SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ebl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ASP A 187
GLY A 186
GLY A 185
LEU A 352
PHE A 113
 None
 0.95A 1bx4A-3eblA:
undetectable		 1bx4A-3eblA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 6 ALA A 269
SER A 195
ARG A 251
LEU A 259
 None
None
GA4  A 401 (-3.8A)
None
 1.23A 1gahA-3eblA:
undetectable		 1gahA-3eblA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ILE A 133
SER A 293
GLY A 121
SER A 198
TYR A 134
 None
None
GA4  A 401 ( 4.6A)
GA4  A 401 (-2.6A)
GA4  A 401 (-4.8A)
 1.05A 1kiaA-3eblA:
2.0		 1kiaA-3eblA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ILE A 133
SER A 293
GLY A 122
SER A 198
TYR A 134
 None
None
GA4  A 401 (-2.9A)
GA4  A 401 (-2.6A)
GA4  A 401 (-4.8A)
 1.00A 1kiaA-3eblA:
2.0		 1kiaA-3eblA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 TYR A  31
SER A 128
HIS A 120
ILE A  24
TYR A 134
 MPD  A 501 ( 4.9A)
None
None
GA4  A 401 (-4.2A)
GA4  A 401 (-4.8A)
 1.31A 1xvaB-3eblA:
2.7		 1xvaB-3eblA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 8 TYR A  31
ILE A 133
TYR A 134
GLY A 121
 MPD  A 501 ( 4.9A)
None
GA4  A 401 (-4.8A)
GA4  A 401 ( 4.6A)
 0.93A 2gssA-3eblA:
undetectable		 2gssA-3eblA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 8 TYR A  31
ILE A 133
TYR A 134
GLY A 121
 MPD  A 501 ( 4.9A)
None
GA4  A 401 (-4.8A)
GA4  A 401 ( 4.6A)
 0.93A 2gssB-3eblA:
undetectable		 2gssB-3eblA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 5 LEU A 224
GLY A 201
ILE A 290
ILE A 291
 None
 0.79A 2q9rA-3eblA:
undetectable		 2q9rA-3eblA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 8 ASP A  71
ILE A  70
VAL A  78
VAL A 152
 None
 0.80A 3fi0I-3eblA:
undetectable		 3fi0I-3eblA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 9 VAL A  74
ASP A  71
ILE A  70
VAL A  78
VAL A 152
 None
 1.05A 3fi0M-3eblA:
undetectable		 3fi0M-3eblA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 7 TYR A  31
ILE A 133
TYR A 134
GLY A 121
 MPD  A 501 ( 4.9A)
None
GA4  A 401 (-4.8A)
GA4  A 401 ( 4.6A)
 0.94A 3gssB-3eblA:
undetectable		 3gssB-3eblA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 7 GLY A 121
MET A 341
GLY A 327
PHE A 328
 GA4  A 401 ( 4.6A)
None
GA4  A 401 (-2.9A)
None
 0.87A 3ko0M-3eblA:
undetectable
3ko0P-3eblA:
0.4		 3ko0M-3eblA:
14.95
3ko0P-3eblA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 7 TYR A 329
LEU A 348
LEU A 224
PHE A 118
 None
 1.09A 3nk2X-3eblA:
undetectable		 3nk2X-3eblA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 SER A 198
MET A 227
TYR A 134
SER A 131
PHE A 124
 GA4  A 401 (-2.6A)
None
GA4  A 401 (-4.8A)
None
None
 1.40A 3ugrA-3eblA:
undetectable		 3ugrA-3eblA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ILE A 203
GLY A 196
ASP A 197
TYR A 154
ASN A 153
 None
None
GA4  A 401 (-4.2A)
None
None
 0.97A 4a81A-3eblA:
undetectable		 4a81A-3eblA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 8 LEU A 137
CYH A 138
PHE A 118
TYR A  81
 None
 1.00A 4j7uD-3eblA:
3.9		 4j7uD-3eblA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 LEU A 137
CYH A 138
PHE A 141
TYR A  81
GLY A 201
 None
 1.38A 4j7xF-3eblA:
3.5		 4j7xF-3eblA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 TYR A 134
GLY A 200
GLY A 196
SER A 151
ALA A 165
 GA4  A 401 (-4.8A)
None
None
None
None
 1.11A 4krhB-3eblA:
3.3		 4krhB-3eblA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 8 TYR A 166
PHE A 124
GLY A 229
ASN A 202
 None
 0.87A 4qoiA-3eblA:
3.4
4qoiB-3eblA:
undetectable		 4qoiA-3eblA:
20.38
4qoiB-3eblA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 10 ASP A 197
PHE A 328
GLU A 339
VAL A 340
ILE A 344
 GA4  A 401 (-4.2A)
None
None
None
None
 1.45A 4qt3A-3eblA:
undetectable		 4qt3A-3eblA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		3 / 3 LEU A 248
ARG A 265
ARG A 301
 None
NO3  A 602 (-3.3A)
None
 0.96A 4yiaB-3eblA:
undetectable		 4yiaB-3eblA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 7 ILE A 117
ASP A 197
GLY A 200
PHE A 119
TYR A 329
 None
GA4  A 401 (-4.2A)
None
None
None
 1.49A 5h3aA-3eblA:
undetectable		 5h3aA-3eblA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		3 / 3 SER A 293
ALA A 324
THR A 334
 None
 0.76A 5n0xB-3eblA:
1.1		 5n0xB-3eblA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ALA A 129
GLY A 122
GLY A 169
ALA A 172
SER A 199
 None
GA4  A 401 (-2.9A)
None
None
None
 0.94A 5w4zA-3eblA:
undetectable		 5w4zA-3eblA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		5 / 12 ALA A 129
GLY A 122
GLY A 169
ALA A 172
SER A 199
 None
GA4  A 401 (-2.9A)
None
None
None
 0.95A 5w4zB-3eblA:
undetectable		 5w4zB-3eblA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3ebl GIBBERELLIN RECEPTOR
GID1
(Oryza
sativa) 		4 / 5 ARG A 278
ARG A 279
GLY A 281
ASP A 312
 None
 1.11A 6dwjB-3eblA:
0.8
6dwjD-3eblA:
0.8		 6dwjB-3eblA:
21.14
6dwjD-3eblA:
21.14