8;ASP A 172;VAL A 183;ALA A 188","None","1.25A","6djzB-3ebcA:undetectable","6djzB-3ebcA:21.38"]]