SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3edp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3edp LIN2111 PROTEIN
(Listeria
innocua) 		3 / 3 VAL A  51
ASP A  52
GLU A  33
 None
 0.53A 2qeuA-3edpA:
undetectable		 2qeuA-3edpA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3edp LIN2111 PROTEIN
(Listeria
innocua) 		3 / 3 VAL A  51
ASP A  52
GLU A  33
 None
 0.53A 2qeuC-3edpA:
2.4		 2qeuC-3edpA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3edp LIN2111 PROTEIN
(Listeria
innocua) 		4 / 6 PRO A  72
SER A 166
TYR A 147
THR A  26
 None
 0.98A 3tneA-3edpA:
undetectable		 3tneA-3edpA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3edp LIN2111 PROTEIN
(Listeria
innocua) 		4 / 5 TYR A  69
PHE A 101
LEU A 150
PRO A  72
 None
 1.45A 5csyB-3edpA:
undetectable		 5csyB-3edpA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3edp LIN2111 PROTEIN
(Listeria
innocua) 		3 / 3 LYS A   5
LYS A  14
SER A  13
 None
 0.92A 5odiA-3edpA:
undetectable		 5odiA-3edpA:
17.53