SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ebt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA205_1 (CARDIAC TROPONIN C)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	5 / 12	ILE A 65 PHE A 15 LEU A 70 MET A 68 PHE A 116	None UNL A 133 ( 4.4A) UNL A 133 (-4.9A) UNL A 132 ( 3.9A) UNL A 133 (-4.8A)	1.04A	1dtlA-3ebtA: undetectable	1dtlA-3ebtA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FSL_A_NIOA145_1 (LEGHEMOGLOBIN A)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	4 / 8	ILE A 65 PHE A 57 HIS A 35 VAL A 90	None None UNL A 133 (-4.0A) None	0.86A	1fslA-3ebtA: undetectable	1fslA-3ebtA: 24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FSL_B_NIOB145_1 (LEGHEMOGLOBIN A)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	4 / 8	ILE A 65 PHE A 57 HIS A 35 VAL A 90	None None UNL A 133 (-4.0A) None	0.85A	1fslB-3ebtA: undetectable	1fslB-3ebtA: 24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F5Z_A_BEZA302_0 (HALOALKANE DEHALOGENASE)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	4 / 8	ASP A 118 VAL A 61 LEU A 70 HIS A 35	UNL A 133 (-3.6A) None UNL A 133 (-4.9A) UNL A 133 (-4.0A)	1.23A	4f5zA-3ebtA: undetectable	4f5zA-3ebtA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA503_1 (CYTOCHROME P450 2C9)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	4 / 5	PRO A 72 GLY A 86 THR A 87 LYS A 101	None	1.07A	5x23A-3ebtA: undetectable	5x23A-3ebtA: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA502_1 (CYTOCHROME P450 2C9)	3ebt	UNCHARACTERIZED NTF2-LIKE PROTEIN (Burkholderia pseudomallei)	4 / 6	PRO A 72 GLY A 86 THR A 87 LYS A 101	None	1.05A	5xxiA-3ebtA: undetectable	5xxiA-3ebtA: 14.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA205_1","CARDIAC TROPONIN C","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",5,"ILE A  65;PHE A  15;LEU A  70;MET A  68;PHE A 116","None;UNL A 133 ( 4.4A);UNL A 133 (-4.9A);UNL A 132 ( 3.9A);UNL A 133 (-4.8A)","1.04A","1dtlA-3ebtA:undetectable","1dtlA-3ebtA:22.15"],["1FSL_A_NIOA145_1","LEGHEMOGLOBIN A","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",4,"ILE A  65;PHE A  57;HIS A  35;VAL A  90","None;None;UNL A 133 (-4.0A);None","0.86A","1fslA-3ebtA:undetectable","1fslA-3ebtA:24.84"],["1FSL_B_NIOB145_1","LEGHEMOGLOBIN A","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",4,"ILE A  65;PHE A  57;HIS A  35;VAL A  90","None;None;UNL A 133 (-4.0A);None","0.85A","1fslB-3ebtA:undetectable","1fslB-3ebtA:24.84"],["4F5Z_A_BEZA302_0","HALOALKANE DEHALOGENASE","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",4,"ASP A 118;VAL A  61;LEU A  70;HIS A  35","UNL A 133 (-3.6A);None;UNL A 133 (-4.9A);UNL A 133 (-4.0A)","1.23A","4f5zA-3ebtA:undetectable","4f5zA-3ebtA:18.53"],["5X23_A_LSNA503_1","CYTOCHROME P450 2C9","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",4,"PRO A  72;GLY A  86;THR A  87;LYS A 101","None","1.07A","5x23A-3ebtA:undetectable","5x23A-3ebtA:15.71"],["5XXI_A_LSNA502_1","CYTOCHROME P450 2C9","3ebt","UNCHARACTERIZED NTF2-LIKE PROTEIN","Burkholderia pseudomallei",4,"PRO A  72;GLY A  86;THR A  87;LYS A 101","None","1.05A","5xxiA-3ebtA:undetectable","5xxiA-3ebtA:14.16"]]