SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ee9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		3 / 3 VAL A 194
VAL A 192
TRP A 203
 None
 0.90A 1av2A-3ee9A:
undetectable
1av2B-3ee9A:
undetectable		 1av2A-3ee9A:
9.57
1av2B-3ee9A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 11 ALA A 177
GLU A 159
ARG A 118
ALA A 132
LEU A 144
 None
 1.21A 1mjlA-3ee9A:
undetectable
1mjlB-3ee9A:
undetectable		 1mjlA-3ee9A:
19.84
1mjlB-3ee9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 158
ILE A 182
GLY A 183
GLY A 184
ILE A 128
 None
 0.77A 2avvA-3ee9A:
undetectable		 2avvA-3ee9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 158
ILE A 182
GLY A 183
GLY A 184
ILE A 128
 None
 0.80A 3cyxB-3ee9A:
undetectable		 3cyxB-3ee9A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		3 / 3 GLU A 172
ILE A 137
ALA A 202
 None
 0.60A 4wnwB-3ee9A:
undetectable		 4wnwB-3ee9A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3ee9 NON-STRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 ASP A 173
ASN A 176
ALA A 177
VAL A 180
 None
 0.63A 4zbqA-3ee9A:
undetectable		 4zbqA-3ee9A:
12.15