SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 THR A  36
TYR A  44
TYR A  22
CYH A  25
 None
 1.40A 2xz5A-3ebyA:
undetectable
2xz5C-3ebyA:
undetectable		 2xz5A-3ebyA:
19.91
2xz5C-3ebyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		3 / 3 TYR A  44
ASP A 131
HIS A  89
 None
 0.88A 3e23A-3ebyA:
undetectable		 3e23A-3ebyA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 6 ARG A 145
ASP A  16
ASN A  19
TYR A  22
 None
 1.46A 3wfaA-3ebyA:
undetectable
3wfaB-3ebyA:
undetectable		 3wfaA-3ebyA:
13.23
3wfaB-3ebyA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		5 / 12 ILE A 162
TYR A 129
HIS A  89
ALA A 108
ILE A 123
 None
 1.09A 5igvA-3ebyA:
3.4		 5igvA-3ebyA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 TYR A  22
THR A  36
CYH A  42
LEU A  69
 None
 1.41A 5kxiA-3ebyA:
undetectable
5kxiB-3ebyA:
undetectable		 5kxiA-3ebyA:
17.44
5kxiB-3ebyA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3eby BETA SUBUNIT OF A
PUTATIVE
AROMATIC-RING-HYDROX
YLATING DIOXYGENASE
(Novosphingobium
aromaticivorans) 		4 / 8 TYR A  22
THR A  36
CYH A  42
LEU A  69
 None
 1.36A 5kxiD-3ebyA:
undetectable
5kxiE-3ebyA:
undetectable		 5kxiD-3ebyA:
17.44
5kxiE-3ebyA:
17.12