SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ech'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3ech 25-MER FRAGMENT OF
PROTEIN ARMR
MULTIDRUG RESISTANCE
OPERON REPRESSOR
(Pseudomonas
aeruginosa) 		3 / 3 TRP C  45
HIS A 116
MET A 112
 None
 1.49A 1l5qB-3echC:
undetectable		 1l5qB-3echC:
3.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ech MULTIDRUG RESISTANCE
OPERON REPRESSOR
25-MER FRAGMENT OF
PROTEIN ARMR
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		3 / 3 ARG C  42
LYS A  44
ARG C  41
 None
 1.26A 3w1wA-3echC:
undetectable
3w1wB-3echC:
undetectable		 3w1wA-3echC:
5.67
3w1wB-3echC:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ech MULTIDRUG RESISTANCE
OPERON REPRESSOR
25-MER FRAGMENT OF
PROTEIN ARMR
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		3 / 3 ARG C  41
ARG C  42
LYS A  44
 None
 1.37A 3w1wA-3echC:
undetectable
3w1wB-3echC:
undetectable		 3w1wA-3echC:
5.67
3w1wB-3echC:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3ech 25-MER FRAGMENT OF
PROTEIN ARMR
(Pseudomonas
aeruginosa) 		4 / 6 ASP C  46
ASN C  43
ALA C  44
TYR C  48
 None
 1.09A 4mdaA-3echC:
undetectable		 4mdaA-3echC:
9.30