SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3edi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.17A 1os2A-3ediA:
9.9		 1os2A-3ediA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.18A 1os2D-3ediA:
10.0		 1os2D-3ediA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 12 LEU A  94
MET A  34
MET A  29
ILE A  19
ILE A  77
 None
DMS  A 215 ( 3.9A)
None
None
None
 1.29A 1osvB-3ediA:
undetectable		 1osvB-3ediA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.20A 1uttA-3ediA:
10.3		 1uttA-3ediA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.15A 1utzA-3ediA:
10.3		 1utzA-3ediA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.17A 1utzB-3ediA:
10.3		 1utzB-3ediA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 6 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.16A 1y93A-3ediA:
9.8		 1y93A-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		5 / 12 LEU A 193
MET A 147
SER A 145
LEU A 182
THR A   3
 None
None
ZN  A 211 ( 4.6A)
None
None
 1.39A 2aa5B-3ediA:
undetectable		 2aa5B-3ediA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.72A 2einN-3ediA:
undetectable		 2einN-3ediA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.17A 2hu6A-3ediA:
10.0		 2hu6A-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 8 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.27A 2jihB-3ediA:
6.4		 2jihB-3ediA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 6 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.11A 2ow9A-3ediA:
9.8		 2ow9A-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.13A 2ow9B-3ediA:
10.0		 2ow9B-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.12A 2ozrC-3ediA:
9.9		 2ozrC-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.22A 2ozrD-3ediA:
9.9		 2ozrD-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.33A 2ozrE-3ediA:
9.9		 2ozrE-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A  92
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.30A 2ozrF-3ediA:
9.8		 2ozrF-3ediA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.74A 3bvdA-3ediA:
undetectable		 3bvdA-3ediA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 6 ILE A  77
TYR A  17
MET A  29
HIS A  92
 None
DMS  A 215 (-4.3A)
None
ZN  A 210 (-3.2A)
 1.07A 3eteA-3ediA:
undetectable
3eteE-3ediA:
undetectable		 3eteA-3ediA:
18.84
3eteE-3ediA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 ILE A  77
TYR A  17
MET A  29
HIS A  92
 None
DMS  A 215 (-4.3A)
None
ZN  A 210 (-3.2A)
 1.08A 3eteB-3ediA:
undetectable
3eteC-3ediA:
undetectable		 3eteB-3ediA:
18.84
3eteC-3ediA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 7 MET A  29
HIS A  92
ILE A  77
TYR A  17
 None
ZN  A 210 (-3.2A)
None
DMS  A 215 (-4.3A)
 1.06A 3eteD-3ediA:
undetectable
3eteF-3ediA:
undetectable		 3eteD-3ediA:
18.84
3eteF-3ediA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.15A 3kecA-3ediA:
9.8		 3kecA-3ediA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A  92
GLU A  93
HIS A  96
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
 0.11A 3kecB-3ediA:
9.9		 3kecB-3ediA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.16A 3likA-3ediA:
10.1		 3likA-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.15A 3lilA-3ediA:
10.2		 3lilA-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.19A 3ljgA-3ediA:
10.3		 3ljgA-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.17A 3lkaA-3ediA:
9.9		 3lkaA-3ediA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.79A 3s33A-3ediA:
undetectable		 3s33A-3ediA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.75A 3s38A-3ediA:
undetectable		 3s38A-3ediA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.80A 3s3aA-3ediA:
undetectable		 3s3aA-3ediA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 6 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.18A 4a7bA-3ediA:
9.8		 4a7bA-3ediA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 4 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.17A 5n5jA-3ediA:
10.0		 5n5jA-3ediA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		4 / 5 HIS A  92
GLU A  93
HIS A  96
HIS A 102
 ZN  A 210 (-3.2A)
ZN  A 210 ( 4.3A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.14A 5n5kA-3ediA:
9.9		 5n5kA-3ediA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.68A 5x1fN-3ediA:
undetectable		 5x1fN-3ediA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3edi TOLLOID-LIKE PROTEIN
1
(Homo
sapiens) 		3 / 3 HIS A 102
HIS A  96
HIS A  92
 ZN  A 210 (-3.2A)
ZN  A 210 (-3.3A)
ZN  A 210 (-3.2A)
 0.77A 6hu9m-3ediA:
undetectable		 6hu9m-3ediA:
16.37