SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ed0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		5 / 12 ALA A  94
LEU A  21
SER A  85
ILE A  33
LEU A  36
 None
 1.04A 2oipE-3ed0A:
undetectable		 2oipE-3ed0A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		5 / 11 ILE A 104
MET A  74
ILE A  70
ALA A 147
ALA A 149
 None
 1.13A 2qhfA-3ed0A:
undetectable		 2qhfA-3ed0A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 5 LEU A 119
GLN A  76
THR A 138
HIS A 122
 None
 1.28A 2zj0B-3ed0A:
undetectable		 2zj0B-3ed0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 5 LEU A 119
GLN A  76
THR A 138
HIS A 122
 None
 1.35A 3ce6B-3ed0A:
undetectable		 3ce6B-3ed0A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 THR A  84
SER A  85
VAL A 135
GLY A  79
GLY A  78
 None
 1.21A 3ixlA-3ed0A:
undetectable		 3ixlA-3ed0A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		5 / 12 VAL A  30
GLY A  78
ILE A  20
ILE A  17
THR A  84
 None
 0.91A 4xdrA-3ed0A:
undetectable		 4xdrA-3ed0A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 8 PHE A  80
ALA A  44
LEU A 123
LEU A  81
 None
 1.20A 5dzkF-3ed0A:
undetectable
5dzkT-3ed0A:
undetectable		 5dzkF-3ed0A:
23.08
5dzkT-3ed0A:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 7 HIS A  16
ILE A  14
ARG A  24
GLN A  19
 None
 1.10A 5kkzC-3ed0A:
undetectable
5kkzE-3ed0A:
undetectable		 5kkzC-3ed0A:
18.28
5kkzE-3ed0A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 7 HIS A  16
ILE A  14
ARG A  24
GLN A  19
 None
 1.09A 5kkzK-3ed0A:
undetectable
5kkzQ-3ed0A:
undetectable		 5kkzK-3ed0A:
16.07
5kkzQ-3ed0A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		4 / 7 HIS A  16
ILE A  14
ARG A  24
GLN A  19
 None
 1.15A 5kkzM-3ed0A:
undetectable
5kkzO-3ed0A:
undetectable		 5kkzM-3ed0A:
18.28
5kkzO-3ed0A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3ed0 (3R)-HYDROXYMYRISTOY
L-ACYL CARRIER
PROTEIN DEHYDRATASE
(Helicobacter
pylori) 		5 / 12 ALA A  75
GLY A  78
SER A  77
VAL A  30
PHE A 101
 None
 1.14A 5w7pA-3ed0A:
undetectable		 5w7pA-3ed0A:
18.80