SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3edt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3edt KINESIN LIGHT CHAIN
2
(Homo
sapiens) 		4 / 7 TYR B 376
THR B 447
THR B 450
SER B 454
 None
 1.13A 1tv8B-3edtB:
undetectable		 1tv8B-3edtB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3edt KINESIN LIGHT CHAIN
2
(Homo
sapiens) 		5 / 12 LEU B 333
LEU B 330
ASN B 329
LEU B 327
LEU B 285
 None
 1.14A 1ya3C-3edtB:
undetectable		 1ya3C-3edtB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3edt KINESIN LIGHT CHAIN
2
(Homo
sapiens) 		3 / 3 HIS B 261
ASN B 264
ALA B 268
 None
 0.49A 5n4tB-3edtB:
undetectable		 5n4tB-3edtB:
24.40