SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ecq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 GLY A 772
ASN A 774
GLY A 769
VAL A 763
 None
 0.89A 1dbbH-3ecqA:
undetectable
1dbbL-3ecqA:
2.3		 1dbbH-3ecqA:
9.83
1dbbL-3ecqA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 ARG A1043
TYR A 889
ARG A 955
ASN A 953
 None
 1.38A 1f9gA-3ecqA:
5.9		 1f9gA-3ecqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 VAL A 370
LEU A 567
PHE A 421
THR A 424
PRO A 348
 None
 1.46A 1ia0B-3ecqA:
undetectable		 1ia0B-3ecqA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 PHE A 501
GLY A 469
SER A 826
THR A 829
 None
 1.21A 1icuC-3ecqA:
undetectable
1icuD-3ecqA:
undetectable		 1icuC-3ecqA:
9.53
1icuD-3ecqA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 PHE A 501
GLY A 469
SER A 826
THR A 829
 None
 1.17A 1icvA-3ecqA:
undetectable
1icvB-3ecqA:
undetectable		 1icvA-3ecqA:
9.53
1icvB-3ecqA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 GLU A 699
GLN A 770
VAL A 765
ASN A 696
 None
 1.33A 1jqdA-3ecqA:
2.8		 1jqdA-3ecqA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 THR A1392
GLY A1290
ASP A1407
TYR A1320
ALA A1364
 None
 1.39A 1oltA-3ecqA:
undetectable		 1oltA-3ecqA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ARG A1163
ASN A1161
GLN A 623
ASP A1254
 None
 1.26A 1p6kB-3ecqA:
undetectable		 1p6kB-3ecqA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 615
LEU A 680
ILE A 667
LEU A 754
ILE A 693
 None
 0.98A 1rb2A-3ecqA:
undetectable		 1rb2A-3ecqA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 615
LEU A 680
ILE A 667
LEU A 754
ILE A 693
 None
 1.01A 1rd7B-3ecqA:
undetectable		 1rd7B-3ecqA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 656
GLY A 619
ILE A 671
ALA A 622
SER A 654
 None
 1.12A 1ri4A-3ecqA:
undetectable		 1ri4A-3ecqA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 PHE A 367
ASN A 453
PHE A 347
SER A 449
 None
 1.01A 1rqpB-3ecqA:
undetectable		 1rqpB-3ecqA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A 367
ASN A 453
PHE A 347
SER A 449
 None
 1.04A 1rqpC-3ecqA:
undetectable		 1rqpC-3ecqA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A 367
ASN A 453
PHE A 347
SER A 449
 None
 1.03A 1rqpA-3ecqA:
undetectable		 1rqpA-3ecqA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 615
LEU A 680
ILE A 667
LEU A 754
ILE A 693
 None
 0.92A 1rx7A-3ecqA:
undetectable		 1rx7A-3ecqA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 LYS A 495
ALA A 531
LEU A 529
VAL A 542
 None
 1.02A 1sn5A-3ecqA:
undetectable		 1sn5A-3ecqA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 LYS A 495
ALA A 531
LEU A 529
VAL A 542
 None
 0.99A 1sn5C-3ecqA:
undetectable		 1sn5C-3ecqA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 11 LEU A 360
GLY A 464
ALA A 465
ASP A 485
VAL A 542
VAL A 458
 None
 1.47A 1t7jA-3ecqA:
undetectable		 1t7jA-3ecqA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 VAL A 370
LEU A 567
PHE A 421
THR A 424
PRO A 348
 None
 1.46A 1tubB-3ecqA:
undetectable		 1tubB-3ecqA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASN A 598
TRP A 512
GLN A 836
 None
 1.41A 1xoqA-3ecqA:
undetectable		 1xoqA-3ecqA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 PHE A1206
ARG A1210
ASN A1177
 None
 0.83A 1xzxX-3ecqA:
undetectable		 1xzxX-3ecqA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ALA A 580
ASN A 579
ILE A 591
ASP A 588
 None
CA  A2000 (-2.8A)
None
CA  A2000 (-2.3A)
 0.97A 1yc2A-3ecqA:
undetectable		 1yc2A-3ecqA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ALA A 580
ASN A 579
ILE A 591
ASP A 588
 None
CA  A2000 (-2.8A)
None
CA  A2000 (-2.3A)
 0.99A 1yc2D-3ecqA:
undetectable		 1yc2D-3ecqA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ARG A1163
ASN A1161
GLN A 623
ASP A1254
 None
 1.27A 1zzqB-3ecqA:
undetectable		 1zzqB-3ecqA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ARG A1163
ASN A1161
GLN A 623
ASP A1254
 None
 1.28A 1zzuB-3ecqA:
undetectable		 1zzuB-3ecqA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 615
LEU A 680
ILE A 667
LEU A 754
ILE A 693
 None
 0.91A 2d0kA-3ecqA:
undetectable		 2d0kA-3ecqA:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 140
THR A 138
VAL A 137
LEU A 150
 None
 1.03A 2e1qA-3ecqA:
undetectable		 2e1qA-3ecqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 140
THR A 138
VAL A 137
LEU A 150
 None
 1.02A 2e1qC-3ecqA:
undetectable		 2e1qC-3ecqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ALA A 580
ASN A 579
ILE A 591
ASP A 588
 None
CA  A2000 (-2.8A)
None
CA  A2000 (-2.3A)
 1.04A 2h4jA-3ecqA:
undetectable		 2h4jA-3ecqA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 771
ILE A 733
ALA A 735
TYR A 664
ARG A 746
 None
 1.24A 2japA-3ecqA:
undetectable		 2japA-3ecqA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 771
ILE A 733
ALA A 735
TYR A 664
ARG A 746
 None
 1.27A 2japC-3ecqA:
undetectable		 2japC-3ecqA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 771
ILE A 733
ALA A 735
TYR A 664
ARG A 746
 None
 1.19A 2japD-3ecqA:
undetectable		 2japD-3ecqA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A 150
GLY A 290
GLY A 211
VAL A 301
VAL A 299
 None
 0.96A 2nnkB-3ecqA:
undetectable		 2nnkB-3ecqA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 11 GLN A 255
ASP A 658
HIS A 694
ASP A 764
TRP A 867
 None
None
None
None
GOL  A2003 (-4.4A)
 1.23A 2owcA-3ecqA:
3.9		 2owcA-3ecqA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
ASP A 485
VAL A 542
VAL A 456
 None
 1.42A 2q63A-3ecqA:
undetectable		 2q63A-3ecqA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.14A 2q63A-3ecqA:
undetectable		 2q63A-3ecqA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 ARG A 231
ASN A 725
THR A 226
 None
 0.77A 2q63A-3ecqA:
undetectable		 2q63A-3ecqA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.17A 2q64B-3ecqA:
undetectable		 2q64B-3ecqA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 LEU A 758
LEU A 691
ILE A 761
ARG A 792
 None
 1.04A 2rlfB-3ecqA:
undetectable
2rlfC-3ecqA:
undetectable		 2rlfB-3ecqA:
2.83
2rlfC-3ecqA:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 TRP A 995
ILE A1029
LEU A 997
LEU A1031
 None
 1.03A 2rlfA-3ecqA:
undetectable
2rlfD-3ecqA:
undetectable		 2rlfA-3ecqA:
2.83
2rlfD-3ecqA:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ASP A1278
PRO A 702
THR A 700
GLY A 730
GLY A 723
 None
 1.19A 2uvnA-3ecqA:
undetectable		 2uvnA-3ecqA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A 367
ASN A 453
PHE A 347
SER A 449
 None
 1.05A 2v7uA-3ecqA:
undetectable		 2v7uA-3ecqA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 PHE A 367
ASN A 453
PHE A 347
SER A 449
 None
 1.04A 2v7uB-3ecqA:
undetectable		 2v7uB-3ecqA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VZS_A_GCSA1902_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLU A 655
SER A 654
ASP A 666
GLU A1261
TRP A1284
 None
 1.35A 2vzsA-3ecqA:
1.9		 2vzsA-3ecqA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VZS_B_GCSB1903_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLU A 655
SER A 654
ASP A 666
GLU A1261
TRP A1284
 None
 1.35A 2vzsB-3ecqA:
2.0		 2vzsB-3ecqA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 PHE A 367
ASN A 453
PHE A 347
 None
 0.59A 2zbuD-3ecqA:
undetectable		 2zbuD-3ecqA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 THR A1211
LEU A1108
VAL A1191
VAL A1142
 None
 1.03A 2zuhA-3ecqA:
undetectable		 2zuhA-3ecqA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ARG A 140
THR A 138
VAL A 137
LEU A 150
 None
 0.96A 3ax7A-3ecqA:
undetectable		 3ax7A-3ecqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 LYS A 130
GLN A 133
GLY A 135
LEU A 150
 None
 1.11A 3bjwE-3ecqA:
undetectable		 3bjwE-3ecqA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 615
ILE A 671
ILE A 667
LEU A 754
ILE A 693
 None
 0.88A 3clbC-3ecqA:
undetectable		 3clbC-3ecqA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 11 ALA A 531
GLY A 500
SER A 457
VAL A 456
ALA A 454
 None
 0.94A 3dcmX-3ecqA:
3.1		 3dcmX-3ecqA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 GLU A 323
GLY A 321
THR A 320
GLU A 319
 None
 1.07A 3e9xA-3ecqA:
undetectable		 3e9xA-3ecqA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
ASP A 485
VAL A 542
VAL A 456
 None
 1.41A 3jw2B-3ecqA:
undetectable		 3jw2B-3ecqA:
5.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.17A 3k4vB-3ecqA:
undetectable		 3k4vB-3ecqA:
4.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 LYS A1085
ASN A1090
HIS A1160
ILE A1083
 None
 1.35A 3kp6A-3ecqA:
undetectable
3kp6B-3ecqA:
undetectable		 3kp6A-3ecqA:
7.33
3kp6B-3ecqA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 ARG A1341
ASP A1170
GLN A1096
 None
 0.93A 3lcvB-3ecqA:
undetectable		 3lcvB-3ecqA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 TYR A 847
SER A 860
LEU A 814
ASP A 813
 None
None
None
GOL  A2003 (-3.6A)
 1.12A 3lsfH-3ecqA:
undetectable		 3lsfH-3ecqA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 449
PHE A 347
VAL A 410
PRO A 348
PHE A 421
 None
 1.48A 3nbrA-3ecqA:
0.0		 3nbrA-3ecqA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 862
ARG A 870
ASP A 173
 GOL  A2003 (-3.5A)
GOL  A2003 (-4.7A)
None
 1.28A 3o7wA-3ecqA:
undetectable		 3o7wA-3ecqA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 TYR A1060
ASP A 631
ASP A1091
 None
 0.94A 3ou7B-3ecqA:
undetectable		 3ou7B-3ecqA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 10 LEU A 360
GLY A 464
ALA A 465
ASP A 485
VAL A 542
VAL A 456
 None
 1.49A 3oy4B-3ecqA:
undetectable		 3oy4B-3ecqA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ARG A1269
ALA A1322
LEU A1354
ASP A1325
 None
 0.79A 3qj7A-3ecqA:
undetectable
3qj7D-3ecqA:
undetectable		 3qj7A-3ecqA:
10.98
3qj7D-3ecqA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 4 SER A 188
GLY A 196
GLU A 220
 None
 0.62A 3raeA-3ecqA:
undetectable
3raeC-3ecqA:
undetectable		 3raeA-3ecqA:
16.20
3raeC-3ecqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.15A 3tkwB-3ecqA:
undetectable		 3tkwB-3ecqA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.18A 3tl9B-3ecqA:
undetectable		 3tl9B-3ecqA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 11 ALA A 615
LEU A 680
ILE A 667
LEU A 754
ILE A 693
 None
 1.12A 3tqbA-3ecqA:
undetectable		 3tqbA-3ecqA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 ARG A 140
THR A 138
VAL A 137
LEU A 150
 None
 0.98A 3uniA-3ecqA:
undetectable		 3uniA-3ecqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1012_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.21A 3w9tA-3ecqA:
0.0		 3w9tA-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.20A 3w9tB-3ecqA:
undetectable		 3w9tB-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.21A 3w9tC-3ecqA:
undetectable		 3w9tC-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.21A 3w9tD-3ecqA:
undetectable		 3w9tD-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.22A 3w9tE-3ecqA:
0.0		 3w9tE-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 ASP A 585
GLY A 589
TRP A 586
ASP A 468
 CA  A2000 ( 4.6A)
None
None
None
 1.20A 3w9tG-3ecqA:
0.0		 3w9tG-3ecqA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A1209
ASP A1061
ILE A1083
VAL A1084
LEU A1104
 None
 1.07A 4a81A-3ecqA:
undetectable		 4a81A-3ecqA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 GLU A1417
ILE A1418
GLU A1350
VAL A1381
 None
 1.06A 4ejwB-3ecqA:
undetectable		 4ejwB-3ecqA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 SER A1149
GLU A1198
GLY A1097
LYS A1080
 None
 1.05A 4fgzA-3ecqA:
undetectable
4fgzB-3ecqA:
undetectable		 4fgzA-3ecqA:
10.46
4fgzB-3ecqA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 ASP A 581
ASN A 579
ILE A 591
GLY A 589
ASP A 577
 CA  A2000 (-2.4A)
CA  A2000 (-2.8A)
None
None
CA  A2000 (-3.3A)
 1.46A 4fxsA-3ecqA:
2.5		 4fxsA-3ecqA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ARG A 670
GLY A 668
ASN A 663
GLN A 623
 None
 1.22A 4g0vB-3ecqA:
undetectable		 4g0vB-3ecqA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ASP A1207
ASP A1013
ASN A1090
ASP A1091
 None
 1.32A 4gkhJ-3ecqA:
undetectable		 4gkhJ-3ecqA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 SER A 911
TYR A 913
ALA A 851
GLY A 910
ASP A 181
 None
 1.43A 4iilA-3ecqA:
undetectable		 4iilA-3ecqA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		6 / 12 LEU A 360
GLY A 464
ALA A 465
VAL A 542
ILE A 484
VAL A 456
 None
 1.10A 4jecA-3ecqA:
undetectable		 4jecA-3ecqA:
5.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A1261
TRP A1284
LYS A 705
 None
 1.27A 4k7aA-3ecqA:
undetectable		 4k7aA-3ecqA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 611
ILE A 636
THR A 629
LEU A 630
THR A 610
 None
 1.04A 4km0B-3ecqA:
undetectable		 4km0B-3ecqA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 10 ALA A 578
ASP A 588
THR A 575
VAL A 573
MET A 597
 None
CA  A2000 (-2.3A)
None
None
None
 1.39A 4kq8A-3ecqA:
undetectable		 4kq8A-3ecqA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 LEU A 744
LYS A 751
GLU A 748
TYR A 664
 None
 1.00A 4lb2A-3ecqA:
undetectable		 4lb2A-3ecqA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A 253
VAL A 275
ASN A 177
 None
 0.71A 4lmnA-3ecqA:
undetectable		 4lmnA-3ecqA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 PHE A 184
ASP A 186
SER A 193
ALA A 237
 None
 1.18A 4lv9A-3ecqA:
2.5
4lv9B-3ecqA:
2.6		 4lv9A-3ecqA:
15.39
4lv9B-3ecqA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 HIS A 429
ALA A 406
VAL A 427
GLU A 552
 None
 1.25A 4n6pA-3ecqA:
0.0		 4n6pA-3ecqA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 GLN A 836
HIS A 835
ARG A 594
 None
 1.15A 4qyqA-3ecqA:
undetectable		 4qyqA-3ecqA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 GLN A 836
HIS A 835
ARG A 594
 None
 1.12A 4qyqB-3ecqA:
undetectable		 4qyqB-3ecqA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 TYR A 803
VAL A 511
ARG A 528
SER A 515
TRP A 549
 None
 1.31A 4rujA-3ecqA:
undetectable		 4rujA-3ecqA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ASN A 598
GLU A 802
LYS A 837
TYR A 593
 None
 1.15A 4wcxC-3ecqA:
2.1		 4wcxC-3ecqA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 ILE A 377
MET A 408
ALA A 406
ILE A 404
 None
 0.79A 4y03A-3ecqA:
undetectable		 4y03A-3ecqA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A1111
VAL A1191
VAL A1119
VAL A1121
LEU A1195
 None
 0.99A 4y0qA-3ecqA:
undetectable		 4y0qA-3ecqA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 TYR A1266
THR A1267
PHE A1402
GLY A 730
LEU A 712
 None
 1.15A 4ze0A-3ecqA:
undetectable		 4ze0A-3ecqA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 ASN A1048
SER A1066
TRP A1053
TYR A1060
 None
 1.36A 5amiB-3ecqA:
undetectable		 5amiB-3ecqA:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 TYR A 497
THR A 527
THR A 471
 None
 0.82A 5aoxB-3ecqA:
1.3		 5aoxB-3ecqA:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 TYR A 497
THR A 527
THR A 471
 None
 0.83A 5aoxE-3ecqA:
undetectable		 5aoxE-3ecqA:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 THR A1257
HIS A1352
LEU A1354
 None
 0.81A 5axdA-3ecqA:
undetectable		 5axdA-3ecqA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 THR A1257
HIS A1352
LEU A1354
 None
 0.82A 5axdC-3ecqA:
undetectable		 5axdC-3ecqA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASN A 774
SER A 771
ARG A 743
 None
 0.96A 5b2qA-3ecqA:
undetectable		 5b2qA-3ecqA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 VAL A 350
TYR A 353
VAL A 511
HIS A 545
 None
 0.98A 5eclA-3ecqA:
undetectable		 5eclA-3ecqA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 TYR A 652
GLY A 651
GLY A 656
HIS A 661
ASP A 658
 None
 1.39A 5f8yA-3ecqA:
undetectable		 5f8yA-3ecqA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 TYR A 652
GLY A 651
GLY A 656
HIS A 661
ASP A 658
 None
 1.40A 5f8yB-3ecqA:
undetectable		 5f8yB-3ecqA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 TRP A1380
PHE A1337
HIS A1352
THR A1257
 None
 1.46A 5hqaA-3ecqA:
9.9		 5hqaA-3ecqA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 TRP A1380
PHE A1337
HIS A1352
THR A1288
 None
 1.36A 5hqaA-3ecqA:
9.9		 5hqaA-3ecqA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 824
ALA A 839
GLY A 522
GLY A 798
GLY A 480
 None
 1.17A 5i71A-3ecqA:
undetectable		 5i71A-3ecqA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 824
ALA A 839
GLY A 522
GLY A 798
GLY A 480
 None
 1.22A 5i75A-3ecqA:
undetectable		 5i75A-3ecqA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 GLY A 619
ASP A 764
ILE A 693
TYR A 701
 None
 1.02A 5iwuA-3ecqA:
undetectable		 5iwuA-3ecqA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ILE A 786
ILE A 693
HIS A 694
VAL A 695
 None
 0.87A 5jmnA-3ecqA:
undetectable		 5jmnA-3ecqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 THR A1257
THR A1301
LEU A1413
 None
 0.58A 5m66D-3ecqA:
undetectable		 5m66D-3ecqA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 4 ASP A 658
HIS A 657
HIS A 694
HIS A 661
 None
 1.23A 5ncdD-3ecqA:
3.3		 5ncdD-3ecqA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 GLY A 644
ASP A 970
HIS A 892
ASP A 608
 None
 0.93A 5nnwD-3ecqA:
undetectable		 5nnwD-3ecqA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 GLY A 644
ASP A 970
HIS A 892
ASP A 608
 None
 0.97A 5no9D-3ecqA:
undetectable		 5no9D-3ecqA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 LEU A 246
GLY A 196
SER A 247
LEU A 265
ARG A 234
 None
 1.34A 5o96E-3ecqA:
undetectable
5o96F-3ecqA:
undetectable		 5o96E-3ecqA:
9.72
5o96F-3ecqA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 650
HIS A 657
HIS A 694
 None
 1.12A 5oexA-3ecqA:
2.5		 5oexA-3ecqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 650
HIS A 657
HIS A 694
 None
 1.12A 5oexB-3ecqA:
2.8		 5oexB-3ecqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 650
HIS A 657
HIS A 694
 None
 1.12A 5oexC-3ecqA:
2.6		 5oexC-3ecqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 650
HIS A 657
HIS A 694
 None
 1.10A 5oexD-3ecqA:
2.7		 5oexD-3ecqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 7 VAL A 572
ILE A 574
VAL A 502
PRO A 361
ALA A 509
 None
 1.21A 5ospA-3ecqA:
undetectable		 5ospA-3ecqA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 GLY A 842
TYR A 963
ASP A 884
ASP A 813
 None
None
None
GOL  A2003 (-3.6A)
 1.11A 5vlmE-3ecqA:
undetectable		 5vlmE-3ecqA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 241
VAL A 298
ARG A 234
ALA A 237
ALA A 236
 None
 0.99A 6c2mD-3ecqA:
undetectable		 6c2mD-3ecqA:
3.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 TYR A1158
GLU A1208
THR A1168
ASN A1177
 None
 1.13A 6c71B-3ecqA:
undetectable		 6c71B-3ecqA:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 9 LEU A1195
THR A1194
ILE A1074
PHE A1206
ILE A1095
 None
 1.31A 6ebpA-3ecqA:
undetectable		 6ebpA-3ecqA:
6.56